Abstract
Oxidative and antioxidant parameters (content of LPO products and oxidized proteins, initial level of paraoxonase, content of α-tocopherol, retinol, and β-carotene) were studied at different stages of atherosclerotic foci development in coronary arteries: intact intima, lipid spot, stable young plaque, unstable plaque, stable plaque with fibrosis/calcinosis, and in various types of unstable plaques. The most typical sign of unstable plaques is high level of LPO products and low retinol content.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 11, pp. 500–502, November, 2007
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Ragino, Y.I., Chernyavski, A.M., Polonskaya, Y.V. et al. Oxidative and antioxidant changes during formation of unstable atherosclerotic plaque. Bull Exp Biol Med 144, 661–663 (2007). https://doi.org/10.1007/s10517-007-0398-y
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DOI: https://doi.org/10.1007/s10517-007-0398-y