Skip to main content

Advertisement

Log in

Teeth whitening with 6% hydrogen peroxide and its impact on quality of life: 2 years of follow-up

  • Original Article
  • Published:
Odontology Aims and scope Submit manuscript

Abstract

This study aimed to evaluate color longevity after 2 years of whitening gel (6% hydrogen peroxide (HP), blue LED/infrared laser activation system) in comparison to a control 35% concentration in a split-mouth study and investigate the long-term effect on quality of life (QOL).Thirty-one patients were treated. Whitening using 6% or 35% HP gel was performed on half of the upper jaw in each patient. The color was measured at baseline and 1 week, 1 month, 1 and 2 years after treatment using the Easyshade Vita spectrophotometer and the Vita Bleached and Vita Classical Shade Guides organized by value. During 2 years of follow-up, color was evaluated before and after dental prophylaxis. Oral Health of Impact Profile (OHIP 14) and Psychosocial Impact Dental Aesthetics Questionnaire (PIDAQ) surveys measured QOL. Nineteen patients were evaluated at the 2-year follow-up. Significant differences in ΔE were measured between the two groups at all time points (p < 0.05). No significant differences in ΔSGU were observed at any time point (p > 0.05). The positive effect of bleaching on QOL was maintained in patients treated with a low concentration of the whitening gel. The two compounds remained effective after 2 years. An objective color difference was found between the groups, but no difference was observed in subjective reports. The positive effect on QOL remained after 2 years of follow-up in this cohort of patients.

ClinicalTrials.gov identifier NCT02353611.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Joiner A. The bleaching of teeth: a review of the literature. J Dent. 2006;34:412–9.

    Article  Google Scholar 

  2. Herrera A, Martin J, Perez F, et al. Is personality relevant in the choice of bleaching? Clin Oral Investig. 2016;20:2105–11.

    Article  PubMed  Google Scholar 

  3. Bortolatto JF, Trevisan TC, Bernardi PS, et al. A novel approach for in-office tooth bleaching with 6% HO/TiO_N and LED/laser system-a controlled, triple-blinded, randomized clinical trial. Lasers Med Sci. 2016;31:437–44.

    Article  Google Scholar 

  4. Martin J, Vildosola P, Bersezio C, et al. Effectiveness of 6% hydrogen peroxide concentration for tooth bleaching-A double-blind, randomized clinical trial. J Dent. 2015;43:965–72.

    Article  Google Scholar 

  5. Bortolatto JF, Pretel H, Floros MC, et al. Low Concentration H2O2/TiO_N in office bleaching: a randomized clinical trial. J Dent Res. 2014;93:66 s–71 s.

    Article  Google Scholar 

  6. Martín J, Ovies N, Cisternas P, et al. Can an LED-laser hybrid light help to decrease hydrogen peroxide concentration while maintaining effectiveness in teeth bleaching? Laser Phys. 2015;25:025608.

    Article  Google Scholar 

  7. Soares DG, Basso FG, Hebling J, de Souza Costa CA. Concentrations of and application protocols for hydrogen peroxide bleaching gels: effects on pulp cell viability and whitening efficacy. J Dent. 2014;42:185–98.

    Article  Google Scholar 

  8. Martin J, Fernandez E, Bahamondes V, et al. Dentin hypersensitivity after teeth bleaching with in-office systems. Randomized clinical trial. Am J Dent. 2013;26:10–4.

    Google Scholar 

  9. Meireles SS, Santos IS, Bona AD, Demarco FF. A double-blind randomized clinical trial of two carbamide peroxide tooth bleaching agents: 2-year follow-up. J Dent. 2010;38:956–63.

    Article  Google Scholar 

  10. Tay LY, Kose C, Herrera DR, Reis A, Loguercio AD. Long-term efficacy of in-office and at-home bleaching: a 2-year double-blind randomized clinical trial. Am J Dent. 2012;25:199–204.

    Google Scholar 

  11. Fernandez E, Bersezio C, Bottner J, et al. Longevity, esthetic perception, and psychosocial impact of teeth bleaching by low (6%) hydrogen peroxide concentration for in-office treatment: a randomized clinical trial. Oper Dent. 2017;42:41–52.

    Article  PubMed  Google Scholar 

  12. de Paula EA, Nava JA, Rosso C, et al. In-office bleaching with a two- and seven-day intervals between clinical sessions: a randomized clinical trial on tooth sensitivity. J Dent. 2015;43:424–9.

    Article  Google Scholar 

  13. Loguercio AD, Servat F, Stanislawczuk R, et al. Effect of acidity of in-office bleaching gels on tooth sensitivity and whitening: a two-center double-blind randomized clinical trial. Clin Oral Investig. 2017;21:2811–8.

    Article  Google Scholar 

  14. Bortolatto JF, Trevisan TC, Bernardi PS, et al. A novel approach for in-office tooth bleaching with 6% H2O2/TiO_N and LED/laser system-a controlled, triple-blinded, randomized clinical trial. Lasers Med Sci. 2016;31:437–44.

    Article  Google Scholar 

  15. Vildosola P, Vera F, Ramirez J, et al. Comparison of effectiveness and sensitivity using two in-office bleaching protocols for a 6% hydrogen peroxide gel in a randomized clinical trial. Oper Dent. 2017;42:244–52.

    Article  PubMed  Google Scholar 

  16. de Geus JL, Bersezio C, Urrutia J, et al. Effectiveness of and tooth sensitivity with at-home bleaching in smokers: a multicenter clinical trial. J Am Dent Assoc. 2015;146:233–40.

