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Successful neridronate therapy in transient osteoporosis of the hip

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Abstract

We report on an uncommon case of bilateral transient osteoporosis of the hip (TOH) occurring in a young woman during pregnancy. The clinical features and the therapeutic action of intramuscular neridronate sodium, a third-generation amino-bisphosphonate, are underlined.

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References

  1. Schapira D (1992) Transient osteoporosis of the hip. Semin Arthritis Rheum 22:98–105

    Article  CAS  PubMed  Google Scholar 

  2. Lakhanpal S, Ginsburg WW, Luthara HS, Hunder GG (1987) Transient regional osteoporosis. A study of 56 cases and review of the literature. Ann Intern Med 106:444–450

    Article  CAS  PubMed  Google Scholar 

  3. Schapira D, Braun Moscovici Y, Gutierrez G, Nahir AM (2003) Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous bisphosphonates. Clin Exp Rheumatol 21:107–110

    CAS  PubMed  Google Scholar 

  4. Varenna M, Zucchi F, Binelli L, Failoni S, Gallazzi M, Sinigaglia L (2002) Intravenous pamidronate in the treatment of transient osteoporosis of the hip. Bone 31:96–101

    Article  CAS  PubMed  Google Scholar 

  5. Hunder GG, Kelly PJ (1968) Roentgenologic transient osteoporosis of the hip: a clinical syndrome? Ann Intern Med 76:973–976

    Google Scholar 

  6. Lequesne M (1968) Transient osteoporosis of the hip. A non-traumatic variety of Sudeck’s atrophy. Ann Rheum Dis 27:463–471

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Naides SJ, Resnick D, Zvaifler NJ (1984) Idiopathic regional osteoporosis: a clinical spectrum. J Rheumatol 12:763–768

    Google Scholar 

  8. Hayes CW, Conway WF, Daniel WW (1993) MR imaging of bone marrow edema pattern: transient osteoporosis, transient bone marrow edema syndrome, or osteonecrosis. Radiographics 23:1001–1011

    Article  Google Scholar 

  9. Guerra JJ, Steinberg ME (1995) Distinguishing transient osteoporosis from avascular necrosis of the hip. J Bone Joint Surg Am 77:616–624

    CAS  PubMed  Google Scholar 

  10. Froberg PK, Brunstein EM, Buckwalter A (1996) Osteonecrosis, transient osteoporosis and transient bone marrow edema. Radiol Clin North Am 34:273–291

    CAS  PubMed  Google Scholar 

  11. Assouline-Dayan Y, Chang C, Greenspan A, Shoenfeld Y, Gershwin ME (2002) Pathogenesis and natural history of osteonecrosis. Semin Arthritis Rheum 32:94–124

    Article  PubMed  Google Scholar 

  12. Sugano N, Atsumi T, Ohzono K, Kubo T, Hotokebuchi T, Takaota K (2002) The 2001 revised criteria for diagnosis, classification, and staging of idiopathic osteonecrosis of the femoral head. J Orthop Sci 7:601–605

    Article  PubMed  Google Scholar 

  13. Pinals RS, Jabbs JM (1972) Type IV hyperlipoproteinemia and transient osteoporosis. Lancet 2:929

    Article  CAS  PubMed  Google Scholar 

  14. Rozenbaum M, Zinman C, Nagler A, Pollack S (1984) Transient osteoporosis of hip joint with liver cirrhosis. J Rheumatol 11:241–243

    CAS  PubMed  Google Scholar 

  15. Rosen RA (1970) Transitory demineralization of the femoral head. Radiology 94:509–512

    CAS  PubMed  Google Scholar 

  16. Cayla J (1968) Algodystrophies reflexes des membres inferieurs d’origine vertebro-pelvienne. Prog Rheumatol 1:773

    Google Scholar 

  17. Doury P (1980) Regional osteoporosis of the hip treated with calcitonin-continued. J Rheumatol 7:14

    Google Scholar 

  18. Varenna M, Sinigaglia L, Binelli L, Beltrametti P, Gallazzi M (1996) Transient osteoporosis of the hip: a densitometric study. Clin Rheumatol 15:169–173

    Article  CAS  PubMed  Google Scholar 

  19. Bijl M, van Leeuwen MA, van Rijswijk MH (1999) Transient osteoporosis of the hip: presentation of (a)typical cases and a review of the literature. Clin Exp Rheumatol 17:601–604

    CAS  PubMed  Google Scholar 

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Correspondence to Giovanni La Montagna.

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La Montagna, G., Malesci, D., Tirri, R. et al. Successful neridronate therapy in transient osteoporosis of the hip. Clin Rheumatol 24, 67–69 (2005). https://doi.org/10.1007/s10067-004-0957-9

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