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Assessment of systemic inflammatory response after total extraperitoneal repair and Lichtenstein repair for inguinal hernia

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Abstract

Purpose

The aim of the study was assessment of the systemic inflammatory response (SIR) intensity by measuring the blood serum levels of high sensitivity C—reactive protein (hsCRP), Interleukin-6 (IL-6) and Total Leukocyte Counts of patients. The estimations were done before and after the patient underwent either open Lichtenstein or endoscopic TEP inguinal hernia repair. This is a prospective observational type of study.

Methods

Sixty patients with a diagnosis of unilateral uncomplicated inguinal hernia were included in the study. Patients were divided into two groups. In the first group, endoscopic total extraperitoneal repair (TEP) was done, while the other group underwent Lichtenstein repair. The patient selection was random. Serum markers for SIR were measured prior to and 24 h post-surgery.

Results

Total extraperitoneal repair (TEP) and open Lichtenstein inguinal hernia repair both cause a significant Systemic Inflammatory Response in the body. The rise in serum markers for SIR post-surgery was statistically significant in both the groups. The rise in serum hsCRP and IL-6 concentrations was observed to be equivocal among the two groups. Statistically significant difference was observed in serum TLC rise: Lichtenstein repair group having a higher value.

Conclusion

Both, open and endoscopic surgical techniques incite a systemic inflammatory response in the body. However, it cannot be conclusively stated that TEP is associated with lesser SIR compared to the Lichtenstein repair on the basis of this study.

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Author information

Authors and Affiliations

  1. Department of Surgery, Lady Hardinge Medical College and Associated Smt. Sucheta Kriplani Hospital, C-702, Panchsheel Apartments, Plot No. 24, Sector 4, Dwarka, New Delhi, Delhi, 110078, India

    M. Vats

  2. Department of Surgery, Lady Hardinge Medical College and Associated Smt. Sucheta Kriplani Hospital, C-604, Shaheed Bhagat Singh Road, Diz Area, Connaught Place, New Delhi, Delhi, 110001, India

    D. Pandey, S. Saha, N. Talwar, G. Saurabh, M. Andley & A. Kumar

Authors
  1. M. Vats
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  2. D. Pandey
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  3. S. Saha
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  4. N. Talwar
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  5. G. Saurabh
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  6. M. Andley
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  7. A. Kumar
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Corresponding author

Correspondence to M. Vats.

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Declaration

The authors declare that the study experiments comply with the current laws in India.

Funding

None.

Conflict of interest

MV, DP, SS, NT, GS, MA, and AK have declared no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and it’s later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all Individual participants included in the study.

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Vats, M., Pandey, D., Saha, S. et al. Assessment of systemic inflammatory response after total extraperitoneal repair and Lichtenstein repair for inguinal hernia. Hernia 21, 65–71 (2017). https://doi.org/10.1007/s10029-016-1543-1

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  • DOI: https://doi.org/10.1007/s10029-016-1543-1

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