Skip to main content
Log in

Metabotropic glutamate receptors

  • Editorial
  • Published:
Amino Acids Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • P Bonsi D Cuomo B Picconi G Sciamanna A Tscherter M Tolu G Bernardi P Calabresi A Pisani (2007) ArticleTitleStriatal metabotropic glutamate receptors as a target for pharmacotherapy in Parkinson’s disease Amino Acids 32 189–195

    Google Scholar 

  • SR Bradley DG Standaert KJ Rhodes HD Rees CM Testa AI Levey PJ Conn (1999) ArticleTitleImmunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia J Com Neurol 407 33–46 Occurrence Handle10.1002/(SICI)1096-9861(19990428)407:1<33::AID-CNE3>3.0.CO;2-G Occurrence Handle1:CAS:528:DyaK1MXisVGru7g%3D

    Article  CAS  Google Scholar 

  • J Cartmell DD Schoepp (2000) ArticleTitleRegulation of neurotransmitter release by metabotropic glutamate receptors J Neurochem 75 889–907 Occurrence Handle10936169 Occurrence Handle10.1046/j.1471-4159.2000.0750889.x Occurrence Handle1:CAS:528:DC%2BD3cXmtFykurY%3D

    Article  PubMed  CAS  Google Scholar 

  • PJ Conn JP Pin (1997) ArticleTitlePharmacology and functions of metabotropic glutamate receptors Annu Rev Pharmacol Toxicol 37 205–237 Occurrence Handle9131252 Occurrence Handle10.1146/annurev.pharmtox.37.1.205 Occurrence Handle1:CAS:528:DyaK2sXisl2ktr0%3D

    Article  PubMed  CAS  Google Scholar 

  • W Danysz CG Parsons I Bresnik G Quack (1996) ArticleTitleGlutamate in CNS Disorders Amino Acids 8 261–277

    Google Scholar 

  • CR Gerfen (2000) ArticleTitleMolecular effects of dopamine on striatal-projection pathways Trends Neurosci 23 IssueIDSuppl S64–S70 Occurrence Handle11052222 Occurrence Handle10.1016/S1471-1931(00)00019-7 Occurrence Handle1:CAS:528:DC%2BD3cXotVGrtLs%3D

    Article  PubMed  CAS  Google Scholar 

  • CR Gerfen TM Engber LC Mahan Z Susel TN Chase FJ Monsma SuffixJr DR Sibley (1990) ArticleTitleD1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons Science 250 1429–1432 Occurrence Handle2147780 Occurrence Handle10.1126/science.2147780 Occurrence Handle1:CAS:528:DyaK3MXjs1Gjsg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  • JC Gewirtz GJ Marek (2000) ArticleTitleBehavioral evidence for interactions between a hallucinogenic drug and group II metabotropic glutamate receptors Neuropsychopharmacology 23 569–576 Occurrence Handle11027922 Occurrence Handle10.1016/S0893-133X(00)00136-6 Occurrence Handle1:CAS:528:DC%2BD3cXntF2iu7Y%3D

    Article  PubMed  CAS  Google Scholar 

  • SR Glaum RJ Miller (1994) Acute Regulation of Synaptic Transmission by Metabotropic Glutamate Receptors PJ Conn J Patel (Eds) The metabotropic glutamate receptors Humana Press Totowa 147–172

    Google Scholar 

  • JA Kerner DG Standaert JB Penney SuffixJr AB Young GB Landwehrmeyer (1997) ArticleTitleExpression of group one metabotropic glutamate receptor subunit mRNAs in neurochemically identified neurons in the rat neostriatum neocortex, and hippocampus Mol Brain Res 48 259–269 Occurrence Handle9332723 Occurrence Handle10.1016/S0169-328X(97)00102-2 Occurrence Handle1:CAS:528:DyaK2sXksFamsL4%3D

    Article  PubMed  CAS  Google Scholar 

  • K Kłak A Palucha P Brański M Sowa A Pilc (2007) ArticleTitleCombined administration of a positive allosteric modulator of mGlu4 receptors PHCCC and of mGlu III receptor agonist ACPT-I evokes antidepressant-like effects in rats Amino Acids 32 169–172

    Google Scholar 

  • A Kłodzińska E Chojnacka-Wójcik A Pałucha P Brański P Popik A Pilc (1999) ArticleTitlePotential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models Neuropharmacology 38 1831–1839 Occurrence Handle10608278 Occurrence Handle10.1016/S0028-3908(99)00066-0

    Article  PubMed  Google Scholar 

  • A Kłodzińska K Tokarski M Bijak A Pilc (2002) ArticleTitleGroup II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice Pharmacol Biochem Behav 73 327–332 Occurrence Handle12117586 Occurrence Handle10.1016/S0091-3057(02)00845-6

