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The future of stem cell therapy in hernia and abdominal wall repair

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Abstract

Introduction

Stem cell therapies have been proposed in preclinical trials as new treatment options in abdominal wall repair.

Materials and Methods

This work lists sources of feasible cell lines and the current status of literature and provides a cautious outlook into future developments. Special attention was paid to translational issues and practicabilty in a complex field.

Conclusion

Cell-based therapies will play a role in the clinical setting in the future. Regulatory and ethical issues need to be addressed as well as the proof of cost-effectiveness.

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Acknowledgments

The authors report that they have no disclosures or financial interests in conducting and publishing this review.

Author information

Authors and Affiliations

  1. Cluster for Tissue Regeneration, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstr 13, 1200, Vienna, Austria

    A. H. Petter-Puchner, S. Gruber-Blum & H. Redl

  2. Department of Visceral, General and Oncologic Surgery, Wilhelminenspital, Vienna, Austria

    A. H. Petter-Puchner, R. H. Fortelny & S. Gruber-Blum

  3. Paracelsus Medizinische Privatuniversität, Strubergasse 21, 5020, Salzburg, Austria

    R. H. Fortelny

  4. Department of General, Visceral, Vascular and Pediatric Surgery, University Hospital Wuerzburg, Wuerzburg, Germany

    U. Dietz

Authors
  1. A. H. Petter-Puchner
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  2. R. H. Fortelny
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  3. S. Gruber-Blum
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  4. H. Redl
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  5. U. Dietz
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Corresponding author

Correspondence to A. H. Petter-Puchner.

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Petter-Puchner, A.H., Fortelny, R.H., Gruber-Blum, S. et al. The future of stem cell therapy in hernia and abdominal wall repair. Hernia 19, 25–31 (2015). https://doi.org/10.1007/s10029-014-1288-7

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  • DOI: https://doi.org/10.1007/s10029-014-1288-7

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