One-year monitoring of the blood metabolic parameters in residents of the North (students aged 18-20 years and scientists aged 30-59 years) showed that blood concentrations of glucose, lactate, and albumin varied in young people (18-20 years) within a greater range throughout the year than in older subjects (30-59 years), while the range of variations for triglycerides and cholesterol concentration was lesser in young subjects. Despite age-specific differences in metabolism, the seasonal dynamics of metabolite concentrations conforms to common regularities. The contribution of anaerobic glycolysis to the maintenance of energy homeostasis is greater during the fall-winter period, which leads to reduction of glycemic level to the lowest threshold normal level and to lactatacidosis. The concentrations of triglycerides increase significantly in winter, which indicates intensification of lipogenesis. Gluconeogenesis and aerobic oxidation of reserve lipids are intensified in the winter-spring period.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
A. P. Avtsyn, A. A. Zhavoronkov, A. G. Marachev, and A. P. Milovanov, Human Pathology in the North [in Russian], Moscow (1985).
N. A. Agadzhanyan and N. V. Ermakova, Ecological Portrait of Man in the North [in Russian], Moscow (1997).
E. R. Boiko, Fiziol. Chel., 22, No. 4, 122-129 (1996).
E. R. Boiko, Physiological and Biochemical Bases of Human Vital Activity in the North [in Russian], Ekaterinburg (2005).
L. A. Danilova, Blood and Urine Analyses [in Russian], St. Petersburg (1999).
N. R. Deryapa and I. F. Ryabinin, Adaptation of Humans in Polar Regions of the Earth [in Russian], Leningrad (1977).
V. P. Kaznacheev, V. Yu. Kulikov, and L. E. Panin, Mechanisms of Human Adaptation under Conditions of High Latitudes [in Russian], Leningrad (1980), pp. 10-24.
T. I. Kochan, Ekol. Chel., No. 10, 3-7 (2006).
A. N. Martinchik, A. K. Baturin, V. S. Baeva, et al., Album of Foodstuff Portions and Dishes [in Russian], Moscow (1995).
L. E. Panin, Energy Aspects of Adaptation [in Russian], Leningrad (1978).
V. N. Titov, Klin. Lab. Diagnost., No. 4, 3-10 (1999).
A. V. Tkachev, E. R. Boiko, Z. D. Gubkina, et al., The Endocrine System and Metabolism in Man in the North [in Russian], Syktyvkar (1992).
T. I. Kochan, Environment and Human Health, St. Petersburg (2003), pp. 780-781.
T. M. Makinen, T. Paakkonen, L. A. Palinkas, et al., Comp. Biochem. Physiol. A Mol. Integr. Physiol., 139, No. 2, 229-238 (2004).
A. M. Van Ooijen, W. D. Van Marken Lichtenbelt, A. A. Van Steenhoven, and K. R. Westerterp, Physiol. Behav., 82, No. 2, 543-553 (2004).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 147, No. 6, pp. 700-703, June, 2009
Rights and permissions
About this article
Cite this article
Kochan, T.I., Eseva, T.V. Seasonal Dynamics of Clinically Significant Metabolic Parameters in Northern Residents of Different Age. Bull Exp Biol Med 147, 757–759 (2009). https://doi.org/10.1007/s10517-009-0615-y
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-009-0615-y