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Ultrasensitive micro ion selective sensor arrays for multiplex heavy metal ions detection

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Abstract

Trace heavy metal ions are probable carcinogens with concentrations at ppb levels. Ion selective electrode (ISE) technology is a conventional and widely used method to detect various ions with the advantages as rapid measurement, low power consumption and low cost. However, the detection limit of a conventional bulky ISE device is only able to reach ppm level so far, not sensitive enough for practically detecting heavy metal ions. A micro ion selective electrode (μISE) array which can realize multiplex detection of heavy metal ions on one chip is reported in this paper. Its detection limit for Pb2+, Cd2+, AsO2−, and Hg2+ can reach 1, 3, 10, and 1 ppb, respectively, within the permissible limits of drinking water. The micrometer scale device arrays from microfabrication processes demonstrated enhanced sensitivity, uniformity, and reduced response time (18 s) compared to conventional ISE. Our devices showed superb selectivity, and the performance dependence on temperature and pH values was investigated as well.

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Authors and Affiliations

  1. State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instruments, Tsinghua University, Beijing, 100084, China

    Rui You, Peng Li & Gaoshan Jing

  2. Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN, 55455, USA

    Tianhong Cui

Authors
  1. Rui You
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  2. Peng Li
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  3. Gaoshan Jing
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  4. Tianhong Cui
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Correspondence to Tianhong Cui.

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You, R., Li, P., Jing, G. et al. Ultrasensitive micro ion selective sensor arrays for multiplex heavy metal ions detection. Microsyst Technol 25, 845–849 (2019). https://doi.org/10.1007/s00542-018-4067-z

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  • DOI: https://doi.org/10.1007/s00542-018-4067-z

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