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A dysphagia study in patients with sporadic inclusion body myositis (s-IBM)

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Abstract

The nature of the swallowing impairment in patients with sporadic inclusion body myositis (s-IBM) has not been well characterized. In this study, we examined ten consecutive s-IBM patients using videofluoroscopy (VF) and computed pharyngoesophageal manometry (CPM). The patients were divided into two groups: patients with complaint and without complaint of dysphagia. VF results indicated pharyngeal muscle propulsion (PP) at the hypopharyngeal and upper esophagus sphincter (UES) in all s-IBM patients. Patients without complaint of dysphagia showed a mild degree of PP, whereas a severe form of PP was observed in patients with complaint of dysphagia. CPM revealed that negative pressure during UES opening was not observed in the s-IBM patients with complaint of dysphagia. Incomplete opening and PP at the UES were observed in all s-IBM patients. These results indicate that the dysphagic processes occur subclinically in s-IBM patients who may not report swallowing impairments.

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References

  1. Lotz BP, Engel AG, Nishino H, Stevens JC, Litchy WJ (1989) Inclusion body myositis. Observations in 40 patients. Brain 112(Pt 3):727–747

    Article  PubMed  Google Scholar 

  2. Houser SM, Calabrese LH, Strome M (1998) Dysphagia in patients with inclusion body myositis. Laryngoscope 108:1001–1005

    Article  PubMed  CAS  Google Scholar 

  3. Wintzen AR, Bots GT, de Bakker HM, Hulshof JH, Padberg GW (1988) Dysphagia in inclusion body myositis. J Neurol Neurosurg Psychiatry 51:1542–1545

    Article  PubMed  CAS  Google Scholar 

  4. Danon MJ, Friedman M (1989) Inclusion body myositis associated with progressive dysphagia: treatment with cricopharyngeal myotomy. Can J Neurol Sci 16:436–438

    PubMed  CAS  Google Scholar 

  5. Dietz F, Logeman JA, Sahgal V, Schmid FR (1980) Cricopharyngeal muscle dysfunction in the differential diagnosis of dysphagia in polymyositis. Arthritis Rheum 23:491–495

    Article  PubMed  CAS  Google Scholar 

  6. Kagen LJ, Hochman RB, Strong EW (1985) Cricopharyngeal obstruction in inflammatory myopathy (polymyositis/dermatomyositis). Report of three cases and review of the literature. Arthritis Rheum 28:630–636

    Article  PubMed  CAS  Google Scholar 

  7. Griggs RC, Askanas V, DiMauro S, Engel A, Karpati G, Mendell JR, Rowland LP (1995) Inclusion body myositis and myopathies. Ann Neurol 38:705–713

    Article  PubMed  CAS  Google Scholar 

  8. Rosenbek JC, Robbins JA, Roecker EB, Coyle JL, Wood JL (1996) A penetration-aspiration scale. Dysphagia 11:93–98

    Article  PubMed  CAS  Google Scholar 

  9. Seaman WB (1966) Cineroentgenographic observations of the cricopharyngeus. Am J Roentgenol Radium Ther Nucl Med 96:922–931

    PubMed  CAS  Google Scholar 

  10. Kornblum C, Broicher R, Walther E, Seibel P, Reichmann H, Klockgether T, Herberhold C, Schroder R (2001) Cricopharyngeal achalasia is a common cause of dysphagia in patients with mtDNA deletions. Neurology 56:1409–1412

    Article  PubMed  CAS  Google Scholar 

  11. Shapiro J, Martin S, DeGirolami U, Goyal R (1996) Inflammatory myopathy causing pharyngeal dysphagia: a new entity. Ann Otol Rhinol Laryngol 105:331–335

    PubMed  CAS  Google Scholar 

  12. Cook IJ, Blumbergs P, Cash K, Jamieson GG, Shearman DJ (1992) Structural abnormalities of the cricopharyngeus muscle in patients with pharyngeal (Zenker’s) diverticulum. J Gastroenterol Hepatol 7:556–562

    Article  PubMed  CAS  Google Scholar 

  13. Verma A, Bradley WG, Adesina AM, Sofferman R, Pendlebury WW (1991) Inclusion body myositis with cricopharyngeus muscle involvement and severe dysphagia. Muscle Nerve 14:470–473

    Article  PubMed  CAS  Google Scholar 

  14. Suzuki N, Aoki M, Mori-Yoshimura M, Hayashi YK, Nonaka I, Nishino I (2011) Increase in number of sporadic inclusion body myositis (sIBM) in Japan. J Neurol. doi:10.1007/s00415-011-6185-8

  15. St Guily JL, Moine A, Perie S, Bokowy C, Angelard B, Chaussade S (1995) Role of pharyngeal propulsion as an indicator for upper esophageal sphincter myotomy. Laryngoscope 105:723–727

    Article  PubMed  CAS  Google Scholar 

  16. Cherin P, Pelletier S, Teixeira A, Laforet P, Simon A, Herson S, Eymard B (2002) Intravenous immunoglobulin for dysphagia of inclusion body myositis. Neurology 58:326

    Article  PubMed  CAS  Google Scholar 

  17. Liu LW, Tarnopolsky M, Armstrong D (2004) Injection of botulinum toxin A to the upper esophageal sphincter for oropharyngeal dysphagia in two patients with inclusion body myositis. Can J Gastroenterol 18:397–399

    PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Neurology, Wakayama Medical University, 840-1 Kimii-dera, Wakayama, 641-8510, Japan

    Ken-ya Murata & Tomoyoshi Kondo

  2. Department of Rehabilitation Medicine, Wakayama Medical University, 840-1 Kimii-dera, Wakayama, 641-8510, Japan

    Ken Kouda & Fumihiro Tajima

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  1. Ken-ya Murata
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  2. Ken Kouda
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  3. Fumihiro Tajima
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  4. Tomoyoshi Kondo
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Correspondence to Ken-ya Murata.

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Murata, Ky., Kouda, K., Tajima, F. et al. A dysphagia study in patients with sporadic inclusion body myositis (s-IBM). Neurol Sci 33, 765–770 (2012). https://doi.org/10.1007/s10072-011-0814-y

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  • DOI: https://doi.org/10.1007/s10072-011-0814-y

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