Abstract
We estimated joint associations between having history of alcohol use disorder (AUD) (based on prior ICD-9/ICD-10 codes) and recent self-reported alcohol use and viral non-suppression (≥ 1 viral load measurement > 20 copies/mL in the same calendar year as alcohol consumption was reported) among patients on ART enrolled in routine care, 2014–2018, in an urban specialty clinic. Among 1690 patients, 26% had an AUD, 21% reported high-risk alcohol use, and 39% had viral non-suppression. Relative to person-years in which people without AUD reported not drinking, prevalence of viral non-suppression was higher in person-years when people with AUD reported drinking at any level; prevalence of viral non-suppression was not significantly higher in person-years when people with AUD reported not drinking or person-years when people without AUD reported drinking at any level. No level of alcohol use may be “safe” for people with a prior AUD with regard to maintaining viral suppression.
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Funding
This work was supported by grants from the National Institutes of Health (K01 AA028193; K01 AI125087; K08 MH118094; K24 AA027483; U01 DA036935; U01 AI069918; U24 AA020801 and U01 AA020793).
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Lesko conceived of the research question, conducted the analysis, and wrote the first draft of the manuscript. Hutton, McCaul, Fojo, Moore, and Chander provided expert clinical insight and input on the study design. Edwards provided expert guidance on the analysis. Chander, Keruly, and Moore oversaw data collection. All authors have reviewed and approved of the manuscript as submitted.
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Lesko, C.R., Hutton, H.E., Edwards, J.K. et al. Alcohol Use Disorder and Recent Alcohol Use and HIV Viral Non-Suppression Among People Engaged in HIV Care in an Urban Clinic, 2014–2018. AIDS Behav 26, 1299–1307 (2022). https://doi.org/10.1007/s10461-021-03487-3
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DOI: https://doi.org/10.1007/s10461-021-03487-3