Experiment on ISIAH rats showed that antibodies to endothelial NO synthase in ultralow doses (impaza) produced a mild and progressive antihypertensive effect slightly inferior to that of losartan. The use of impaza is perspective in patients with erectile dysfunction and cardiovascular pathology.
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References
A. V. Martyushev-Poklad and O. I. Epshtein, Poliklinika No. 1, p. 8-9 (2003).
L. V. Shaplygin and S. V. Aliseiko, Men’s Health, No. 3, 68-70 (2006).
M. Burchardt, T. Burchardt, and A. G. Anastasiadis, et al., Int. J. Impot. Res., 13, No. 5, 276-281 (2001).
R.O.Cannon 3rd., Clin. Chem., 44, No. 8, Pt. 2, 1809-1819 (1998).
R. Maas, E. Schwedhelm, J. Albsmeier, and R. H. Boger, Vasc. Med., 7, No. 3, 213-225 (2002).
R. A. Stein, Rev. Urol. 5, Suppl. 7, S21-S27 (2003).
K. Wylie, Adv. Psychosom. Med., 29, 33-282 (2008).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, Suppl. 1, pp. 158-159, September, 2009
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Markel’, A.L., Zhavbert, E.S., Tarasov, S.A. et al. Effect of Impaza on Cardiovascular System. Bull Exp Biol Med 148, 518–519 (2009). https://doi.org/10.1007/s10517-010-0752-3
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DOI: https://doi.org/10.1007/s10517-010-0752-3