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Peritoneal and nodal recurrence 7 years after the excision of a ruptured solid pseudopapillary neoplasm of the pancreas: report of a case

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Abstract

A solid pseudopapillary neoplasm (SPN) of the pancreas is generally regarded as a neoplasm of low malignant potential and there is rarely recurrence of the disease. A 12-year-old female underwent a pylorus preserving pancreaticoduodenectomy for a ruptured pancreatic SPN following a blunt abdominal trauma. The tumor showed no pathological features suggesting malignant potential. Follow-up imaging studies depicted small nodules adjacent to the superior mesenteric vein 7 years after surgery. A laparotomy was performed, and exploration revealed 3 nodules adjacent to the superior mesenteric vein and 4 small nodules in the mesointestine. All of these lesions were extirpated, and were histologically confirmed to be nodal and peritoneal recurrence of SPN. This case indicates that SPN of the pancreas has a latent ability to recur, regardless of its benign pathological features, and peritoneal spread may be promoted by trauma. A close postoperative follow-up is thus mandatory in all patients with SPN even after a radical resection.

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References

  1. Frantz VK. Tumors of the pancreas. In: Anonymous Atlas of Tumor Pathology, Section 7, Fascicles 27 and 28. Washington, DC, UAS: Armed Forces Institute of Pathology; 1959. p. 32–3.

  2. Zinner MJ, Shurbaji MS, Cameron JL. Solid and papillary epithelial neoplasms of the pancreas. Surgery. 1990;108(3):475–80.

    PubMed  CAS  Google Scholar 

  3. Martin RC, Klimstra DS, Brennan MF, Conlon KC. Solid-pseudopapillary tumor of the pancreas: a surgical enigma? Ann Surg Oncol. 2002;9(1):35–40.

    Article  PubMed  Google Scholar 

  4. Santini D, Poli F, Lega S. Solid-papillary tumors of the pancreas: histopathology. J Pancreas. 2006;7(1):131–6.

    Google Scholar 

  5. Klöppel G, Solcia E, Longnecker DS, Capella C, Sobin LH. Histological typing of tumors of the exocrine pancreas. In: World Health Organization International Histological Classification of Tumors. 2nd ed. New York: Springer; 1996. p. 120–8.

  6. Kaufman SL, Reddick RL, Stiegel M, Wild RE, Thomas CG Jr. Papillary cystic neoplasm of the pancreas: a curable pancreatic tumor. World J Surg. 1986;10(5):851–9.

    Article  PubMed  CAS  Google Scholar 

  7. Learmonth GM, Price SK, Visser AE, Emms M. Papillary and cystic neoplasm of the pancreas—an acinar cell tumour? Histopathology. 1985;9(1):63–79.

    Article  PubMed  CAS  Google Scholar 

  8. Yagihashi S, Sato I, Kaimori M, Matsumoto J, Nagai K. Papillary and cystic tumor of the pancreas. Two cases indistinguishable from islet cell tumor. Cancer. 1988;61(6):1241–7.

    Article  PubMed  CAS  Google Scholar 

  9. Mao C, Guvendi M, Domenico DR, Kim K, Thomford NR, Howard JM. Papillary cystic and solid tumors of the pancreas: a pancreatic embryonic tumor? Studies of three cases and cumulative review of the world’s literature. Surgery. 1995;118(5):821–8.

    Article  PubMed  CAS  Google Scholar 

  10. Klöppel G, Kosmahl M. Cystic lesions and neoplasms of the pancreas. The features are becoming clearer. Pancreatology. 2001;1(6):648–55.

    Article  PubMed  Google Scholar 

  11. Papavramidis T, Papavramidis S. Solid pseudopapillary tumors of the pancreas: review of 718 patients reported in English literature. J Am Coll Surg. 2005;200(6):965–72.

    Article  PubMed  Google Scholar 

  12. Yu PF, Hu ZH, Wang XB, Guo JM, Cheng XD, Zhang YL, et al. Solid pseudopapillary tumor of the pancreas: a review of 553 cases in Chinese literature. World J Gastroenterol. 2010;16(10):1209–14.

    Article  PubMed  Google Scholar 

  13. Ng KH, Tan PH, Thng CH, Ooi LL. Solid pseudopapillary tumour of the pancreas. ANZ J Surg. 2003;73(6):410–5.

    Article  PubMed  Google Scholar 

  14. Potrc S, Kavalar R, Horvat M, Gadzijev EM. Urgent Whipple resection for solid pseudopapillary tumor of the pancreas. J Hepatobiliary Pancreat Surg. 2003;10(5):386–9.

    Article  PubMed  Google Scholar 

  15. Klöppel G, Maurer R, Hofmann E, Lüthold K, Oscarson J, Forsby N, et al. Solid-cystic (papillary-cystic) tumours within and outside the pancreas in men: report of two patients. Virchows Arch A Pathol Anat Histopathol. 1991;418(2):179–83.

    Article  PubMed  Google Scholar 

  16. Kosmahl M, Seada LS, Jänig U, Harms D, Klöppel G. Solid-pseudopapillary tumor of the pancreas: its origin revisited. Virchows Arch. 2000;436(5):473–80.

