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Oxidative stress and apoptosis in hepatitis C: the core issue

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References

  1. JM Schattenberg R Singh Y Wang JH Lefkowitch RM Rigoli PE Scherer et al. (2006) ArticleTitleJNK1 but not JNK2 promotes the development of steatohepatitis in mice Hepatology 43 163–72 Occurrence Handle10.1002/hep.20999 Occurrence Handle1:CAS:528:DC%2BD28Xpt1Snsg%3D%3D Occurrence Handle16374858

    Article  CAS  PubMed  Google Scholar 

  2. I Rahman SK Biswas LA Jimenez M Torres HJ Forman (2005) ArticleTitleGlutathione, stress responses, and redox signaling in lung inflammation Antioxid Redox Signal 7 42–59 Occurrence Handle10.1089/ars.2005.7.42 Occurrence Handle1:CAS:528:DC%2BD2MXhsFSlsg%3D%3D Occurrence Handle15650395

    Article  CAS  PubMed  Google Scholar 

  3. K Koike (2005) ArticleTitleMolecular basis of hepatitis C virus-associated hepatocarcinogenesis: lessons from animal model studies Clin Gastroenterol Hepatol 3 S132–5 Occurrence Handle10.1016/S1542-3565(05)00700-7 Occurrence Handle1:CAS:528:DC%2BD2MXhtF2ms73I Occurrence Handle16234061

    Article  CAS  PubMed  Google Scholar 

  4. K Tanikawa (2004) ArticleTitlePathogenesis and treatment of hepatitis C virus-related liver diseases Hepatobiliary Pancreat Dis Int 3 17–20 Occurrence Handle14969831

    PubMed  Google Scholar 

  5. F Farinati R Cardin N De Maria G Della Libera C Marafin E Lecis et al. (1995) ArticleTitleIron storage, lipid peroxidation and glutathione turnover in chronic anti-HCV positive hepatitis J Hepatol 22 449–56 Occurrence Handle10.1016/0168-8278(95)80108-1 Occurrence Handle1:STN:280:ByqA1MritlM%3D Occurrence Handle7545199

    Article  CAS  PubMed  Google Scholar 

  6. A Kitase K Hino T Furutani M Okuda T Gondo I Hidaka et al. (2005) ArticleTitleIn situ detection of oxidized n-3 polyunsaturated fatty acids in chronic hepatitis C: correlation with hepatic steatosis J Gastroenterol 40 617–24 Occurrence Handle10.1007/s00535-005-1596-x Occurrence Handle1:CAS:528:DC%2BD2MXmtVSns70%3D Occurrence Handle16007396

    Article  CAS  PubMed  Google Scholar 

  7. K Moriya K Nakagawa T Santa Y Shintani H Fujie H Miyoshi et al. (2001) ArticleTitleOxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocellular carcinogenesis Cancer Res 61 4365–70 Occurrence Handle1:CAS:528:DC%2BD3MXktlSqu7o%3D Occurrence Handle11389061

    CAS  PubMed  Google Scholar 

  8. M Okuda K Li MR Beard LA Showalter F Scholle SM Lemon et al. (2002) ArticleTitleMitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein Gastroenterology 122 366–75 Occurrence Handle10.1053/gast.2002.30983 Occurrence Handle1:CAS:528:DC%2BD38XhsVGns7o%3D Occurrence Handle11832451

    Article  CAS  PubMed  Google Scholar 

  9. G Gong G Waris R Tanveer A Siddiqui (2001) ArticleTitleHuman hepatitis C virus NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-κB Proc Natl Sci U S A 98 9599–604 Occurrence Handle10.1073/pnas.171311298 Occurrence Handle1:CAS:528:DC%2BD3MXmtlCnur0%3D

    Article  CAS  Google Scholar 

  10. G Vendemiale I Grattagliano P Portincasa G Serviddio G Palasciamo E Altomare (2001) ArticleTitleOxidative stress in symptom-free HCV carriers: relation with ALT flare-up Eur J Clin Invest 31 54–63 Occurrence Handle10.1046/j.1365-2362.2001.00747.x Occurrence Handle1:CAS:528:DC%2BD3MXhsFWls7w%3D Occurrence Handle11168439

    Article  CAS  PubMed  Google Scholar 

  11. A Ruggieri T Harada Y Matsuura T Miyamura (1997) ArticleTitleSensitization to Fas-mediated apoptosis by hepatitis C virus core protein Virology 229 68–76 Occurrence Handle10.1006/viro.1996.8420 Occurrence Handle1:CAS:528:DyaK2sXhs1KhtL8%3D Occurrence Handle9123879

    Article  CAS  PubMed  Google Scholar 

  12. RB Ray K Meyer R Steele A Shrivastava BB Aggarwal R Ray (1998) ArticleTitleInhibition of tumor necrosis factor (TNF-α)-mediated apoptosis by hepatitis C virus core protein J Biol Chem 273 2256–9 Occurrence Handle10.1074/jbc.273.4.2256 Occurrence Handle1:CAS:528:DyaK1cXnsVKrtg%3D%3D Occurrence Handle9442069

    Article  CAS  PubMed  Google Scholar 

  13. N Zhu A Khoshnan R Schneider M Matsumoto G Dennert C Ware et al. (1998) ArticleTitleHepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis J Virol 72 3691–7 Occurrence Handle1:CAS:528:DyaK1cXis1Kgu7s%3D Occurrence Handle9557650

    CAS  PubMed  Google Scholar 

  14. H Marusawa M Hijikata T Chiba K Shimotohno (1999) ArticleTitleHepatitis C virus core protein inhibits Fas- and tumor necrosis factor α-mediated apoptosis via NF-κB activation J Virol 73 4713–20 Occurrence Handle1:CAS:528:DyaK1MXjtFert7s%3D Occurrence Handle10233931

    CAS  PubMed  Google Scholar 

  15. A Macdonald M Harris (2004) ArticleTitleHepatitis C virus NS5A: tales of a promiscuous protein J Gen Virol 85 2485–502 Occurrence Handle10.1099/vir.0.80204-0 Occurrence Handle1:CAS:528:DC%2BD2cXnsVegsr4%3D Occurrence Handle15302943

    Article  CAS  PubMed  Google Scholar 

  16. Y Hara K Hino M Okuda T Furutani I Hidaka Y Yamaguchi et al. (2006) ArticleTitleHepatitis C virus core protein inhibits deoxycholic acid-mediated apoptosis despite generating mitochondrial reactive oxygen species J Gastroenterol 41 257–68

    Google Scholar 

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Koike, K. Oxidative stress and apoptosis in hepatitis C: the core issue. J Gastroenterol 41, 292–294 (2006). https://doi.org/10.1007/s00535-006-1786-1

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