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Coinfections of African swine fever virus, porcine circovirus 2 and 3, and porcine parvovirus 1 in swine in Nigeria

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Abstract

As pig production increases in Africa, it is essential to identify the pathogens that are circulating in the swine population to assess pig welfare and implement targeted control measures. For this reason, DNA samples collected from pigs in Nigeria in the context of African swine fever monitoring were further screened by PCR for porcine circovirus 2 (PCV-2), porcine circovirus 3 (PCV-3), and porcine parvovirus 1 (PPV1). Forty-seven (45%) pigs were positive for two or more pathogens. Sequence analysis identified PCV-2 genotypes a, b, and d, while limited genetic heterogenicity was observed among PCV-3 strains. All except one of the PPV1 sequences were genetically distinct from those previously identified in other countries.

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Fig. 1A
Fig. 1B
Fig. 1C

Data availability

Sequences generated in this study have been submitted to the GenBank database under accession numbers ON098525 to ON098596.

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Acknowledgments

We acknowledge the technical support of Dr. Maurice Naven, Dr. Toyin Olubade, and Abbas Waziri during this study. This study was supported by funds from the IAEA Peaceful Uses Initiative (PUI) VETLAB Network. The sequences were generated through the Sequencing Services of the Animal Production and Health sub-programme of the Joint Food and Agricultural Organization of the United Nations/International Atomic Energy Agency (IAEA) Division.

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Authors and Affiliations

  1. National Veterinary Institute, Vom, Plateau State, Nigeria

    Pam Dachung Luka, Adeyinka Jeremy Adedeji, Anvou R. Jambol, Isioma V. Ifende, Helen G. Luka, Nyam D. Choji & Rebecca Weka

  2. Animal Production and Health Laboratory, Animal Production and Health Section, Joint FAO/IAEA Division, Department of Nuclear Sciences and Applications, International Atomic Energy Agency, PO Box 100, 1400, Vienna, Austria

    Tirumala B.K. Settypalli, Giovanni Cattoli, Charles E. Lamien & William G. Dundon

  3. Battelle Memorial Institute, Charlottesville, Virgina, USA

    Jenna E. Achenbach

  4. School of Veterinary Medicine, Faculty of Health Sciences and Veterinary Medicine, University of Namibia, Neudamm Campus, Private Bag 13301, Windhoek, Namibia

    Umberto Molini

  5. Central Veterinary Laboratory (CVL), 24 Goethe Street, Private Bag 18137, Windhoek, Namibia

    Umberto Molini

  6. Dept. of Animal Medicine, Production and Health, University of Padova, Legnaro, viale dell’Università 16, 35020, Padova, Italy

    Giovanni Franzo

  7. Animal Production and Health Laboratory, IAEA, Friedenstrasse, 1, 2444, Seibersdorf, Austria

    William G. Dundon

Authors
  1. Pam Dachung Luka
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  14. William G. Dundon
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Corresponding author

Correspondence to William G. Dundon.

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William G. Dundon is an editor for Archives of Virology.

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No animal work was performed for this study

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Luka, P.D., Adedeji, A.J., Jambol, A.R. et al. Coinfections of African swine fever virus, porcine circovirus 2 and 3, and porcine parvovirus 1 in swine in Nigeria. Arch Virol 167, 2715–2722 (2022). https://doi.org/10.1007/s00705-022-05593-6

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