Summary
A polymerase chain reaction test for the detection of ovine herpesvirus-2 (OHV-2) DNA was used to identify sites of OHV-2 infection in peri-natal lambs and in adult sheep. OHV-2 was detected in the nasal secretions from all lambs within a period of two months following birth. Subsequently, OHV-2 DNA was identified in a number of epithelial tissues including the cornea, turbinates and pharynx. In addition, OHV-2 DNA was detected exclusively in B-lymphocytes from six of ten adult sheep tested. An infection cycle for OHV-2 in sheep is proposed which bears similarities with the gammaherpesviruses Epstein-Barr virus and mouse herpesvirus-68.
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Received August 2, 1996 Accepted November 11, 1996
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Baxter, S., Wiyono, A., Pow, I. et al. Identification of ovine herpesvirus-2 infection in sheep. Arch. Virol. 142, 823–831 (1997). https://doi.org/10.1007/s007050050121
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DOI: https://doi.org/10.1007/s007050050121