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Recent analysis of status and outcomes of peritoneal dialysis in the Tokai area of Japan: the second report of the Tokai peritoneal dialysis registry

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Abstract

Background

Early withdrawal within 3 years after starting peritoneal dialysis (PD) and PD-related peritonitis have been major obstacles preventing increases in the population of PD patients. To address these problems, we implemented education programs for medical staff. This study analyzed the recent status and outcomes of PD therapy, focusing on findings such as the incidence and prognosis of peritonitis as of 5 years after our last study.

Methods

We investigated background, laboratory data and status of PD therapy, reasons for withdrawal from PD and incidental statements on peritonitis from 2010 to 2012 (R2), and compared findings with those from our last study of 2005–2007 (R1).

Results

Early PD therapy withdrawal in R2 clearly improved to 44.7 %, compared with 50.9 % in R1. Peritonitis incidence improved slightly from once per 42.8 months/patient in R1 to once per 47.3 months/patient in R2. Notably, PD-related peritonitis as a cause of mortality improved markedly in R2, but outcomes of PD-related peritonitis did not change significantly between R1 and R2. In contrast, social problems increased as a reason for withdrawal from PD therapy.

Conclusion

Our efforts at education might have been useful for improving early withdrawal from PD and deaths attributable to PD-related peritonitis. However, since improvements to incidence of PD-related peritonitis were limited by education, further improvement in PD-related peritonitis incidence requires development of new sterilized connecting systems during PD-bag exchanges to decrease PD-related peritonitis opportunities. Construction of medical support systems to address social problems is required to maintain long-term PD therapy.

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Acknowledgments

We offer our special thanks to Ms. Hane for her assistance in creating the database. We are also grateful to the medical and co-medical staff who helped with registration of PD patients and data collection for our registration system. This work was in part supported in part by the Ministry of Education, Culture, Sports, Science and Technology in Japan (Grants-in-Aids 24591227 and 15K09288 for Scientific Research).

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Authors and Affiliations

  1. Division of Nephrology, Renal Replacement Therapy, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, 466-8550, Japan

    Masashi Mizuno, Yasuhiko Ito, Yasuhiro Suzuki & Fumiko Sakata

  2. Division of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, Japan

    Masashi Mizuno, Yasuhiko Ito, Yasuhiro Suzuki, Fumiko Sakata, Shoichi Maruyama & Seiichi Matsuo

  3. Yokkaichi Municipal Hospital, Yokkaichi, Japan

    Yosuke Saka

  4. Kasugai Municipal Hospital, Kasugai, Japan

    Yosuke Saka & Tomohiko Naruse

  5. Konan Kosei Hospital, Konan, Japan

    Takeyuki Hiramatsu

  6. Anjo Kosei Hospital, Anjo, Japan

    Hirofumi Tamai

  7. Handa City Hospital, Handa, Japan

    Makoto Mizutani

  8. Ogaki Municipal Hospital, Ogaki, Japan

    Norimi Ohashi

  9. Nagoya Kyoritsu Hospital, Nagoya, Japan

    Hirotake Kasuga

  10. Chubu Rosai Hospital, Nagoya, Japan

    Hideaki Shimizu

  11. Toyota Kosei Hospital, Yoyota, Japan

    Hisashi Kurata

  12. Tosei General Hospital, Seto, Japan

    Kei Kurata

  13. Kainan Hospital, Yatomi, Japan

    Satoshi Suzuki

  14. Minami Seikyo Hospital, Nagoya, Japan

    Satoko Kido & Yoshikazu Tsuruta

  15. Ogaki Kita Clinic, Ogaki, Japan

    Teppei Matsuoka

  16. Daiyukai Daiichi Hospital, Ichinomiya, Japan

    Masanobu Horie

Authors
  1. Masashi Mizuno
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  2. Yasuhiko Ito
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  3. Yasuhiro Suzuki
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  4. Fumiko Sakata
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  5. Yosuke Saka
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  6. Takeyuki Hiramatsu
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  7. Hirofumi Tamai
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  8. Makoto Mizutani
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  9. Tomohiko Naruse
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  10. Norimi Ohashi
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  11. Hirotake Kasuga
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  12. Hideaki Shimizu
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  13. Hisashi Kurata
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  14. Kei Kurata
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  15. Satoshi Suzuki
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  16. Satoko Kido
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  17. Yoshikazu Tsuruta
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  18. Teppei Matsuoka
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  19. Masanobu Horie
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  20. Shoichi Maruyama
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  21. Seiichi Matsuo
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Corresponding author

Correspondence to Masashi Mizuno.

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Conflict of interest

Mizuno M, Suzuki Y and Ito Y worked in the Department of Renal Replacement Therapy as positions endowed by Baxter Japan at Nagoya University Graduate School of Medicine.

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Mizuno, M., Ito, Y., Suzuki, Y. et al. Recent analysis of status and outcomes of peritoneal dialysis in the Tokai area of Japan: the second report of the Tokai peritoneal dialysis registry. Clin Exp Nephrol 20, 960–971 (2016). https://doi.org/10.1007/s10157-016-1249-9

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  • DOI: https://doi.org/10.1007/s10157-016-1249-9

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