Abstract
Antibiotic resistance markers were analyzed in C. trachomatis clinical isolates obtained after ineffective therapy of urogenital chlamydiasis with fluoroquinolones and macrolides. Heterotypical resistance to fluoroquinolones and macrolides was detected in all clinical isolates. No significant mutations in the target genes were detected.
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M. J. Blythe, B. P. Katz, B. E. Batteiger, et al., J. Pediatr., 121, No. 3, 487–493 (1992).
S. Dessus-Babus, C. M. Bebear, A. Charron, et al., Antimicrob. Agents Chemother., 42, No. 10, 2474–2481 (1998).
U. Dreses-Werringloer, I. Padubrin, B. Jurgens-Saathoff, et al., Ibid., 44, No. 12, 3288–3297 (2000).
U. Dreses-Werringloer, I. Padubrin, H. Zeidler, and I. Kohler, Ibid., 45, No. 11, 3001–3008 (2001).
R. J. Hogan, S. A. Mathews, S. Mukhopadnyay, et al., Infect. Immun., 74, No. 4, 1843–1855 (2004).
R. B. Jones, B. Van Der Pol, D. H. Martin, and M. K. Shepard, J. Infect. Dis., 162, No. 6, 1309–1315 (1990).
H. O. Kjaer, G. Dimcevski, G. Hoff, et al., Sex. Transm. Infect., 76, No. 3, 169–172 (2000).
C. Y. Lau and A. K. Qureshi, Sex. Transm. Dis., 29, No. 9, 497–502 (2002).
O. Y. Misyurina, E. V. Chipitsyna, Y. P. Finashutina, et al., Antimicrob. Agents Chemother., 48, No. 4, 1347–1349 (2004).
T. Notomi, Y. Ikeda, and A. Nagayama, Chemotherapy, 45, No. 4, 242–248 (1999).
R. A. Sayle and E. J. Milner-White, Trends Biochem. Sci., 20, No. 9, 374 (1995).
V. Skerk, I. Krhen, M. Lisik, et al., Int. J. Antimicrob. Agents, 24, No. 2, 188–191 (2004).
J. Somani, V. B. Bhullar, K. A. Workowski, et al., J. Infect. Dis., 181, No. 4, 1421–1427 (2000).
R. J. Suchland, W. M. Geisler, and W. E. Stamm, Antimicrob. Agents Chemother., 47, No. 2, 636–642 (2003).
J. D. Thompson, D. G. Higgins, and T. J. Gibson, Nucleic Acids Res., 22, 4673–4680 (1994).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 6, pp. 655–659, June, 2007
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Shkarupeta, M.M., Lazarev, V.N., Akopian, T.A. et al. Analysis of antibiotic resistance markers in Chlamydia trachomatis clinical isolates obtained after ineffective antibiotic therapy. Bull Exp Biol Med 143, 713–717 (2007). https://doi.org/10.1007/s10517-007-0221-9
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DOI: https://doi.org/10.1007/s10517-007-0221-9