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An Asian Patient with Intraocular Lymphoma Treated by Intravitreal Methotrexate

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Abstract

Background

To demonstrate the efficacy of intravitreal methotrexate for treating intraocular lymphoma.

Case

A 55-year-old immunocompetent Asian man was diagnosed with intraocular lymphoma.

Observations

The patient was initially managed by intravenous administration of high-dose methotrexate. Because vitreous cells persisted after systemic chemotherapy, methotrexate was given intravitreally thereafter. There was only self-limited corneal epitheliopathy without major complications following intraocular injections. Ocular remission was sustained during a 21-month follow-up.

Conclusion

Intravitreal methotrexate is an effective, repeatable, and safe treatment for intraocular lymphoma. Jpn J Ophthalmol 2006;50:474–478 © Japanese Ophthalmological Society 2006

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Authors and Affiliations

  1. Department of Ophthalmology, Far Eastern Memorial Hospital, Taipei, Taiwan

    Jia-Kang Wang & Andy Y. Lo

  2. Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan

    Chung-May Yang, Chang-Ping Lin & Yin-Dong Shan

  3. Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan

    Hwei-Fang Tien

Authors
  1. Jia-Kang Wang
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  2. Chung-May Yang
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  3. Chang-Ping Lin
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  4. Yin-Dong Shan
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  5. Andy Y. Lo
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  6. Hwei-Fang Tien
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Corresponding author

Correspondence to Chang-Ping Lin.

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Wang, JK., Yang, CM., Lin, CP. et al. An Asian Patient with Intraocular Lymphoma Treated by Intravitreal Methotrexate. Jpn J Ophthalmol 50, 474–478 (2006). https://doi.org/10.1007/s10384-005-0327-4

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  • DOI: https://doi.org/10.1007/s10384-005-0327-4

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