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Vanadium carbide MXene: as a reductant for the synthesis of gold nanoparticles and its biosensing application

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Abstract

Vanadium carbide MXene (V2C) acts as a new type of two-dimensional (2D) graphene-like transition metal material that has attracted research interest. V2C has been widely used in various fields due to its excellent physical and chemical properties. Herein, the self-assembled V2C@gold nanoparticles (V2C@AuNPs) are prepared by water bath process at 80 °C. With the addition of glutathione (GSH), the absorbance (Abs.) at 550 nm of V2C@AuNPs was decreased. Therefore, an optical sensor is developed to detect GSH based on the properties of V2C@AuNPs. Under the optimal conditions, the detection range is 1–32 µM and the detection limit is 0.099 µM. Furthermore, the proposed GSH sensor exhibits high sensitivity, high selectivity, strong stability, and excellent recovery. The work will expand the application of V2C in biosensing.

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Acknowledgements

The work was financially supported by the National Natural Science Foundation of China (21964006), the Hunan Provincial Natural Science Foundation of China (2020JJ4640), the Scientific Research Fund of Hunan Provincial Education Department (20A050), the Changsha Science and Technology Planning Project (kq2203003) and the Scientific Research Found of Changsha University (SF1954), respectively.

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Correspondence to Haiyan Wang or Fuyou Du.

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Liu, C., Pan, H., Hu, H. et al. Vanadium carbide MXene: as a reductant for the synthesis of gold nanoparticles and its biosensing application. Amino Acids 54, 1173–1181 (2022). https://doi.org/10.1007/s00726-022-03173-1

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  • DOI: https://doi.org/10.1007/s00726-022-03173-1

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