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Unspecific, idiopathic isolated osteolysis (Gorham–Stout syndrome) of the mandibular condylar process with its radiological, histological and clinical features: a case report and review of literature

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Abstract

Background

The unspecific, idiopathic isolated osteolysis is a rare condition in the various known osteopathies and better known as Gorham–Stout syndrome (Gorham's disease, GD). It belongs to the primary idiopathic osteolysis, and its aetiology is poorly understood. Many different localisations have been described, but there are only 48 cases affecting the maxillofacial region until now.

Case report

A 76-year-old patient with the singular localisation of GD in the left condylar process is presented. After radical resection of the condylar process, the clinical, radiological and pathological examinations made the diagnosis of GD. Until now, there is no recurrence for two and a half years.

Discussion

The unspecific and inconsistent clinical and radiological symptoms complicate the diagnosis of GD. Clinical, pathological and radiological correlation is essential to make the diagnosis. The different therapeutical options and the specific outcome are discussed.

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Oral and Maxillofacial Surgery and Facial Plastic Surgery, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle, Germany

    Konstanze Scheller & Christian Heinzelmann

  2. Institute of Pathology, Reilstrasse 129a, 06114, Halle, Germany

    Peter Herrmann-Trost, Linda Diesel & Christin Busse

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  1. Konstanze Scheller
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  2. Peter Herrmann-Trost
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  3. Linda Diesel
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  4. Christin Busse
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  5. Christian Heinzelmann
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Correspondence to Konstanze Scheller.

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Scheller, K., Herrmann-Trost, P., Diesel, L. et al. Unspecific, idiopathic isolated osteolysis (Gorham–Stout syndrome) of the mandibular condylar process with its radiological, histological and clinical features: a case report and review of literature. Oral Maxillofac Surg 18, 75–79 (2014). https://doi.org/10.1007/s10006-013-0394-5

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  • DOI: https://doi.org/10.1007/s10006-013-0394-5

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