Abstract
Pressure-threshold loads (ΔPT) are inspiratory force-related loads, which contrast with resistive loads (ΔR), are airflow-dependent loads. If detection of respiratory loads is a function of the background load, then pressure-threshold type inspiratory muscle strength training (IMST) would affect the detection of ΔPT but have less effect on detection of ΔR. ΔR and ΔPT detection and ventilatory responses were measured in healthy volunteers. IMST consisted of 4 sets of 6 breaths per day for 4 weeks, at 75% of maximal inspiratory pressure (MIP). MIP increased and a measure of inspiratory dirve, the mouth pressure generated in the initial 100 msec of an occluded inspiration (P0.1), decreased after IMST. IMST significantly increased MIP after 4 weeks of training. IMST did not change ΔR detection threshold and ΔR-breathing pattern. IMST decreased ΔPT detection percent and ΔPT-breathing pattern. Comparing ΔR and ΔPT at the same mouth pressure-generating level, the detection percent was different. We conclude that IMST affects the detection of ΔPT, but not ΔR. These results also suggest that mouth pressure is not the primary determinant of the inspiratory load detection. The significance of these results is that inspiratory pressure generating capacity can be increased by our pressure threshold training and this increase in respiratory muscle strength increases the ability of pulmonary patients to compensate for increased respiratory load and modulates the threshold for detection of changes in pulmonary mechanics.
Similar content being viewed by others
References
Altose, M. D., Dimarco, A. F., Gottfried, S. B., & Strohl, K. P. (1982). The sensation of respiratory muscle force. The American Review of Respiratory Disease, 126, 807–811.
Ambrosino, N., Opasich, C., Crotti, P., Cobelli, F., Tavazzi, L., & Rampulla, C. (1994). Breathing pattern, ventilatory drive and respiratory muscle strength in patients with chronic heart failure. European Respiratory Journal, 7, 17–22.
American Thoracic Society. (1995). Standardization of spirometry 1994 update. American Journal of Respiratory and Critical Care Medicine, 152(3), 1107–1136.
Burdon, J. G., Killian, K. J., Stubbing, D. G., & Campbell, E. J. (1983). Effect of background loads on the perception of added loads to breathing. Journal of Applied Physiology, 54, 1222–1228.
Campbell, E. J., Gandevia, S. C., Killian, K. J., Mahutte, C. K., & Rigg, J. R. (1980). Changes in the perception of inspiratory resistive loads during partial curarization. Journal of Physiology, 309, 93–100.
Davenport, P. W. (2008). Urge-to-cough: What can it teach us about cough? Lung, 186(Suppl 1), S107–S111.
Davenport, P. W. (2009). Clinical cough I: The urge-to-cough: A respiratory sensation. Handbook of Experimental Pharmacology, (187), 263–276.
Davenport, P. W., Dalziel, D. J., Webb, B., Bellah, J. R., & Vierck, C. J., Jr. (1991). Inspiratory resistive load detection in conscious dogs. Journal of Applied Physiology, 70, 1284–1289.
Davenport, P. W., & Revelette, W. R. (1996). Perception of respiratory mechanical events. In L. Adams & A. Guz (Eds.), Respiratory Sensation (pp. 101–124). New York: Marcel Dekker.
Goldman, M., Knudson, R. J., Mead, J., Peterson, N., Schwaber, J. R., & Wohl, M. E. (1970). A simplified measurement of respiratory resistance by forced oscillation. Journal of Applied Physiology, 28, 113–116.
Harver, A., Mahler, D. A., & Daubenspeck, J. A. (1989). Targeted inspiratory muscle training improves respiratory muscle function and reduces dyspnea in patients with chronic obstructive pulmonary disease. Annals of Internal Medicine, 111, 117–124.
Huang, C. H., Martin, A. D., & Davenport, P. W. (2003). Effect of inspiratory muscle strength training on inspiratory motor drive and RREP early peak components. Journal of Applied Physiology, 94, 462–468.
Kellerman, B. A., Martin, A. D., & Davenport, P. W. (2000). Inspiratory strengthening effect on resistive load detection and magnitude estimation. Medicine and Science in Sports and Exercise, 32, 1859–1867.
Killian, K. J., Bucens, D. D., & Campbell, E. J. (1982). Effect of breathing patterns on the perceived magnitude of added loads to breathing. Journal of Applied Physiology, 52, 578–584.
Lisboa, C., Villafranca, C., Leiva, A., Cruz, E., Pertuze, J., & Borzone, G. (1997). Inspiratory muscle training in chronic airflow limitation: Effect on exercise performance. European Respiratory Journal, 10, 537–542.
O’Donnell, D. E., Banzett, R. B., Carrieri-Kohlman, V., Casaburi, R., Davenport, P. W., Gandevia, S. C., et al. (2007). Pathophysiology of dyspnea in chronic obstructive pulmonary disease: a roundtable. Proceedings of the American Thoracic Society, 4, 145–168.
Redline, S., Gottfried, S. B., & Altose, M. D. (1991). Effects of changes in inspiratory muscle strength on the sensation of respiratory force. Journal of Applied Physiology, 70, 240–245.
Revelette, W. R., Zechman, F. W., Jr., Parker, D. E., & Wiley, R. L. (1984). Effect of background loading on perception of inspiratory loads. Journal of Applied Physiology, 56, 404–410.
Spinelli, A., Fanelli, A., Gorini, M., Sanna, A., Francois, C., & Scano, G. (1991). Control of breathing in patients with chronic pulmonary obstructive disease: Response to bamiphylline. Respiration, 58, 241–248.
Whitelaw, W. A., Derenne, J. P., & Milic-Emili, J. (1975). Occlusion pressure as a measure of respiratory center output in conscious man. Respiration Physiology, 23, 181–199.
Wiley, R. L., & Zechman, F. W., Jr. (1966). Perception of added airflow resistance in humans. Respiration Physiology, 2, 73–87.
Yan, S., & Bates, J. H. (1999). Breathing responses to small inspiratory threshold loads in humans. Journal of Applied Physiology, 86, 874–880.
Zechman, F. W., & Davenport, P. W. (1978). Temporal differences in the detection of resistive and elastic loads to breathing. Respiration Physiology, 34, 267–277.
Zechman, F. W., Muza, S. R., Davenport, P. W., Wiley, R. L., & Shelton, R. (1985). Relationship of transdiaphragmatic pressure and latencies for detecting added inspiratory loads. Journal of Applied Physiology, 58, 236–243.
Zhao, W., Martin, A. D., & Davenport, P. W. (2002). Detection of inspiratory resistive loads in double-lung transplant recipients. Journal of Applied Physiology, 93, 1779–1785.
Acknowledgments
This study was supported by a grant from the National Institutes of Health, NHLBI grant number HL47892.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Huang, C.H., Martin, A.D. & Davenport, P.W. Effects of Inspiratory Strength Training on the Detection of Inspiratory Loads. Appl Psychophysiol Biofeedback 34, 17–26 (2009). https://doi.org/10.1007/s10484-008-9073-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10484-008-9073-y