Skip to main content
SpringerLink
Log in

Copolymerization and properties of multicomponent crosslinked hydrogels

  • Papers
  • Published:
Chinese Journal of Polymer Science Aims and scope Submit manuscript

Abstract

A series of multicomponent hydrogels were prepared by the copolymerization of hydrophobic silicon-containing monomer 3-bis(trimethylsilyloxy) methylsilylpropyl glycerol methacrylate (SiMA) with the solvent-responsive monomers 2-hydroxyethyl methacrylate (HEMA) and N-vinyl pyrrolidone (NVP) and thermosensitive monomer N,N-dimethyl acrylamide (DMA). 2-Hydroxy-2-methyl phenyl acetone (D-1173) was chosen as UV initiator and five different dienes/triene monomers were selected as crosslinking agent in order to select the best crosslinker. The ethanol extraction experiments as well as the FTIR, DSC and TG results showed that the copolymerization was effective. The optical, permeability, and mechanical analysis results demonstrated that the obtained hydrogels were highly transparent with good oxygen permeability and mechanical properties. And the impact of crosslinker on the mechanical properties of the hydrogels was also discussed in detail. The basic results demonstrated that the obtained hydrogels had good stimuli-responsive effects to both pH value and solvent.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Karadag, E., Saraydin, D., Caldiran, Y. and Guven, O., Polym. Adv. Technol., 2000, 11(2): 59

    Article  CAS  Google Scholar 

  2. Langer, R. and Peppas, N.A., Aiche J., 2003, 49(12): 2990

    Article  CAS  Google Scholar 

  3. Zhao, X. and Harris, J.M., J. Pharm. Sci., 1998, 87(11): 1450

    Article  CAS  Google Scholar 

  4. Li, Q.B., Han, Y.J., Yan, Q.Z. and Ge, C.C., Acta Polymerica Sinica (in Chinese), 2014, (4): 423

  5. Willis, S.L., Court, J.L., Redman, R.P., Wang, J.H., Leppard, S.W., O’Byrne, V.J., Small, S.A., Lewis, A.L., Jones, S.A. and Stratford, P.W., Biomaterials, 2001, 22(24): 3261

    Article  CAS  Google Scholar 

  6. Smirnov, M.A., Bobrova, N.V., Dmitriev, I.Y., Bukolsek, V. and Elyashevich, G.K., Polym. Sci. Ser. A, 2011, 53(1): 67

    Article  CAS  Google Scholar 

  7. Buyanov, A.L., Gofman, I.V., Khripunov, A.K., Tkachenko, A.A. and Ushakova, E.E., Polym. Sci. Ser. A, 2013, 55(5): 302

    Article  CAS  Google Scholar 

  8. Das, D., Das, R., Mandal, J., Ghosh, A. and Pal, S., J. Appl. Polym. Sci., 2014, 131(7): 12

    Article  Google Scholar 

  9. Kazanskii, K.S. and Dubrovskii, S.A., Adv. Polym. Sci., 1992, 10497

  10. Kim, B., Hong, D. and Chang, W.V., J. Appl. Polym. Sci., 2013, 130(5): 3574

    Article  CAS  Google Scholar 

  11. Zhang, J.Z., Xiao, C.S., Wang, J.C., Zhuang, X.L. and Chen, X.S., Chinese J. Polym. Sci., 2013, 31(12): 1697

    Article  CAS  Google Scholar 

  12. Cai, M.T., Zhang, J.X., Chen, Y.W., Cao, J., Leng, M.T., Hu, S.D. and Luo, X.L., Chinese J. Polym. Sci., 2014, 32(2): 236

    Article  CAS  Google Scholar 

  13. Xiao, Y., He, J.L., Tao, Y.F., Zhang, M.Z., Hu, J. and Ni, P.H., Acta Polymerica Sinica (in Chinese), 2014, (1): 122

  14. Mina, A.F. and Alam, M.A., Chinese J. Polym. Sci., 2005, 23(3): 269

    Article  CAS  Google Scholar 

  15. Jian, C.M., Liu, B.W., Chen, X., Zhou, S.T., Fang, T. and Yuan, J.Y., Chinese J. Polym. Sci., 2014, 32(6): 690

    Article  CAS  Google Scholar 

  16. Mahdavinia, G.R., Pourjavadi, A., Hosseinzadeh, H. and Zohuriaan, M.J., Eur. Polym. J., 2004, 40(7): 1399

    Article  CAS  Google Scholar 

  17. Pastoriza, A., Pacios, I.E. and Pierola, I.F., Polym. Int., 2005, 54(8): 1205

    Article  CAS  Google Scholar 

  18. Zhao, Y., Su, H.J., Fang, L. and Tan, T.W., Polymer, 2005, 46(14): 5368

    Article  CAS  Google Scholar 

  19. Rajagopal, K., Lamm, M.S., Haines-Butterick, L.A., Pochan, D.J. and Schneider, J.P., Biomacromolecules, 2009, 10(9): 2619

    Article  CAS  Google Scholar 

  20. Cavanagh, H.D., Ladage, P.M., Li, S.L., Yamamoto, K., Molai, M., Ren, D.H., Petroll, W.M. and Jester, J.V., Ophthalmology, 2002, 109(11): 1957

    Article  Google Scholar 

  21. Fonn, D., Situ, P. and Simpson, T., Optomet. Vis. Sci., 1999, 76(10): 700

    Article  CAS  Google Scholar 

  22. Mirejovsky, D., Patel, A.S. and Young, G., Biomaterials, 1993, 14(14): 1080

    Article  CAS  Google Scholar 

  23. Nicolson, P.C. and Vogt, J., Biomaterials, 2001, 22(24): 3273

    Article  CAS  Google Scholar 

  24. Ladage, P.M., Jester, J.V., Petroll, W.M., Bergmanson, J.P.G. and Cavanagh, H.D., Invest. Ophth. Vis. Sci., 2003, 44(3): 1056

