Abstract
We report a family with 6 members affected by a long-lasting paroxysmal exertion-induced dyskinesia. Fasting and stress were precipitating factors. All the patients of this family had also epileptic seizures mainly of generalised type with a favourable outcome. All patients were submitted to a neurophysiological study which included somatosensory evoked potentials by median nerve stimulation (MN-SEPs), somatosensory evoked potentials by posterior tibial nerve stimulation (PTN-SEPs), brainstem auditory evoked potentials (BAEPs), visual evoked potentials (VEPs), motor evoked potentials (MEPs) by magnetic transcranial cortical stimulation (TCS) and electromyography (EMG). The neurophysiological findings suggest a hyperexcitability at the muscular and brain membrane levels, probably due to an ion channel disorder.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 2 February 2000 / Accepted in revised form: 16 June 2000
Rights and permissions
About this article
Cite this article
Margari, L., Perniola, T., Illiceto, G. et al. Familial paroxysmal exercise-induced dyskinesia and benign epilepsy: a clinical and neurophysiological study of an uncommon disorder. Neurol Sci 21, 165–172 (2000). https://doi.org/10.1007/s100720070092
Issue Date:
DOI: https://doi.org/10.1007/s100720070092