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Different methods of mesh fixation in open retromuscular incisional hernia repair: a comparative study in pigs

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Abstract

Purpose

Reinforcement of the abdominal wall with alloplastic mesh material in incisional hernia repair is well established. To avoid dislocation and migration of the prostheses, mesh fixation is recommended. However, there seems to be a correlation between postoperative pain and mesh fixation. Furthermore, it remains unclear whether mesh fixation is necessary at all.

Methods

A retromuscular mesh implantation was performed in 36 pigs using a polypropylene-polyglecaprone 25 composite mesh (Ultrapro®, 12 × 18 cm). In group 1, the mesh was fixed to the posterior rectus sheet with non absorbable single sutures (Prolene® 2-0), in group 2 fixation was with absorbable sutures (Vicryl® 2-0), in group 3 mesh fixation was with 5 ml fibrin sealant (Quixil®), and, as a control, there was no fixation in group 4. The abdominal wall was explanted on postoperative day 7, 14 and 56. Mesh size and position was measured, and pull-out force of the mesh was analysed mechanically by tensiometry. The ratio of collagen type I/III was analysed to determine the quality of mesh integration.

Results

Neither mesh dislocation nor mesh migration was detected. Mesh size showed no significant differences, whether comparing time points or groups. No significant differences in the tensile strength of mesh integration were found when comparing the groups (group 1: 155 ± 17 mmHg; group 2: 175 ± 9 mmHg; group 3: 166 ± 24 mmHg; group 4: 172 ± 28 mmHg). Though the type I/III collagen ratio increased over time, no significant differences according to the type of fixation used were detected.

Conclusion

Mesh fixation in open incisional hernia repair with retromuscular mesh augmentation to avoid mesh dislocation or migration in the early postoperative period appears to be unnecessary.

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Acknowledgements

Financial support for this study was received from Johnson & Johnson Medical GmbH. The authors thank Mrs. Ellen Krott for her assistance and technical support.

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Authors and Affiliations

  1. Department of Vascular Surgery, University Hospital of RWTH Aachen, Pauwelsstr 30, 52074, Aachen, Germany

    J. Grommes

  2. Department of Surgery, University Hospital of RWTH Aachen, Aachen, Germany

    M. Binnebösel, C. D. Klink, K. T. von Trotha, K. Junge & J. Conze

Authors
  1. J. Grommes
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  2. M. Binnebösel
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  3. C. D. Klink
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  4. K. T. von Trotha
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  5. K. Junge
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  6. J. Conze
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Correspondence to J. Grommes.

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Grommes, J., Binnebösel, M., Klink, C.D. et al. Different methods of mesh fixation in open retromuscular incisional hernia repair: a comparative study in pigs. Hernia 14, 623–627 (2010). https://doi.org/10.1007/s10029-010-0725-5

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  • DOI: https://doi.org/10.1007/s10029-010-0725-5

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