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Advances in enzyme-free electrochemical sensors for hydrogen peroxide, glucose, and uric acid

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Abstract

Enzyme-free (also called non-enzymatic or direct) electrochemical sensors have been widely used for the determination of hydrogen peroxide, glucose, and uric acid. This review covers the recent progress made in this field. We also discuss the respective sensor materials which have strong effect on the electro-catalytic properties of the electrodes and govern the performance of these sensors. In addition, perspectives and current challenges of enzyme-free electrochemical sensors are outlined. Contains 142 references.

In the recent past, publications related to enzyme-free electrochemical sensors became plentiful. In this paper, we give an overview on the recent developments of enzyme-free sensors including hydrogen peroxide, glucose and uric acid sensors.

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Acknowledgments

This research work was financially supported by the National Basic Research Program of China (2010CB732402) and the National Nature Scientific Foundation of China (21175112, 21375112 and 21305050), which are gratefully acknowledged. Professor John Hodgkiss of The University of Hong Kong is thanked for his assistance with English.

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Authors and Affiliations

  1. College of Biological Engineering, Jimei University, Xiamen, 361021, China

    Xiaomei Chen

  2. State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen, 361005, China

    Genghuang Wu & Xi Chen

  3. Ningde Amperex Technology Ltd., Ningde, 352100, China

    Genghuang Wu

  4. Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety, Fuzhou University, Fuzhou, 350002, China

    Zhixiong Cai

  5. Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto, 615-8520, Japan

    Xiaomei Chen & Munetaka Oyama

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  1. Xiaomei Chen
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  2. Genghuang Wu
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  3. Zhixiong Cai
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  4. Munetaka Oyama
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  5. Xi Chen
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Correspondence to Xi Chen.

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Chen, X., Wu, G., Cai, Z. et al. Advances in enzyme-free electrochemical sensors for hydrogen peroxide, glucose, and uric acid. Microchim Acta 181, 689–705 (2014). https://doi.org/10.1007/s00604-013-1098-0

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