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Palliative Care in der Lungentransplantation

Palliative care in the setting of lung transplantation

  • Leitthema
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Der Pneumologe Aims and scope

Zusammenfassung

Hintergrund

Die erste Lungentransplantation (LTx) wurde bereits 1963 von James Hardy durchgeführt. Nach nun mehr als 50 Jahren sind weltweit über 32.000 Lungentransplantationen erfolgt. Damit ist die LTx für selektionierte Patienten mit fortgeschrittener Lungenkrankheit im Endstadium ein anerkanntes Verfahren. Die häufigsten zu einer LTx führenden Krankheitsentitäten sind Lungenfibrose, zystische Fibrose (CF), pulmonalarterielle Hypertonie (PAH) und COPD.

Fragestellung

Transplantations- und Palliativmedizin haben auf den ersten Blick gegensätzliche Ansätze, nämlich kurativ versus palliativ. Es stellt sich daher die Frage, ob sich Palliative Care in ein Lungentransplantationsprogramm integrieren und ein Nutzen vor und nach LTx für den Patienten, die Angehörigen und die Behandelnden erzielen lässt.

Implementierung von Palliative Care in die Transplantationsmedizin

Durch den kurativen Ansatz bei der LTx sind palliativmedizinische Konzepte bisher nur selten etabliert. Ein systematisches Vorgehen zur Integration der Palliative Care in das Lungentransplantationsprogramm existiert bis heute nicht, da noch immer klar definierte Kriterien fehlen. Im Vordergrund der Konsultation des Palliativteams zur Unterstützung der Behandlung von lungentransplantierten Patienten stehen u. a. folgende Anforderungen: End-of-life-Diskussion, Unterstützung der Familie, Schmerz- und Symptommanagement, psychologische Themen und Planung der Versorgung.

Schlussfolgerung

Palliative Care lässt sich sinnvoll in die Transplantationsmedizin integrieren. Sie kann in den Phasen vor und nach LTx einen wichtigen Platz in der Versorgung der Patienten einnehmen und Maßnahmen zur Unterstützung des Patienten und der Angehörigen beisteuern.

Abstract

Background

The first lung transplantation was performed in 1963 by James Hardy. After more than 50 years over 32,000 lung transplantations have been carried out worldwide and it is therefore an accepted procedure for selected patients in end stage advanced lung disease. The most common disease entities leading to lung transplantation are pulmonary fibrosis, cystic fibrosis (CF), primary pulmonary hypertension (PPH) and chronic obstructive pulmonary disease (COPD).

Objective

At first glance transplantation medicine and palliative care have opposite approaches, namely curative versus palliative. For this reason the question arises whether palliative care can be integrated into lung transplantation programs and achieve benefits before and after lung transplantation for patients, their families and care givers.

Implementation of palliative care into transplantation medicine

Because of the curative approach in lung transplantation, palliative care concepts have rarely been established. A systematic approach for the integration of palliative care into lung transplantation programs does not currently exist and a prerequisite would be clearly defined criteria, which have not yet been established. The focus of consultation of palliative teams to support the treatment of lung transplantation patients are end of life discussions, family support, pain and symptom management, psychological issues and planning of care.

Conclusion

Palliative care can be usefully integrated into transplantation medicine. In the phases before and after lung transplantation palliative care can fulfil an important role in the care of patients and thereby contribute measures to support patients and their families.

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Literatur

  1. Hardy JD, Webb WR, Dalton ML, Walker GR (1963) Lung homotransplantation in man. JAMA 186:1065–1074

    Article  CAS  PubMed  Google Scholar 

  2. Kotloff RM, Thabut G (2011) Lung transplantation. Am J Respir Crit Care Med 184:159–171

    Article  PubMed  Google Scholar 

  3. Hartert M, Senbaklavaci O, Gohrbandt B et al (2014) Lung transplantation: a treatment option in end-stage lung disease. Dtsch Arztebl Int 111:107–U28

    PubMed  PubMed Central  Google Scholar 

  4. ten Klooster L, Nossent GD, Erp JMK-V et al (2015) Ten-Year Survival in Patients with Idiopathic Pulmonary Fibrosis After Lung Transplantation. Lung. doi: 10.1007/s00408-015-9794-7

    PubMed  Google Scholar 

  5. Christie JD1, Edwards LB, Kucheryavaya AY, Benden C, Dipchand AI, Dobbels F, Kirk R, Rahmel AO, Stehlik J, Hertz MI; International Society of Heart and Lung Transplantation (2012) The Registry of the International Society for Heart and Lung Transplantation: 29th adult lung and heart-lung transplant report – 2012. J Heart Lung Transplant 31(10):1073-86. doi:10.1016/j.healun.2012.08.004