    Article  PubMed  Google Scholar 

  • BD Kretschmer WJ Schmidt RM Kostrzewa M Herrera-Marschitz (2002) ArticleTitleAmino acids in neurobiology: neuroprotection and neurotoxic aspects of amino acids involved in neurotransmission and neuromodulation. General Introduction Amino Acids 23 1–7 Occurrence Handle12373510 Occurrence Handle10.1007/s007260200027 Occurrence Handle1:CAS:528:DC%2BD38Xns1Gnsro%3D

    Article  PubMed  CAS  Google Scholar 

  • JH Krystal LP Karper JP Seibyl GK Freeman R Delaney JD Bremner GR Heninger MB Bowers DS Charney (1994) ArticleTitleSubanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans – psychotomimetic, perceptual, cognitive, and neuroendocrine responses Arch Gen Psychiatry 51 199–214 Occurrence Handle8122957 Occurrence Handle1:CAS:528:DyaK2cXkslemtrY%3D

    PubMed  CAS  Google Scholar 

  • DS Lorrain CS Baccei LJ Bristow JJ Anderson MA Varney (2003) ArticleTitleEffects of ketamine and N-methyl-D-aspartate on glutamate and dopamine release in the rat prefrontal cortex: Modulation by a group II selective metabotropic glutamate receptor agonist LY379268 Neuroscience 117 697–706 Occurrence Handle12617973 Occurrence Handle10.1016/S0306-4522(02)00652-8 Occurrence Handle1:CAS:528:DC%2BD3sXhs1Khsrs%3D

    Article  PubMed  CAS  Google Scholar 

  • DM Lovinger BA McCool (1995) ArticleTitleMetabotropic glutamate receptor-mediated presynaptic depression at corticostriatal synapses involves mGLuR2 or 3 J Neurophysiol 73 1076–1083 Occurrence Handle7608756 Occurrence Handle1:CAS:528:DyaK2MXltFeqtLk%3D

    PubMed  CAS  Google Scholar 

  • ED Luby RC Cohen B Rosenbaum JS Gottlieb R Kelly (1959) ArticleTitleStudy of a new schizophrenomimetic drug: Sernyl Arch Neurol Psychiatry 81 363–369 Occurrence Handle1:STN:280:CyaD2Mrotlw%3D

    CAS  Google Scholar 

  • OJ Manzoni PE Castillo RA Nicoll (1995) ArticleTitlePharmacology of metabotropic glutamate receptors at the mossy fiber synapses of the guinea pig hippocampus Neuropharmacology 34 965–971 Occurrence Handle8532177 Occurrence Handle10.1016/0028-3908(95)00060-J Occurrence Handle1:CAS:528:DyaK2MXnvFKnsLc%3D

    Article  PubMed  CAS  Google Scholar 

  • GJ Marek RA Wright DD Schoepp JA Monn GK Aghajanian (2000) ArticleTitlePhysiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex J Pharmacol Exp Ther 292 76–87 Occurrence Handle10604933 Occurrence Handle1:CAS:528:DC%2BD3cXhslGntQ%3D%3D

    PubMed  CAS  Google Scholar 

  • PL Mc Geer JC Eccles EG Mc Geer (1987) Molecular neurobiology of the mammalian brain Plenum Press New York

    Google Scholar 

  • B Moghaddam (2004) ArticleTitleTargeting metabotropic glutamate receptors for treatment of the cognitive symptoms of schizophrenia Psychopharmacology 174 39–44 Occurrence Handle15205877 Occurrence Handle10.1007/s00213-004-1792-z Occurrence Handle1:CAS:528:DC%2BD2cXmvVahtLk%3D

    Article  PubMed  CAS  Google Scholar 

  • B Moghaddam BW Adams (1998) ArticleTitleReversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats Science 281 1349–1352 Occurrence Handle9721099 Occurrence Handle10.1126/science.281.5381.1349 Occurrence Handle1:CAS:528:DyaK1cXlvVentrw%3D

    Article  PubMed  CAS  Google Scholar 

  • DT Monaghan RJ Bridges CW Cotman (1989) ArticleTitleThe excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system Annu Rev Pharmacol Toxicol 29 365–402 Occurrence Handle2543272 Occurrence Handle10.1146/annurev.pa.29.040189.002053 Occurrence Handle1:CAS:528:DyaL1MXktVSku7Y%3D

    Article  PubMed  CAS  Google Scholar 

  • K Ossowska (1994) ArticleTitleThe role of excitatory amino acids in experimental models of Parkinson’s disease J Neural Transm 8 39–71 Occurrence Handle10.1007/BF02250917 Occurrence Handle1:CAS:528:DyaK2MXjs12gtbY%3D

    Article  CAS  Google Scholar 

  • K Ossowska (2005) Metabotropic glutamate receptors WJ Schmidt ME Reith (Eds) Dopamine and glutamate in psychiatric disorders Humana Press Totowa 117–149

