Skip to main content
SpringerLink
Log in

Cure following gene therapy for recurrent glioblastoma multiforme?

  • Brief Report of a Special Case
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Summary

We report a patient with glioblastoma multiforme who is alive and disease-free 13 years following aggressive treatment with multiple surgeries, radiotherapy, chemotherapy, and gene therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • FW Floeth KJ Langen G Reifenberger F Weber (2003) ArticleTitleTumor-free survival of 7 years after gene therapy for recurrent glioblastoma Neurology 22 IssueID61 270–271

    Google Scholar 

  • NG Rainov (2000) ArticleTitleA phase III clinical evaluation of herpes simplex virus type thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme Human Gene Therapy 11 2389–2401 Occurrence Handle11096443 Occurrence Handle10.1089/104303400750038499 Occurrence Handle1:CAS:528:DC%2BD3cXosVGgt7g%3D

    Article  PubMed  CAS  Google Scholar 

  • JN Scott NB Rewcastle PMA Brasher D Fulton JA Mackinnon M Hamilton JG Caincross P Forsyth (1999) ArticleTitleWhich glioblastoma multiforme patient will become a long-term survivor? A population based study Ann Neurol 46 183–188 Occurrence Handle10443883 Occurrence Handle10.1002/1531-8249(199908)46:2<183::AID-ANA7>3.0.CO;2-7 Occurrence Handle1:STN:280:DyaK1MzntFCrsQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  • N Shand F Weber L Mariani M Bernstein A Gianella-Borradori Z Long AG Sorensen N Barbier (1999) ArticleTitleA phase 1–2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir Human Gene Therapy 20 IssueID10 2325–2335 Occurrence Handle10.1089/10430349950016979

    Article  Google Scholar 

  • CA Valery D Seilhean O Boyer B Marro JJ Hauw JL Kemeny C Marsault J Philippon D Klatzmann (2002) ArticleTitleLong-term survival after gene therapy for a recurrent glioblastoma Neurology 9 IssueID58 1109–1112

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Neurosurgery, Toronto Western Hospital, Toronto, Canada

    K. Karabatsou & M. Bernstein

Authors
  1. K. Karabatsou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Bernstein
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. Bernstein.

Additional information

Correspondence: Mark Bernstein, MD, FRCSC, Division of Neurosurgery, University of Toronto, Toronto Western Hospital, 399 Bathurst Street, 4 West Wing, M5T 2S8 Toronto, Ontario, Canada.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Karabatsou, K., Bernstein, M. Cure following gene therapy for recurrent glioblastoma multiforme?. Acta Neurochir (Wien) 150, 611–612 (2008). https://doi.org/10.1007/s00701-008-1579-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-008-1579-9

Search

Navigation