  6. Song M-K, De Vito Dabbs A, Studer SM, Arnold RM (2009) Palliative care referrals after lung transplantation in major transplant centers in the United States. Crit Care Med 37:1288–1292

    Article  PubMed  Google Scholar 

  7. Colman RE, Curtis JR, Nelson JE et al (2013) Barriers to optimal palliative care of lung transplant candidates. Chest 143:736–743

    Article  PubMed  PubMed Central  Google Scholar 

  8. Bennett D, Fossi A, Bargagli E et al (2015) Mortality on the waiting list for lung transplantation in patients with idiopathic pulmonary fibrosis: a single-centre experience. Lung 193:677–681

    Article  PubMed  Google Scholar 

  9. Brumley RD, Enguidanos S, Cherin DA (2003) Effectiveness of a home-based palliative care program for end-of-life. J Palliat Med 6:715–724

    Article  PubMed  Google Scholar 

  10. Colman R, Singer LG, Barua R, Downar J (2015) Outcomes of lung transplant candidates referred for co-management by palliative care: a retrospective case series. Palliat Med 29:429–435

    Article  PubMed  Google Scholar 

  11. Colman R, Singer LG, Barua R, Downar J (2015) Characteristics, interventions, and outcomes of lung transplant recipients co-managed with palliative care. J Palliat Med 18:266–269

    Article  PubMed  Google Scholar 

  12. Dellon EP, Leigh MW, Yankaskas JR, Noah TL (2007) Effects of lung transplantation on inpatient end of life care in cystic fibrosis. J Cyst Fibros 6:396–402

    Article  PubMed  PubMed Central  Google Scholar 

  13. Marciniuk DD, Goodridge D, Hernandez P et al (2011) Managing dyspnea in patients with advanced chronic obstructive pulmonary disease: a canadian thoracic society clinical practice guideline. Can Respir J 18:69–78

    PubMed  PubMed Central  Google Scholar 

  14. Mahler DA, Selecky PA, Harrod CG (2010) Management of dyspnea in patients with advanced lung or heart disease: practical guidance from the american college of chest physicians consensus statement. Pol Arch Med Wewn 120:160–166

    PubMed  Google Scholar 

  15. Lanken PN, Terry PB, DeLisser HM et al (2008) An official american thoracic society clinical policy statement: palliative care for patients with respiratory diseases and critical illnesses. Am J Respir Crit Care Med 177:912–927

    Article  PubMed  Google Scholar 

  16. Rocker GM, Simpson AC, Joanne Young BHSc et al (2013) Opioid therapy for refractory dyspnea in patients with advanced chronic obstructive pulmonary disease: patients’ experiences and outcomes. CMAJ Open 1:E27–E36. doi:10.9778/cmajo.20120031

    Article  PubMed  PubMed Central  Google Scholar 

  17. Currow DC, McDonald C, Oaten S et al (2011) Once-daily opioids for chronic Dyspnea: a dose increment and pharmacovigilance study. J Pain Symptom Manag 42:388–399

    Article  CAS  Google Scholar 

  18. Fuehner T, Kuehn C, Hadem J et al (2012) Extracorporeal membrane oxygenation in awake patients as bridge to lung transplantation. Am J Respir Crit Care Med 185:763–768

    Article  PubMed  Google Scholar 

  19. Warnecke G, Kühn C, Olsson KM et al (2011) Extracorporeal membrane oxygenation in fully awake patients as bridge to lung transplantation. Thorac Cardiovasc Surg 59:V221

    Google Scholar 

  20. Dellon EP, Shores MD, Nelson KI, Wolfe J (2010) Caregiver perspectives on discussions about the use of intensive treatments in cystic fibrosis. J Pain Symptom Manag 40(6):821–828

    Article  Google Scholar 

  21. Whitson BA, Hayes DJ (2014) Indications and outcomes in adult lung transplantation. J Thorac Dis 6:1018–1023. doi:10.3978/j.issn.2072-1439.2014.07.04

    PubMed  PubMed Central  Google Scholar 

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Correspondence to C. Schwarz.

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C. Schwarz gibt an, dass kein Interessenkonflikt besteht.

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O. Karg, Gauting

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Schwarz, C. Palliative Care in der Lungentransplantation. Pneumologe 13, 113–117 (2016). https://doi.org/10.1007/s10405-015-0019-9

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