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Deprotection of Thioacetals Using K2S2O8/[bmim]Br as a Mild and Efficient Reagent under Solvent-Free Conditions

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Summary.

A straightforward and effective procedure for the deprotection of thioacetals to the corresponding carbonyl compounds using potassium persulfate and the ionic liquid [bmim]Br under solvent-free conditions is reported. A variety of aliphatic and aromatic 1,3-dithiolanes or 1,3-dithanes was deprotected to the corresponding carbonyl derivatives by this procedure.

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Authors and Affiliations

  1. Department of Pharmacology, University of Wisconsin Med. Sch., Madison, WI, USA

    Abdol R. Hajipour & Arnold E. Ruoho

  2. Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan, Iran

    Abdol R. Hajipour & Majid Mostafavi

Authors
  1. Abdol R. Hajipour
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  2. Majid Mostafavi
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  3. Arnold E. Ruoho
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Correspondence to Abdol R. Hajipour.

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Hajipour, A., Mostafavi, M. & Ruoho, A. Deprotection of Thioacetals Using K2S2O8/[bmim]Br as a Mild and Efficient Reagent under Solvent-Free Conditions. Monatsh. Chem. 138, 569–572 (2007). https://doi.org/10.1007/s00706-007-0650-1

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  • DOI: https://doi.org/10.1007/s00706-007-0650-1

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