Abstract
A 73-year-old man was diagnosed with essential thrombocythemia and treated with acetylsalicylic acid and hydroxyurea for 15 years. He was referred to our hospital for treatment of esophageal cancer detected by endoscopy. The cancer stage was T1N1M0, cStage IIB according to the classification of the Union for International Cancer Control, 7th edition. After administering two courses of preoperative chemotherapy (5-fluorouracil + cisplatin), the patient underwent video-assisted thoracoscopic radical esophagectomy. Hydroxyurea administration was discontinued during anticancer therapy and restarted to control the platelet count. Heparin was continuously infused during the perioperative period, and hydroxyurea was restarted through a jejunostomy tube on the postoperative day 2. No thrombosis or hemorrhage developed, and the patient was discharged from the hospital on the postoperative day 33. This is the first case report of video-assisted thoracoscopic radical esophagectomy for esophageal cancer in a patient with essential thrombocythemia.
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This report was in accordance with the Helsinki Declaration of 1975, as revised in 2000 and 2008. We gave consideration to the privacy of the patient, and the manuscript does not include any identifying information. The patient gave informed consent for publication of this work.
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Ryoya Hashiba, Shigeru Lee, Satoru Kishida, Yushi Fujiwara, Ken Gyobu, Yasunori Matsuda, Eijiro Edagawa, Masahiko Kinoshita, Toshio Ihara, Toshihiko Shibata and Harushi Osugi declare that they have no conflict of interest.
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Hashiba, R., Lee, S., Kishida, S. et al. A case of video-assisted thoracoscopic radical esophagectomy for cancer in a patient with essential thrombocythemia. Esophagus 13, 369–373 (2016). https://doi.org/10.1007/s10388-016-0535-7
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DOI: https://doi.org/10.1007/s10388-016-0535-7