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Cesium fluoride catalyzed Aza-Michael addition reaction in aqueous media

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Abstract

A green approach to the Aza-Michael addition reaction between an amine and α,β-unsaturated compounds has been achieved by conventional as well as non-conventional methods. The reaction is catalyzed by cesium fluoride (CsF) in aqueous media at ambient temperature to afford the product in excellent yield. Ultrasound irradiation has been used as a non-conventional energy source, which reduces the reaction time with improved product yield.

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Acknowledgments

The authors would like to thank Professor C. H. Gill, Head of the Department of Chemistry, and Dr. Babasaheb Ambedkar, Marathwada University, Aurangabad, for providing the necessary facilities.

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Authors and Affiliations

  1. Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, 431 004, Maharashtra, India

    Vilas B. Labade & Murlidhar S. Shingare

  2. Department of Chemistry, Vinayakrao Patil Mahavidyalaya, Vaijapur, 423 701, Aurangabad, India

    Shivaji S. Pawar

Authors
  1. Vilas B. Labade
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  2. Shivaji S. Pawar
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  3. Murlidhar S. Shingare
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Correspondence to Murlidhar S. Shingare.

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Labade, V.B., Pawar, S.S. & Shingare, M.S. Cesium fluoride catalyzed Aza-Michael addition reaction in aqueous media. Monatsh Chem 142, 1055–1059 (2011). https://doi.org/10.1007/s00706-011-0550-2

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