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Electrochemical determination of hesperidin using mesoporous SiO2 modified electrode

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Abstract

Mesoporous SiO2 was synthesized and used for modification of the surface of a carbon paste electrode (CPE). In pH 8.0 phosphate buffer, an irreversible oxidation peak at 0.38 V is observed for hesperidin. Compared to the unmodified CPE, the modified CPE remarkably increases the oxidation signal of hesperidin. The effects of pH value, amount of mesoporous SiO2 and accumulation time were examined. As a result, a sensitive and convenient electroanalytical method was developed for hesperidin. Its linear range is from 0.5 to 25 μM, and the limit of detection is 0.25 μM. The method was applied to determine hesperidin in several traditional Chinese medicines.

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Acknowledgement

The authors are grateful for the financial support from the National Basic Research Program of China (973 Program, No. 2009CB320300).

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Authors and Affiliations

  1. MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, People’s Republic of China

    Dong Sun, Fengran Wang, Kangbing Wu, Jianwei Chen & Yikai Zhou

  2. School of Pharmacy, Wenzhou Medical College, Wenzhou, 325035, People’s Republic of China

    Dong Sun

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  1. Dong Sun
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  2. Fengran Wang
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  3. Kangbing Wu
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  4. Jianwei Chen
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  5. Yikai Zhou
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Correspondence to Yikai Zhou.

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Sun, D., Wang, F., Wu, K. et al. Electrochemical determination of hesperidin using mesoporous SiO2 modified electrode. Microchim Acta 167, 35 (2009). https://doi.org/10.1007/s00604-009-0200-0

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  • DOI: https://doi.org/10.1007/s00604-009-0200-0

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