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Discovery of a virus of the species Enterovirus F in goats

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Abstract

Here, we report two novel enteroviruses, designated as SD-S67 and SD-S68, isolated from a goat farm. Their complete genome sequences were determined and found to be 7455 and 7465 nucleotides in length, respectively. Molecular characterization revealed that SD-S67 is closely related to bovine enterovirus strain 261 and that SD-S68 to caprine enterovirus strain CEV-JL14. Phylogenetic analysis showed that SD-S67 clustered with members of the species Enterovirus F, and that SD-S68 clustered with enteroviruses of goats and sheep. Recombination analysis showed that SD-S67 is likely to have undergone several recombination events in the process of its evolution. To the best of our knowledge, this is the first report of an enterovirus F isolate from a goat and of a coinfection with enteroviruses of different species in the same goat herd.

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Funding

This study was supported by the National Key Research & Development Program 2017YFD0500104 and 2016YFD0500904 and the National Natural Science Foundation of China (31572531).

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Author notes

  1. Xiaoran Chang, Qian Lin and Junying Hu contributed equally to this work.

Authors and Affiliations

  1. College of Veterinary Medicine, Key Laboratory for Zoonoses Research, Ministry of Education, Jilin University, 5333 Xian Road, Changchun, 130062, Jilin, China

    Xiaoran Chang, Qian Lin, Junying Hu, Xu Wang, Xin Li, Menglu Cai, Weiyu Wang, Zecai Zhang & Xinping Wang

  2. Key Laboratory for Zoonoses Research, Ministry of Education, Changchun, Jilin, China

    Xinping Wang

Authors
  1. Xiaoran Chang
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  2. Qian Lin
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  3. Junying Hu
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  4. Xu Wang
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  5. Xin Li
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  8. Zecai Zhang
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  9. Xinping Wang
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Contributions

Concept and design, Xinping Wang; virus isolation, Xiaoran Chang; PCR amplification, Xu Wang and Qian Lin; analysis and interpretation, Xiaoran Chang, Junying Hu, and Menglu Cai; sample collection, Junying Hu and Xin Li, confirmation, Zecai Zhang and Weiyu Wang; drafting and editing of the manuscript, Xiaoran Chang and Xinping Wang. All authors read and approved the final manuscript.

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Correspondence to Xinping Wang.

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The authors declare that there are no conflicts of interest.

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The article does not contain any studies with animals performed by any of the authors.

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Chang, X., Lin, Q., Hu, J. et al. Discovery of a virus of the species Enterovirus F in goats. Arch Virol 164, 2551–2558 (2019). https://doi.org/10.1007/s00705-019-04331-9

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