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Lidocaine spray 10 min prior to intubation: effects on postoperative sore throat

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Abstract

A sore throat is the most frequent adverse side effect of general anesthesia. The purpose of this study was to compare the different types and timing of lidocaine application based on the effectiveness of reducing postoperative sore throat (POST) after endotracheal intubation. In group A, 8% lidocaine was sprayed on laryngopharyngeal structures immediately before intubation, and the distal ends of the endotracheal tubes (ETTs) were lubricated with 2% lidocaine gel. In group B, 8% lidocaine was sprayed, and ETTs were lubricated with normal saline. In groups C and D, no lidocaine was sprayed, and the ETTs were lubricated with normal saline (C, control) or with 2% lidocaine gel (D). In group E, 8% lidocaine was sprayed 10 min prior to endotracheal intubation, and the ETTs were lubricated with normal saline. In 527 patients, 28.2% reported POST at 24 h following extubation. Statistically significant differences in the incidence of POST were found only between group E (16.0%) and each of the other groups (28.4–38.5%), except for group B (26.5%). In conclusion, 8% lidocaine spray significantly reduced the incidence of POST if it was sprayed on laryngopharyngeal structures 10 min prior to endotracheal intubation.

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Notes

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Authors and Affiliations

  1. Division of Surgical Operation Center, Akiru Municipal Medical Center, 78-1 Hikida, Akiruno, Tokyo, 197-0834, Japan

    Kaneatsu Honma

  2. Anesthesiology, Koga Hospital 21, Kurume, Japan

    Masaaki Kamachi

  3. Anesthesiology, Shin Koga Hospital, Kurume, Japan

    Yoshihiko Akamatsu & Masami Yoshioka

  4. Biostatics Center, Kurume University Graduate School of Medicine, Kurume, Japan

    Natsumi Yamashita

Authors
  1. Kaneatsu Honma
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  2. Masaaki Kamachi
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  3. Yoshihiko Akamatsu
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  4. Masami Yoshioka
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  5. Natsumi Yamashita
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Corresponding author

Correspondence to Kaneatsu Honma.

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Honma, K., Kamachi, M., Akamatsu, Y. et al. Lidocaine spray 10 min prior to intubation: effects on postoperative sore throat. J Anesth 24, 962–965 (2010). https://doi.org/10.1007/s00540-010-1013-3

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  • DOI: https://doi.org/10.1007/s00540-010-1013-3

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