Abstract
This study aims to use probabilistic tractography to ascertain the global (GE) and local efficiency (LE) of the executive subnetwork in essential tremor (ET). Significantly lower GE of the whole executive subnetwork and lower LE of the left rostral middle frontal gyrus, frontal pole, inferior frontal gyrus, bilateral anterior cingulate cortex, and medial orbitofrontal cortex. These results imply ineffective and inadequate communication of the executive subnetwork, and may be causally associated with the executive dysfunction observed in ET.
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Symbiosis International University has received partial support from DST SERB (ECR/2016/000808) for setting up the computing facility.
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Supplementary Figure 1: Significant negative correlations observed between the local efficiency of the left pars orbitalis and WCST-perseverative responses, and between the local efficiency of the left anterior cingulate cortex and WCST-perseverative responses and errors. (TIFF 21,902 kb)
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Prasad, S., Shah, A., Saini, J. et al. Aberrant global and local efficiency of the executive subnetwork in essential tremor. J Neural Transm 127, 385–388 (2020). https://doi.org/10.1007/s00702-020-02141-x
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DOI: https://doi.org/10.1007/s00702-020-02141-x