    Google Scholar 

  • K Ossowska J Konieczny J Wardas M Pietraszek K Kuter S Wolfarth A Pilc (2007) ArticleTitleAn influence of ligands of metabotropic glutamate receptor subtypes on parkinsonian-like symptoms and the striatopallidal pathway in rats Amino Acids 32 179–188

    Google Scholar 

  • A Pałucha A Pilc (2005) ArticleTitleThe involvement of glutamate in the pathophysiology of depression Drug News Perspect 18 262–268 Occurrence Handle16034483 Occurrence Handle10.1358/dnp.2005.18.4.908661

    Article  PubMed  Google Scholar 

  • M Pietraszek J Nagel A Gravius D Schäfer W Danysz (2007) ArticleTitleThe role of group I metabotropic glutamate receptors in schizophrenia Amino Acids 32 173–178

    Google Scholar 

  • A Pilc A Kłodzińska P Brański G Nowak B Szewczyk E Tatarczyńska E Chojnacka-Wójcik J Wierońska (2002) ArticleTitleMultiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats Neuropharmacology 43 181–187 Occurrence Handle12213272 Occurrence Handle10.1016/S0028-3908(02)00082-5 Occurrence Handle1:CAS:528:DC%2BD38Xms1Gqtbk%3D

    Article  PubMed  CAS  Google Scholar 

  • JP Pin J Bockaert (1995) ArticleTitleGet receptive to metabotropic glutamate receptors Curr Opin Neurobiol 5 342–349 Occurrence Handle7580157 Occurrence Handle10.1016/0959-4388(95)80047-6 Occurrence Handle1:CAS:528:DyaK2MXmsl2hs70%3D

    Article  PubMed  CAS  Google Scholar 

  • A Pinna J Wardas N Simola M Morelli (2005) ArticleTitleNew therapies for treatment of Parkinson’s disease; adenosine A (2A) receptor antagonists Life Sci 77 3259–3267 Occurrence Handle15979104 Occurrence Handle10.1016/j.lfs.2005.04.029 Occurrence Handle1:CAS:528:DC%2BD2MXhtFShs7bF

    Article  PubMed  CAS  Google Scholar 

  • A Raz V Frechter-Mazar A Feingold M Abeles E Vaadia H Bergman (2001) ArticleTitleActivity of pallidal and striatal tonically active neurons is correlated in MPTP-treated monkeys but not in normal monkeys J Neurosci 21 RC128 Occurrence Handle11157099 Occurrence Handle1:STN:280:DC%2BD3M3msFemsQ%3D%3D

    PubMed  CAS  Google Scholar 

  • DD Schoepp (2001) ArticleTitleUnveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system J Pharmacol Exp Ther 299 12–20 Occurrence Handle11561058 Occurrence Handle1:CAS:528:DC%2BD3MXntFWltr4%3D

    PubMed  CAS  Google Scholar 

  • DD Schoepp BG Johnson JA Monn (1992) ArticleTitleInhibition of cyclic AMP formation by a selective metabotropic glutamate receptor agonist J Neurochem 58 1184–1186 Occurrence Handle1310724 Occurrence Handle10.1111/j.1471-4159.1992.tb09381.x Occurrence Handle1:CAS:528:DyaK38Xhs1Krs74%3D

    Article  PubMed  CAS  Google Scholar 

  • E Tatarczyńska A Pałucha B Szewczyk E Chojnacka-Wójcik J Wierońska A Pilc (2002) ArticleTitleAnxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats Pol J Pharmacol 54 707–710 Occurrence Handle12866729

    PubMed  Google Scholar 

  • A Ugolini F Bordi (1995) ArticleTitleMetabotropic glutamate group II receptors are responsible for the depression of synaptic transmission induced by ACPD in the dentate gyrus Eur J Pharmacol 294 403–410 Occurrence Handle8750700 Occurrence Handle10.1016/0014-2999(95)00560-9 Occurrence Handle1:CAS:528:DyaK28XntFWl

    Article  PubMed  CAS  Google Scholar 

  • JQ Wang JF McGinty (1996) ArticleTitleMuscarinic receptors regulate striatal neuropeptide gene expression in normal and amphetamine-treated rats Neuroscience 75 43–56 Occurrence Handle8923522 Occurrence Handle10.1016/0306-4522(96)00277-1 Occurrence Handle1:CAS:528:DyaK28XmslGhurs%3D

    Article  PubMed  CAS  Google Scholar 

  • JT Wroblewski W Danysz (1989) ArticleTitleModulation of glutamate receptors: molecular mechanisms and functional implications Annu Rev Pharmacol Toxicol 29 441–474 Occurrence Handle2543273 Occurrence Handle10.1146/annurev.pa.29.040189.002301 Occurrence Handle1:CAS:528:DyaL1MXktVSku7c%3D

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pilc, A., Ossowska, K. Metabotropic glutamate receptors. Amino Acids 32, 165–167 (2007). https://doi.org/10.1007/s00726-006-0315-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00726-006-0315-0

Navigation