    Article  PubMed  CAS  Google Scholar 

  17. Fukunaga M. Pseudopapillary solid cystic tumor arising from an extrapancreatic site. Arch Pathol Lab Med. 2001;125(10):1368–71.

    PubMed  CAS  Google Scholar 

  18. Kim YI, Kim ST, Lee GK, Choi BI. Papillary cystic tumor of the liver. A case report with ultrastructural observation. Cancer. 1990;65(12):2740–6.

    Article  PubMed  CAS  Google Scholar 

  19. Nishihara K, Nagoshi M, Tsuneyoshi M, Yamaguchi K, Hayashi I. Papillary cystic tumors of the pancreas. Assessment of their malignant potential. Cancer. 1993;71(1):82–92.

    Article  PubMed  CAS  Google Scholar 

  20. Cappellari JO, Geisinger KR, Albertson DA, Wolfman NT, Kute TE. Malignant papillary cystic tumor of the pancreas. Cancer. 1990;66(1):193–8.

    Article  PubMed  CAS  Google Scholar 

  21. Matsunou H, Konishi F, Yamamichi N, Takayanagi N, Mukai M. Solid, infiltrating variety of papillary cystic neoplasm of the pancreas. Cancer. 1990;65(12):2747–57.

    Article  PubMed  CAS  Google Scholar 

  22. Tang LH, Aydin H, Brennan MF, Klimstra DS. Clinically aggressive solid pseudopapillary tumors of the pancreas: a report of two cases with components of undifferentiated carcinoma and a comparative clinicopathologic analysis of 34 conventional cases. Am J Surg Pathol. 2005;29(4):512–9.

    Article  PubMed  Google Scholar 

  23. González-Cámpora R, Rios Martin JJ, Villar Rodriguez JL, Otal Salaverri C, Hevia Vazquez A, Valladolid JM, et al. Papillary cystic neoplasm of the pancreas with liver metastasis coexisting with thyroid papillary carcinoma. Arch Pathol Lab Med. 1995;19(3):268–73.

    Google Scholar 

  24. Kamei K, Funabiki T, Ochiai M, Amano H, Kasahara M, Sakamoto T. Three cases of solid and cystic tumor of the pancreas. Analysis comparing the histopathological findings and DNA histograms. Int J Pancreatol. 1991;10(3–4):269–78.

    PubMed  CAS  Google Scholar 

  25. Kang CM, Kim HK, Kim H, Choi GH, Kim KS, Choi JS, et al. Expression of Wnt target genes in solid pseudopapillary tumor of the pancreas: a pilot study. Pancreas. 2009;38(2):e53–9.

    Article  PubMed  CAS  Google Scholar 

  26. Lévy P, Bougaran J, Gayet B. Diffuse peritoneal carcinosis of pseudo-papillary and solid tumor of the pancreas. Role of abdominal injury. Gastroenterol Clin Biol. 1997;21(10):789–93.

    PubMed  Google Scholar 

  27. Andronikou S, Moon A, Ussher R. Peritoneal metastatic disease in a child after excision of a solid pseudopapillary tumour of the pancreas: a unique case. Pediatr Radiol. 2003;33(4):269–71.

    PubMed  Google Scholar 

  28. Kyokane T, Iyomasa S, Sawasaki N, Tojima Y, Goto H, Matsuda M, et al. A case of successful resection for peritoneal recurrence of solid-pseudopapillary tumor of the pancreas occurred in 6.5 years after rupture of the tumor. Jpn J Gastroenterol Surg. 2008;41:1815–20.

    Article  Google Scholar 

  29. Rebhandl W, Felberbauer FX, Puig S, Paya K, Hochschorner S, Barlan M, et al. Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children: report of four cases and review of the literature. J Surg Oncol. 2001;76:289–96.

    Article  PubMed  CAS  Google Scholar 

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Conflict of interest

Yoshitsugu Tajima and the other co-authors have no conflicts of interest to declare.

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Authors and Affiliations

  1. Department of Surgery, Nagasaki Municipal Hospital, 6-39 Shinchi, Nagasaki, 850-8555, Japan

    Yoshitsugu Tajima, Norihiro Kohara, Junpei Maeda, Keiji Inoue, Amane Kitasato & Kouji Natsuda

  2. Department of Pathology, Nagasaki Municipal Hospital, 6-39 Shinchi, Nagasaki, 850-8555, Japan

    Junji Irie

  3. Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan

    Tomohiko Adachi, Tamotsu Kuroki, Susumu Eguchi & Takashi Kanematsu

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  1. Yoshitsugu Tajima
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  2. Norihiro Kohara
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Correspondence to Yoshitsugu Tajima.

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Tajima, Y., Kohara, N., Maeda, J. et al. Peritoneal and nodal recurrence 7 years after the excision of a ruptured solid pseudopapillary neoplasm of the pancreas: report of a case. Surg Today 42, 776–780 (2012). https://doi.org/10.1007/s00595-012-0208-7

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  • DOI: https://doi.org/10.1007/s00595-012-0208-7

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