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Malignant thymoma with direct invasion into the peritoneal cavity: Report of a case

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Abstract

Extrathoracic invasions or metastases from thymomas are extremely rare. We describe herein the case of a patient with malignant thymoma which recurred three times during an 8-year period and invaded directly into the peritoneal cavity, involving the gastrointestinal tract. The huge thymoma was completely resected, along with the fornix of the stomach, the transverse colon, and the 8th, 9th, and 10th ribs. Careful observation and multidisciplinary treatment against recurrent thymoma will be requisite for this patient, even though the tumor has been completely resected.

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References

  1. Brown RC, Cohen WN, Rose EF (1976) Malignant thymoma with penetration into the gastrointestinal tract: report of two cases. South Med J 69:409–412

    Article  PubMed  CAS  Google Scholar 

  2. Guillan RA, Zelman S, Smalley RL, Iglesias PA (1971) Malignant thymoma associated with myasthenia gravis, and evidence of extrathoracic metastases. An analysis of published cases and report of a case. Cancer 27:823–830

    Article  PubMed  CAS  Google Scholar 

  3. Wick MR, Nichols WC, Ingle JN, Bruckman JE, Okazaki H (1981) Malignant, predominantly lymphocytic thymoma with central and peripheral nervous system metastases. Cancer 47:2036–2043

    Article  PubMed  CAS  Google Scholar 

  4. Rosai J (1996) Mediastinum. Thymoma. In: Rosai J (ed) Ackerman’s surgical pathology. Mosby-Year Book, Missouri, pp 442–452

    Google Scholar 

  5. Lattes R (1962) Thymoma and other tumors of the thymus. An analysis of 107 cases. Cancer 15:1224–1260

    Article  Google Scholar 

  6. Bernatz PE, Khonsari S, Harrison EG, Taylor WF (1973) Thymoma: factors influencing prognosis. Surg Clin North Am 53:885–892

    PubMed  CAS  Google Scholar 

  7. Masaoka A, Monden Y, Nakahara K, Tanioka T (1981) Followup study of thymomas with special reference to their clinical stages. Cancer 48:2485–2492

    Article  PubMed  CAS  Google Scholar 

  8. Hoffman W, Moeller P, Manke HG, Otto HF (1985) Thymoma A clincopathologic study of 98 cases with special reference to three unusual cases. Pathol Res Pract 179:337–353

    Google Scholar 

  9. Martin JME, Randhawa G, Temple WJ (1986) Cervical thymoma. Arch Pathol Lab Med 10:354–357

    Google Scholar 

  10. Yamashita H, Murakami N, Noguchi S, Noguchi A, Yokoyama S, Moriuchi A, Nakayama I (1983) Acta Pathol Jpn 33:189–194

    PubMed  CAS  Google Scholar 

  11. Green WR, Pressoir R, Gumbs RV, Warner O, Naab T, Qayumi M (1987) Intrapulmonary thymoma. Arch Pathol Lab Med 111:1074–1076

    PubMed  CAS  Google Scholar 

  12. Baud M, Stamenkovic I, Kapanci Y (1981) Malignant thymomas. Clinicopathologic study of 13 cases. Prog Surg Pathol 3:129–146

    Google Scholar 

  13. Yamakawa Y, Masaoka A, Hashimoto T, Niwa H, Mizuno T, Fujii Y, Nakahara K (1991) A tentative tumor-node-metastasis classification of thymoma. Cancer 68:1984–1987

    Article  PubMed  CAS  Google Scholar 

  14. Tsuchiya R, Koga K, Matsuno Y, Mukai K, Shimosato Y (1994) Thymic carcinoma: proposal for pathological TNM and staging. Path Intern 44:505–512

    Article  CAS  Google Scholar 

  15. Lewis JE, Wick MR, Scheithauer BW, Bernatz PE, Taylor WF (1987) Thymoma. A clinicopathologic review. Cancer 60:2727–2743

    Article  PubMed  CAS  Google Scholar 

  16. Wang LS, Huang MH, Lin TS, Huang BS, Chien KY (1992) Malignant thymoma. Cancer 70:443–450

    Article  PubMed  CAS  Google Scholar 

  17. Wilkins EW, Edmunds LH, Castleman B (1966) Cases of thymoma at the Massachusetts General Hospital. J Thorac Cardiovasc Surg 52:322–330

    PubMed  Google Scholar 

  18. 18 Wekerle H, Ketelsen UP (1977) Intrathymic pathogenesis and dual genetic control of myasthenia gravis. Lancet 1:678–680

    Article  PubMed  CAS  Google Scholar 

  19. Meinl E, Klinkert WEF, Wekerle H (1991) The thymus in myasthenia gravis. Changes typical for the human disease are absent in experimental autoimmune myasthenia gravis of the Lewis rat. Am J Pathol 139:995–1008

    PubMed  CAS  Google Scholar 

  20. Carlson RW, Dorfman RF, Sikic BI (1990) Successful treatment of metastatic thymic carcinoma with cisplatin, vinblastine, bleomycin, and etoposide chemotherapy. Cancer 66:2092–2094

    Article  PubMed  CAS  Google Scholar 

  21. Chahinian AP, Bhardwaj S, Meyer RJ, Jaffrey IS, Kirschner PA, Holland JF (1981) Treatment of invasive or metastatic thymoma. Report of eleven cases. Cancer 47:1752–1761

    Article  PubMed  CAS  Google Scholar 

  22. Uematsu M, Kondo M (1986) A proposal for treatment of invasive thymoma. Cancer 58:1979–1985

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Abdomino-general Surgery, Tenri Hospital, 200 Mishima, 632, Tenri, Nara, Japan

    Takahisa Fujikawa, Yoshinori Nakamura, Satoru Matsusue & Hiroshi Takeda

  2. Department of Respiratory Medicine, Tenri Hospital, 200 Mishima, 632, Tenri, Nara, Japan

    Yoshiaki Kori

  3. Department of Thoracic Surgery, Tenri Hospital, 200 Mishima, 632, Tenri, Nara, Japan

    Makoto Sonobe

Authors
  1. Takahisa Fujikawa
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  2. Yoshinori Nakamura
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  3. Satoru Matsusue
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  4. Hiroshi Takeda
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  5. Yoshiaki Kori
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  6. Makoto Sonobe
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Fujikawa, T., Nakamura, Y., Matsusue, S. et al. Malignant thymoma with direct invasion into the peritoneal cavity: Report of a case. Surg Today 28, 451–454 (1998). https://doi.org/10.1007/s005950050163

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  • DOI: https://doi.org/10.1007/s005950050163

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