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Twin-like appearance of an unruptured intracerebral anterior communicating artery (ACom) aneurysm in a male sibling of a patient with a ruptured ACom aneurysm

  • Case Report - Vascular
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Abstract

Background

Increased risk of intracranial aneurysm rupture with subsequent subarachnoid haemorrhage (SAH) is related to several possible factors, including first-grade familial aneurysms.

Methods and results

Here we present a case of one ruptured and one unruptured identical twin-like anterior communicating artery (ACom) aneurysm present in two male siblings, without any proven genetic predisposition. According to evidence-based scores, aneurysm rupture risk for the younger (51 years old) sibling (with an unruptured ACom aneurysm) would be low, leaving the decision for either treatment or clinical follow-up to the discretion of the treating physician.

Conclusions

From a clinical neurosurgical perspective, however, especially since his older brother suffered an aneurysmal SAH at age 57 (i.e. 6 life-years later) from a twin-like-appearing ACom aneurysm, in our opinion rupture seems almost inevitable, thus prompting treatment at an early stage.

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References

  1. Etiman N, Brown RD Jr, Beseoglu K, Juvela S, Raymond J, Morita A, Torner JC, Derdeyn CP, Raabe A, Mocco J, Koria M, Abdulazim A, Amin-Hanjani S, Al-Shahi Salman R, Barrow DL, Bederson J, Bonafe A, Dumont AS, Fiorella DJ, Gruber A, Hankey GJ, Hasan DM, Hoh BL, Jabbour P, Kasuya H, Kelly ME, Kirkpatrick PJ, Knuckey N, Koivisto T, Krings T, Lawton MT, Marotta TR, Mayer SA, Mee E, Pereira VM, Molyneux A, Morgan MK, Mori K, Murayama Y, Nagahiro S, Nakayama N, Niemelä M, Ogilvy CS, Pierot L, Rabinstein AA, Roos YB, Rinne J, Rosenwasser RH, Ronkainen A, Schaller K, Seifert V, Solomon RA, Spears J, Steiger HJ, Vergouwen MD, Wanke I, Wermer MJ, Wong GK, Wong JH, Zipfel GJ, Connolly ES Jr, Steinmetz H, Lanzino G, Pasqualin A, Rüfenacht D, Vajkoczy P, McDougall C, Hänggi D, LeRoux P, Rinkel GJ, MacDonald RL (2015) The unruptured intracranial aneurysm treatment score: a multidisciplinary consensus. Neurology 85(10):881–889

    Article  Google Scholar 

  2. Murayama Y, Takao H, Ishibashi T, Saguchi T, Ebara M, Yuki I, Arakawa H, Irie K, Urashima M, Molyneux AJ (2016) Risk analysis of unruptured intracranial aneurysms: prospective 10 year cohort study. Stroke 47:365–371

    PubMed  Google Scholar 

  3. Broderick JP, Brown RD, Sauerbeck MS, Hornung R, Huston J 3rd, Woo D, Anderson C, Rouleau G, Kleindorfer D, Flaherty ML, Meissner I, Foroud T, Moomaw EC, Connolly ES, FIA Study Investigators (2009) Greater rupture risk for familial as compared to sporadic unruptured intracranial aneurysms. Stroke 40:1952–1957

    Article  PubMed  PubMed Central  Google Scholar 

  4. Gaist D, Vaeth M, Tsiropoulos I, Christensen K, Corder E, Olsen J, Sorensen HT (2000) Risk of subarachnoid haemorrhage in first degree relatives of patients with subarachnoid haemorrhage: follow-up study based on national registries in Denmark. BMJ 320:141–145

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Bromberg JE, Rinkel GJ, Algra A, Limburg M, van Gijn J (1995) Outcome in familial subarachnoid hemorrhage. Stroke 26(6):961–963

    Article  CAS  PubMed  Google Scholar 

  6. Brown RD, Broderick JP (2014) Unruptured intracranial aneurysms: epidemiology, natural history, management options, and familial screening. Lancet Neurol 13:393–404

    Article  PubMed  Google Scholar 

  7. Teasdale GM, Drake CG, Hunt W, Kassell N, Sano K, Pertuiset B, De Villiers JC (1988) A universal subarachnoid hemorrhage scale: report of a committee of the World Federation of Neurosurgical Societies. J Neurol Neurosurg Psychiatry 51(11):1457

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Fisher C, Kistler J, Davis J (1980) Relation of cerebral vasospasm to subarachnoid hemorrhage visualized by computerized tomographic scanning. Neurosurgery 6(1):1–9

    Article  CAS  PubMed  Google Scholar 

  9. Steiner T, Juvela S, Unterberg A, Jung C, Forsting M, Rinkel G (2013) European Stroke Organization guidelines for the management of intracranial aneurysms and subarachnoid haemorrhage. Cerebrovasc Dis 35:93–112

    Article  PubMed  Google Scholar 

  10. Nieuwkamp DJ, Setz LE, Algra A, Linn FH, de Rooij NK, Rinkel GJ (2009) Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol 8:635–642

    Article  PubMed  Google Scholar 

  11. Greving JP, Wermer MJ, Brown RD, Morita A, Juvela S, Yonekure M, Ishibashi T, Torner JC, Nakayama T, Rinkel GJ, Algra A (2014) Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies. Lancet Neurol 13(1):59–66

    Article  PubMed  Google Scholar 

  12. Ruigrok YM, Rinkel GJ, Algra A, Raaymakers TW, van Gijn J (2004) Characteristics of intracranial aneurysms in patients with familial subarachnoid hemorrhage. Neurology 62(6):891–894

    Article  CAS  PubMed  Google Scholar 

  13. Ronkainen A, Niskanen M, Piironen R, Hernesniemi J (1999) Familial subarachnoid haemorrhage. Outcome study. Stroke 30(5):1099–1102

    Article  CAS  PubMed  Google Scholar 

  14. Teasdale GM, Wardlaw JM, White PM, Murray G, Teasdale EM, Easton V, Davie Cooper Scottish Aneurysm Study Group (2005) The familial risk of subarachnoid haemorrhage. Brain 128(Pt 7):1677–1685

    Article  PubMed  Google Scholar 

  15. Backes D, Rinkel GJ, Laban KG, Algra A, Vergouwen MD (2016) Patient- and aneurysm-specific risk factors for intracranial aneurysm growth: systematic review and meta-analysis. Stroke. doi:10.1161/STROKEAHA.115.012162

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Correspondence to Jorn Fierstra.

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Fierstra, J., Burkhardt, J.K., Stamou, S. et al. Twin-like appearance of an unruptured intracerebral anterior communicating artery (ACom) aneurysm in a male sibling of a patient with a ruptured ACom aneurysm. Acta Neurochir 158, 1051–1055 (2016). https://doi.org/10.1007/s00701-016-2782-8

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  • DOI: https://doi.org/10.1007/s00701-016-2782-8

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