    Article  Google Scholar 

  25. Nicolson, P.C., Eye & contact lens, 2003, 29(1 Suppl): S30

    Article  Google Scholar 

  26. Friends, G.D., Kunzler, J.F. and Ozark, R.M., Macromol. Symp., 1995, 98619

  27. Chekina, N.A., Pavlyuchenko, V.N., Danilichev, V.F., Ushakov, N.A., Novikov, S.A. and Ivanchev, S.S., Polym. Adv. Technol., 2006, 17(11–12): 872

    Article  CAS  Google Scholar 

  28. Chaouk, H., Wilkie, J.S., Meijs, G.F. and Cheng, H.Y., J. Appl. Polym. Sci., 2001, 80(10): 1756

    Article  CAS  Google Scholar 

  29. Lopour, P., Plichta, Z., Volfova, Z., Hron, P. and Vondracek, P., Biomaterials, 1993, 14(14): 1051

    Article  CAS  Google Scholar 

  30. Lopour, P., Vondracek, P., Janatova, V., Sulc, J. and Vacik, J., Biomaterials, 1990, 11(6): 397

    Article  CAS  Google Scholar 

  31. Tamaki, R., Chujo, Y., Kuraoka, K. and Yazawa, T., J. Mater. Chem., 1999, 9(8): 1741

    Article  CAS  Google Scholar 

  32. Lai, Y.C., J. Appl. Polym. Sci., 1995, 56(3): 301

    Article  CAS  Google Scholar 

  33. Lai, Y.C., J. Appl. Polym. Sci., 1995, 56(3): 317

    Article  CAS  Google Scholar 

  34. Lai, Y.C., J. Appl. Polym. Sci., 1996, 60(8): 1193

    Article  CAS  Google Scholar 

  35. Lai, Y.C., J. Polym. Sci., Part A: Polym. Chem., 1997, 35(6): 1039

    Article  CAS  Google Scholar 

  36. Pozuelo, J., Compan, V., Gonzalez-Meijome, J.M., Gonzalez, M. and Molla, S., J. Membr. Sci., 2014, 45262

  37. Kaczmarek, J.C., Tieppo, A., White, C.J. and Byrne, M.E., J. Biomater. Sci., Polym. Ed., 2014, 25(1): 88

    Article  CAS  Google Scholar 

  38. Wang, J.J. and Liu, F., J. Appl. Polym. Sci., 2013, 127(3): 2235

    Article  CAS  Google Scholar 

  39. Dai, Z., Yang, X.L. and Huang, W.Q., Chinese J. Polym. Sci., 2007, 25(3): 303

    Article  CAS  Google Scholar 

  40. Wu, R.L., Li, T. and Nies, E., Chinese J. Polym. Sci., 2013, 31(1): 21

    Article  CAS  Google Scholar 

  41. Argun, T., Senkal, B.F. and Erbil, C., J Polym Res, 2014, 21(3)

    Google Scholar 

  42. Wei, X., Champ, S. and Huglin, M.B., Polymer, 2001, 42(8): 3665

    Article  Google Scholar 

  43. Lou, X. and Van Coppenhagen, C., Polym Int, 2001, 50(3): 319

    Article  CAS  Google Scholar 

  44. Sakurai, K., Maegawa, T. and Takahashi, T., Polymer, 2000, 41(19): 7051

    Article  CAS  Google Scholar 

  45. Phan, T.N.T., Maiez-Tribut, S., Pascault, J.P., Bonnet, A., Gerard, P., Guerret, O. and Bertin, D., Macromolecules, 2007, 40(13): 4516

    Article  CAS  Google Scholar 

  46. Compan, V., Molla, S., Vallejos, S., Garcia, F., Garcia, J.M., Guzman, J. and Garrido, L., Macromol. Chem. Phys., 2014, 215(7): 624

    Article  CAS  Google Scholar 

  47. Higa, O.Z., Mendonca Faria, H.A. and de Queiroz, A.A.A., Radiat. Physic. Chem., 2014, 98118

    Google Scholar 

  48. Lou, X. and van Coppenhagen, C., Polym. Int., 2001, 50(3): 319

    Article  CAS  Google Scholar 

  49. Paterson, S.M., Shadforth, A.M.A. and Shaw, J.A., Mater. Sci. Eng. C, 2013, 33(8): 4917

    Article  CAS  Google Scholar 

  50. Lopez-Alemany, A., Compan, V. and Refojo, M.F., J. Biomed. Mater. Res., 2002, 63(3): 319

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. School of Chemistry and Chemical Engineering, Southeast University, Nanjing, 211189, China

    Zheng-bai Zhao, Shuang-shuang An, Hai-jiao Xie & Yong Jiang  (姜勇)

Authors
  1. Zheng-bai Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shuang-shuang An
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hai-jiao Xie
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yong Jiang  (姜勇)
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yong Jiang  (姜勇).

Additional information

This work was financially supported by the National Natural Science Foundation of China (No. 21174029) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhao, Zb., An, Ss., Xie, Hj. et al. Copolymerization and properties of multicomponent crosslinked hydrogels. Chin J Polym Sci 33, 173–183 (2015). https://doi.org/10.1007/s10118-015-1565-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10118-015-1565-7

Keywords

Search

Navigation