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Effect of silanized nanosilica addition on remineralizing and mechanical properties of experimental composite materials with amorphous calcium phosphate

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Abstract

Objectives

Experimental composite resins with amorphous calcium phosphate (ACP) have the potential to regenerate demineralized tooth structures. The aim of the study was to investigate the effect of the addition of silanized silica nanofillers to the ACP-based composites on their mechanical properties and the kinetics of calcium and phosphate release.

Materials and methods

The test materials comprised 5 wt% (5-ACP) or 10 wt% (10-ACP) of silanized silica admixed to the 40 wt% ACP and 50 or 55 wt% resin. The ACP control (0-ACP) contained 40 wt% ACP and 60 wt% resin. Additionally, composite material CeramX (Dentsply, Germany) was included as control. Three-point bending test was performed to calculate flexural strength and modulus of elasticity. Inductively coupled plasma atomic emission spectroscopy was used for measurement of ion release. The micromorphology of calcium phosphate depositions on composite samples has been qualitatively evaluated using a scanning electron microscope. The results were analyzed using Mann–Whitney and Wilcoxon rank sum tests (α < 0.05).

Results

Ion release was enhanced by the silica fillers, when compared to the 0-ACP. Although not statistically significant, flexural strength of 10-ACP was improved by 46 % compared to 0-ACP. Flexural modulus of 5-ACP was significantly higher than 0-ACP.

Conclusions

The admixture of silanized fillers seems to be a promising approach for the improvement of mechanical and remineralizing properties of ACP composite resins.

Clinical relevance

ACP-based composite resins with modified composition could serve as an effective remineralizing aid as base materials in restorative dental medicine.

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Acknowledgments

This study was supported by Ministry of Science, Education and Sports, Republic of Croatia (065-0352851-0410 and 098-0982904-2952), Croatian Science Foundation, Forschungsgemeinschaft Dental, University Hospital Regensburg, University of Regensburg and NIDCR (DE13169). Generous contribution of the fillers from Evonik Degussa (Essen, Germany) and the monomers from Esstech (Essington, PA, USA) and Sigma Aldrich (Milwaukee, WI, USA) are gratefully acknowledged.

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Authors and Affiliations

  1. Department of Endodontics and Restorative Dentistry, School of Dental Medicine, University of Zagreb, Gunduliceva 5, 10000, Zagreb, Croatia

    Danijela Marovic & Zrinka Tarle

  2. Department of Operative Dentistry and Periodontology, University Hospital Regensburg, University of Regensburg, Franz-Josef-Strauss-Allee 11, D-93042, Regensburg, Germany

    Karl Anton Hiller & Gottfried Schmalz

  3. Institute of Physical and Theoretical Chemistry, University of Regensburg, Universitätsstraße 31, D-93053, Regensburg, Germany

    Rainer Müller

  4. Laboratory for Synthesis of New Materials, Division of Materials Chemistry, Ruđer Bošković Institute, Bijenička cesta 54, 10000, Zagreb, Croatia

    Mira Ristic

  5. Department of Prosthetic Dentistry, University Hospital Regensburg, University of Regensburg, Franz-Josef-Strauss-Allee 11, D-93042, Regensburg, Germany

    Martin Rosentritt

  6. Paffenbarger Research Center, ADA Foundation, 100 Bureau Dr. Stop 8546, Gaithersburg, MD, 20899, USA

    Drago Skrtic

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  1. Danijela Marovic
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Correspondence to Danijela Marovic.

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Marovic, D., Tarle, Z., Hiller, K.A. et al. Effect of silanized nanosilica addition on remineralizing and mechanical properties of experimental composite materials with amorphous calcium phosphate. Clin Oral Invest 18, 783–792 (2014). https://doi.org/10.1007/s00784-013-1044-x

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  • DOI: https://doi.org/10.1007/s00784-013-1044-x

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