Skip to main content
Log in

Giant cell tumor of the sacrum treated with selective arterial embolization

  • Case Report
  • Published:
International Journal of Clinical Oncology Aims and scope Submit manuscript

Abstract

Giant cell tumor of the sacrum is extremely difficult to manage. Standard treatments, including surgery and radiation, are associated with significant complications and recurrence rates. In this manuscript, we report an early clinical result of a case of giant cell tumor of the sacrum successfully managed with selective arterial embolization. A 56-year-old woman underwent selective embolization for management of giant cell tumor of the sacrum. Radiologically, massive shrinkage of the extraosseous mass and increased peripheral ossification were obvious. Clinically, rapid pain relief was achieved and gait disability recovered. At final follow-up 28 months after completion of treatment, she retained normal activity in daily life. We stress the effectiveness of selective arterial embolization as a less invasive and less complicated primary treatment of giant cell tumors of the sacrum.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Golednberg RR, Campbell CJ, Bonfiglio M (1970) Giant-cell tumor of none: an analysis of two hundred and eighteen cases. J Bone Joint Surg 52-A:619–664

    Google Scholar 

  2. Turcotte RE, Sim FH, Unni KK (1993) Giant cell tumor of the sacrum. Clin Orthop 291:215–221

    PubMed  Google Scholar 

  3. Simpson AH, Porter A, Davis A et al (1995) Cephalad sacral resection with a combined extended ilioinguinal and posterior approach. J Bone Joint Surg 77-A:405–411

    Google Scholar 

  4. Ozaki T, Liljenqvist U, Halm H et al (2002) Giant cell tumor of the spine. Clin Orthop 401:194–201

    Article  PubMed  Google Scholar 

  5. Tomita K, Tsuchiya H (1990) Total sacrectomy and reconstruction for huge sacral tumors. Spine 15:1223–1227

    Article  CAS  PubMed  Google Scholar 

  6. Doita M, Harada T, Iguchi T et al (2003) Total sacrectomy and reconstruction for sacral tumors. Spine 28:E296–E301

    Article  PubMed  Google Scholar 

  7. Leggon RE, Zlotecki R, Reith J et al (2004) Scarborough MT giant cell tumor of the pelvis and sacrum. Clin Orthop 423:196–207

    Article  PubMed  Google Scholar 

  8. Lin PP, Guzel VB, Moura MF et al (2002) Long-term follow-up of patients with giant cell tumor of the sacrum treated with selective arterial embolization. Cancer 95:1317–1325

    Article  PubMed  Google Scholar 

  9. Lackman RD, Khoury LD, Esmail A et al (2002) The treatment of sacral giant-cell tumours by serial arterial embolization. J Bone Joint Surg 84-B:873–877

    Article  Google Scholar 

  10. Hosalkar HS, Jones KJ, King JJ et al (2007) Serial arterial embolization for large sacral giant-cell tumors. Spine 20:1107–1115

    Article  Google Scholar 

  11. Chang SS, Suratwala SJ, Jung KM et al (2004) Bisphosphonates may reduce in giant cell tumor by inducing apoptosis. Clin Orthop 426:193–199

    Google Scholar 

  12. Tse LF, Wong KC, Kumta SM et al (2008) Bisphosphonates reduce local recurrence in extremity giant cell tumor of bone: a case-control study. Bone 42:68–73

    Article  CAS  PubMed  Google Scholar 

  13. Gottfried ON, Schmidt MH, Stevens EA (2003) Embolization of sacral tumors. Neurosurg Focus 15:E4

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We thank M. K. Barrymore for comments on the manuscript. The authors did not receive and will not receive any benefits and funding from any commercial party related directly to the subject of this article.

Conflict of interest statement

No author has any conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mitsunori Kaya.

About this article

Cite this article

Onishi, H., Kaya, M., Wada, T. et al. Giant cell tumor of the sacrum treated with selective arterial embolization. Int J Clin Oncol 15, 416–419 (2010). https://doi.org/10.1007/s10147-010-0048-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10147-010-0048-7

Keywords

Navigation