Skip to main content
SpringerLink
Log in

Paragangliomas of the parasellar region

  • Original Article
  • Published:
Neurosurgical Review Aims and scope Submit manuscript

Abstract

Parasellar paragangliomas are rare tumors. As far as we know, only ten cases are described in the literature. Their clinical, pathological, and radiological features and possible origin are discussed in this article and a review of the literature is given. Additionally, we report a new case of a 51-year-old woman with paraganglioma growing in the anterior, middle, and posterior cranial fossa with extended destruction of the skull base. The patient had been suffering from long-standing headaches and facial nerve paresis. Preoperatively, this tumor was suspected to be a meningioma.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1.
Fig. 2.
Fig. 3.
Fig. 4.
Fig. 5.
Fig. 6.
Fig. 7.
Fig. 8.

Similar content being viewed by others

References

  1. Bilbao JM, Horvath E, Kovacs K, Singer W, Hudson AR (1978) Intrasellar paraganglioma associated with hypopituitarism. Arch Pathol Lab Med 102:95–98

    CAS  PubMed  Google Scholar 

  2. Burger PC, Scheithauer BW (1994) Tumors of the central nervous system. Atlas of tumor pathology. Armed Forces Institute of Pathology, Washington DC, pp 317–320

  3. Chytil S (1967) A case of nonchromaffin paraganglioma, originating in the suprasellar region and invading the nose through the sphenoid sinus. Cesk Otolaryngol 16:115–119

    CAS  PubMed  Google Scholar 

  4. Flint EW, Claassen D, Pang D, Hirsch WL (1993) Intrasellar and suprasellar paraganglioma: CT and MR findings. Am J Neuroradiol 14:1191–1193

    CAS  PubMed  Google Scholar 

  5. Ho KC, Meyer G, Garancis J, Hanna J (1982) Chemodectoma involving the cavernous sinus and semilunar ganglion. Human Pathol 13:942–943

    Article  CAS  Google Scholar 

  6. Kiewer KE, Cochran AJ (1989) A review of the histology, ultrastructure, immunohistology and molecular biology of extraadrenal paragangliomas. Arch Pathol Lab Med 113:1209–1218

    Google Scholar 

  7. Kiewer KE, Wen DR, Cancilla PA, Cochran AJ (1989) Paragangliomas: assessment of prognosis by histologic, immunohistochemical and ultrastructural techniques. Human Pathol 20:29–39

    Article  Google Scholar 

  8. Kleihues P, Cavenee WC (2000) Pathology and genetics of tumors of the nervous system. WHO and IARC, Lyon

  9. Kruse F (1960) Petrous ridge chemodectoma (nonchromograffin paraganglioma) simulating meningioma: case report. J Neurosurg 17:1108–1111

    Article  PubMed  Google Scholar 

  10. Lack ERE, Cubilla AL, Woodruff JM (1979) Paragangliomas of the head and neck region: a pathologic study of tumors from 71 patients. Human Pathol 10:191–218

    Article  CAS  Google Scholar 

  11. Mokry M, Kleinert R, Clarici G, Obermayer-Pietsch B (1998) Primary paraganglioma simulating pituitary macroadenoma: a case report and review of the literature. Neuroradiology 40:233–237

    Article  CAS  PubMed  Google Scholar 

  12. Noble ER, Smoker WR, Ghatak NR (1997) Atypical skull base paragangliomas. Am J Neuroradiol 18:986–990

    CAS  PubMed  Google Scholar 

  13. Orrison W (2000) Neuroimaging. Saunders, Salt Lake City

  14. Prabhakar S, Sawhney MS, Chopra JS, Kak VK, Banerjee AK (1984) Hemibase syndrome: an unusual presentation of intracranial paraganglioma. Surg Neurol 22:39–42

    Article  CAS  PubMed  Google Scholar 

  15. Salame K, Ouakine GE, Yossipov J, Rochkind S (2001) Paraganglioma of the pituitary fossa: diagnosis and management. J Neurooncol 54:49–52

    Article  CAS  PubMed  Google Scholar 

  16. Sambaziotis D, Kontogeorgos G, Kovacs K, Horvath E, Levedis A (1999) Intrasellar paraganglioma presenting as non-functioning pituitary adenoma. Arch Pathol Lab Med 123:429–432

    CAS  PubMed  Google Scholar 

  17. Sonneland PR, Scheithauer BW, Le Chago J, Crawford BG, Onofrio BM (1986) Paraganglioma of the cauda equina region. Clinicopathologic study of 31 cases with special reference to immunocytology and ultrastructure. Cancer 58:1720–1735

    Article  CAS  PubMed  Google Scholar 

  18. Scheithauer BW, Parameswaran A, Burdick B (1996) Intrasellar paraganglioma: report of a case in a sibship of von Hippel-Lindau disease. Neurosurgery 38:395–399

    Article  CAS  PubMed  Google Scholar 

  19. Steel T, Dailey AT, Born D, Berger MS, Mayberg MR (1993) Paragangliomas of the sellar region: report of two cases. Neurosurgery 32:844–847

    Article  CAS  PubMed  Google Scholar 

  20. Yamauchi T, Kubota M, Saeki N, Aihara N, Iwadate Y, Yamaura A (1999) Paraganglioma in the frontal skull base—case report. Neurol Med Chir (Tokyo) 39:308–312

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Krankenhaus der Barmherzigen Brüder, Nordallee 1, 54292, Trier, Germany

    F. Hertel & M. Bettag

  2. Department of Neuroradiology, Krankenhaus der Barmherzigen Brüder, Trier, Germany

    M. Mörsdorf

  3. Department of Neuropathology, University of the Saar, Homburg, Germany

    W. Feiden

Authors
  1. F. Hertel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Bettag
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Mörsdorf
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. W. Feiden
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to F. Hertel.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hertel, F., Bettag, M., Mörsdorf, M. et al. Paragangliomas of the parasellar region. Neurosurg Rev 26, 210–214 (2003). https://doi.org/10.1007/s10143-003-0266-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10143-003-0266-9

Keywords

Search

Navigation