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Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature

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Abstract

Purpose

We report the results of the intralesional steroid injections for the management of central giant cell granuloma (CGCG) of the jaws.

Methods

Seven CGCGs were treated with intralesional injection of corticosteroids. To accomplish this, 3.5 mL of triamcinolone and 3.5 mL of 0.5 % marcaine with 1/200,000 epinephrine (total 7 mL) were mixed. An adequate amount of steroid was injected into different areas of the lesion. This procedure was repeated on a weekly basis for 6 weeks.

Results

Clinical and radiological examination showed complete resolution and ossification of the lesions in four patients. Partial recovery was achieved in two patients. One patient did not respond to the treatment and underwent surgical curettage.

Conclusions

We suggest that intralesional steroid injection is safe and effective for the treatment of CGCG, especially in non-aggressive lesions.

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Authors and Affiliations

  1. Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Selçuk University, Konya, Turkey

    Doğan Dolanmaz

  2. Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Necmettin Erbakan University, Ankara Cd. No:75/A, Konya, Turkey

    Alparslan Esen

  3. Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Bezmialem University, Istanbul, Turkey

    Ahmet Mihmanlı

  4. Faculty of Dentistry, Department of Oral and Maxillofacial Surgery, Necmettin Erbakan University, Konya, Turkey

    Kubilay Işık

Authors
  1. Doğan Dolanmaz
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  2. Alparslan Esen
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  3. Ahmet Mihmanlı
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  4. Kubilay Işık
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Correspondence to Alparslan Esen.

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Dolanmaz, D., Esen, A., Mihmanlı, A. et al. Management of central giant cell granuloma of the jaws with intralesional steroid injection and review of the literature. Oral Maxillofac Surg 20, 203–209 (2016). https://doi.org/10.1007/s10006-015-0530-5

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  • DOI: https://doi.org/10.1007/s10006-015-0530-5

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