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Use of the bispectral index during the early postresuscitative phase after out-of-hospital cardiac arrest

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Abstract

Non-invasive and real-time measures of neurological status after cardiac arrest are needed to be able to make an early determination of the postresuscitative outcome. We investigated whether the bispectral index (BIS) predicts the postresuscitative outcome in 10 patients with out-of-hospital cardiac arrest. We measured the BIS after return of spontaneous circulation (ROSC) in the emergency room and on admission to the intensive care unit (ICU). We determined the Glasgow Coma Scale (GCS) on admission to the emergency room and the ICU and the Glasgow Outcome Scale (GOS) on discharge from the ICU. The BIS increased after about 30 min of ROSC or reached a plateau in patients rated as achieving a good recovery or moderate disability, but it did not increase to >80 in patients rated as being in a permanent vegetative state/dead. The GCS on admission to the ICU was the same as that on admission to the emergency room. The BIS values were significantly lower in the nonsurviving group than in the surviving group. There was a positive correlation between the BIS on admission to the ICU and the GOS on discharge from the ICU. The BIS can thus be used to predict the postresuscitative outcome of patients with out-of-hospital cardiac arrest.

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References

  1. A Mullie P Verstringe W Buylaert H Houbrechts N Michem H Delooz H Verbruggen L Van den Broeck L Corne D Lauwaert (1988) ArticleTitlePredictive values of Glasgow Outcome Score for awaking after out-of-hospital cardiac arrest Lancet 1 137–140

    Google Scholar 

  2. BW Bottiger C Grabner H Bauer C Bode T Weber J Motsch E Martin (1999) ArticleTitleLong-term outcome after out-of-hospital cardiac arrest with physician staffed emergency medical services: the Utsutein style applied to a midsized urban suburban area Heart 52 674–679

    Google Scholar 

  3. RE Westfal S Reissman G Doering (1996) ArticleTitleOut-of-hospital cardiac arrest: an 8-year New York City experience Am J Emerg Med 14 364–368

    Google Scholar 

  4. H Rosen KS Sunnerhagen J Herlitz C Blomstrand L Rosengren (2001) ArticleTitleSerum levels of the brain-derived protein S-100 and NSE predict long-term outcome after cardiac arrest Resuscitation 49 183–191

    Google Scholar 

  5. PS Glass M Bloom L Kearse C Rosow P Sebel P Manberg (1997) ArticleTitleBispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane, and alfentanil in healthy volunteers Anesthesiology 86 836–847

    Google Scholar 

  6. TT Gilbert MR Wagner V Halukurike HL Paz A Garland (2001) ArticleTitleUse of bispectral electroencephalogram monitoring to assess neurological status in unsedated, critically ill patients Crit Care Med 29 1996–2000

    Google Scholar 

  7. R Chen CF Bolton GB Young (1996) ArticleTitlePrediction of outcome in patients with anoxic coma: a clinical and electrophysiologic study Crit Care Med 24 672–678

    Google Scholar 

  8. HJ Theilen M Ragaller U Tscho SA May G Schackert MD Albrecht (2000) ArticleTitleElectroencephalogram silence ratio for early outcome prognosis in severe head trauma Crit Care Med 28 3522–3529

    Google Scholar 

  9. E Edgren U Hedstrand M Nordin E Rydin G Ronquist (1987) ArticleTitlePrediction of outcome after cardiac arrest Crit Care Med 15 820–825

    Google Scholar 

  10. R Flaishon A Windsor J Sigl PS Sebel (1997) ArticleTitleRecovery of consciousness after thiopental or propofol: bispectral index and the isolated forearm technique Anesthesiology 86 613–619

    Google Scholar 

  11. B Vivien S Di Maria A Ouattara O Langeron P Coriat B Riou (2003) ArticleTitleOverestimation of bispectral index in sedated intensive care unit patients revealed by administration of muscle relaxant Anesthesiology 99 9–17

    Google Scholar 

  12. PS Myles S Cairo (2004) ArticleTitleArtifact in the bispectral index in a patient with severe ischemic brain injury Anesth Analg 98 706–707

    Google Scholar 

Download references

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Shibata, S., Imota, T., Shigeomi, S. et al. Use of the bispectral index during the early postresuscitative phase after out-of-hospital cardiac arrest. J Anesth 19, 243–246 (2005). https://doi.org/10.1007/s00540-005-0317-1

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  • DOI: https://doi.org/10.1007/s00540-005-0317-1

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