    Article  PubMed  Google Scholar 

  17. Paravina RD, Ghinea R, Herrera LJ, et al. Color difference thresholds in dentistry. J Esthet Restor Dent. 2015;27(Suppl 1):1–9.

    Article  Google Scholar 

  18. ADA (2012) Tooth whitening products: ADA statement on safety and effectiveness. https://www.ada.org/en/about-the-ada/ada-positions-policies-and-statements/tooth-whitening-safety-and-effectiveness. Accessed 6 Jun 2018.

  19. Montiel-Company JM, Bellot-Arcis C, Almerich-Silla JM. Validation of the psychosocial impact of dental aesthetics questionnaire (Pidaq) in Spanish adolescents. Med Oral Patol Oral Cir Bucal. 2013;18:e168–73.

    Article  PubMed  Google Scholar 

  20. Núñez L, Dreyer E, Martin J, Moncada G. Validation of the OHIP-aesthetic Sp questionnaire for chilean adults. The J Dent Oral Cran Epid. 2013;1:1–12.

    Google Scholar 

  21. Lesaffre E. The design and analysis of split-mouth studies: What statisticians and clinicians should know. Stats Med. 2015;28:3470–82.

    Article  Google Scholar 

  22. Demarco FF, Meireles SS, Masotti AS. Over-the-counter whitening agents: a concise review. Braz Oral Res. 2009;23(Suppl 1):64–70.

    Article  Google Scholar 

  23. Matis BA, Cochran MA, Eckert G. Review of the effectiveness of various tooth whitening systems. Oper Dent. 2009;34:230–5.

    Article  Google Scholar 

  24. Bortolatto JF, Pretel H, Floros MC, et al. Low concentration H2O2/TiO_N in office bleaching: a randomized clinical trial. J Dent Res. 2014;93:66–71.

    Article  Google Scholar 

  25. Bortolatto JF, Pretel H, Neto CS, et al. Effects of LED–laser hybrid light on bleaching effectiveness and tooth sensitivity: a randomized clinical study. Las Phys Let 2013;10:085601

    Article  Google Scholar 

  26. Chemin K, Rezende M, Loguercio AD, Reis A, Kossatz S. Effectiveness of and dental sensitivity to at-home bleaching with 4% and 10% hydrogen peroxide: a randomized, triple-blind clinical trial. Oper Dent. 2018;43:232–40.

    Article  PubMed  Google Scholar 

  27. Angel B, Estay, et al. Color stability, psychosocial impact, and effect on self-perception of esthetics of tooth whitening using low-concentration (6%) hydrogen peroxide. Quint Int. 2018. https://doi.org/10.3290/j.qi.a40468.

    Article  Google Scholar 

  28. Vildosola P, Bottner J, Avalos F, et al. Teeth bleaching with low concentrations of hydrogen peroxide (6%) and catalyzed by LED blue (450 +/- 10 nm) and laser infrared (808 +/- 10 nm) light for in-office treatment: Randomized clinical trial 1-year follow-up. J Esthet Restor Dent. 2017;29:339–45.

    Article  PubMed  Google Scholar 

  29. de Geus JL, Wambier LM, Kossatz S, Loguercio AD, Reis A. At-home vs in-office bleaching: a systematic review and meta-analysis. Oper Dent. 2016;41:341–56.

    Article  Google Scholar 

  30. de Geus JL, de Lara MB, Hanzen TA, et al. One-year follow-up of at-home bleaching in smokers before and after dental prophylaxis. J Dent. 2015;43:1346–51.

    Article  PubMed  Google Scholar 

  31. Swift EJ Jr, May KN Jr, Wilder AD Jr, Heymann HO, Bayne SC. Two-year clinical evaluation of tooth whitening using an at-home bleaching system. J Esthet Dent. 1999;11:36–42.

    Article  Google Scholar 

  32. Vano MDG, Barone A, Genovesi A, Covani U. Tooth bleaching with hydrogen peroxide and nano-hydroxyapatite: a 9-month follow-up randomized clinical trial. Int J Dent Hygiene. 2015;13:301–7.

    Article  Google Scholar 

  33. Matis BA, Wang G, Matis JI, Cook NB, Eckert GJ. White diet: is it necessary during tooth whitening? Oper Dent. 2015;40:235–40.

    Article  PubMed  Google Scholar 

  34. Karadas M, Seven N. The effect of different drinks on tooth color after home bleaching. Eur J Dent. 2014;8:249–53.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Rezende M, Loguercio AD, Reis A, Kossatz S. Clinical effects of exposure to coffee during at-home vital bleaching. Oper Dent. 2013;38:E229-36.

    Article  PubMed  Google Scholar 

  36. Meireles SS, Goettems ML, Dantas RV, et al. Changes in oral health related quality of life after dental bleaching in a double-blind randomized clinical trial. J Dent. 2014;42:114–21.

    Article  Google Scholar 

  37. Glick M, Williams DM, Kleinman DV, et al. Reprint of: A new definition for oral health supported by FDI opens the door to a universal definition of oral health. J Dent. 2017;57:1–3.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

The corresponding author dedicates this article to his two kids Elisa and Eduardo for their enormous inspiration.

Funding

Comisión Nacional de Investigación Científica y Tecnológica. Fondecyt 1170575.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Eduardo Fernández.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Bersezio, C., Martín, J., Angel, P. et al. Teeth whitening with 6% hydrogen peroxide and its impact on quality of life: 2 years of follow-up. Odontology 107, 118–125 (2019). https://doi.org/10.1007/s10266-018-0372-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10266-018-0372-3

Keywords

Navigation