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The effect of demographic, clinical, and pathological data on quality of life in rectum cancer

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Abstract

Purpose

The aims of the current study are to describe the quality of life among patients with rectal cancer and to determine the clinical and demographic correlation that influences the quality of life of rectal cancer patients.

Method

In this study, 50 patients with rectal cancer treated in the Radiation Oncology Department of Kayseri City Education and Research Hospital were included. Ethics committee approval was received for the study. Data collection form was used to determine the demographic and clinicopathological characteristics of the patients. To assess the quality of life, the European Committee of Cancer Treatment and Organization Quality of Life Scale (EORTC QLQ-C30) question–answer scale was used. The data were collected by interviewing the patients face to face. Mann–Whitney U and Kruskal–Wallis tests were used to analyze the data. Spearman correlation analysis was performed to reveal the relationship between dependent variables.

Results

As a result of this study, 52% of patients were 65 years and older and 54% were male patients. The most common surgery was low anterior resection and the most common type of pathology was adenocarcinoma. According to American Cancer Committee (AJCC) 7th edition 2009 staging, 80% stage 3 was the most common. In EORTC C30 Cancer Quality of Life Scale Functional Scale Subscale, the highest score is from the physical function and the lowest score is from the emotional function. In the symptom scale subscale, the most common symptom was nausea/vomiting. Performance status (ECOG) was found to be significantly associated with T stage, N stage, TNM stage, and symptom scores. There was a moderately significant positive correlation between symptom scales and global health status scales (ρ = 0.51; p < 0.001). There was a perfectly positive and significant relationship between symptom scales and functional scales (ρ = 0.83; p < 0.001).

Conclusions

As a result of this study we conducted, it was observed that rectal cancer patients decreased performance status and increased symptoms in the presence of advanced disease. Accordingly, it was found that the quality of life of the patient decreased.

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Data availability

The authors have full control of the data, and data is available upon request.

Code availability

Analyses were performed with SPSS 18 (IBM Corp., Armonk, NY, USA).

References

  1. Cohen S, Bordeianou L. continued improvement in rectal cancer survival outcomes will require true multidisciplinary treatment approaches J Gastrointest Surg. 2019 Dec 17. https://doi.org/10.1007/s11605-019-04461-0

  2. Jemal A, Siegel R, Ward E et al (2008) Cancer statistics, 2008. CA Cancer J Clin 58:71

    Article  Google Scholar 

  3. Aykan NF, Yalçın Ş, Turhal NS, Özdoğan M, Demir G et al (2015) Epidemiology of colorectal cancer in Turkey: a cross-sectional disease registry study (A Turkish Oncology Group trial). Turk J Gastroenterol 26(2):145–53

    Article  Google Scholar 

  4. São Julião GP, Habr-Gama A, Vailati BB, Araujo SEA, Fernandez LM, Perez RO (2017) Surg Clin North Am. New Strategies in Rectal Cancer 97(3):587–604. https://doi.org/10.1016/j.suc.2017.01.008

    Article  Google Scholar 

  5. Gujral S, Conroy T, Fleissner C, Sezer O, King PM, Avery KN, Sylvester P, Koller M, Sprangers MA, Blazeby JM, European Organisation for Research and Treatment of Cancer Quality of Life Group (2007) Assessing quality of life in patients with colorectal cancer: an update of the EORTC quality of life questionnaire. Eur J Cancer 43(10):1564–73

    Article  CAS  Google Scholar 

  6. Du P, Wang SY, Zheng PF, Mao J, Hu H, Cheng ZB (2019) Comparison of overall survival and quality of life between patients undergoing anal reconstruction and patients undergoing traditional lower abdominal stoma after radical resection. Clin Transl Oncol 21(10):1390–1397. https://doi.org/10.1007/s12094-019-02106-x

    Article  CAS  PubMed  Google Scholar 

  7. Santos LJ, Garcia JB, Pacheco JS, Vieira EB, Santos AM (2014) Quality of life, pain, anxiety and de pression in patients surgically treated with cancer of rectum. Arq Bras Cir Dig 27(2):96–100 (English, Portuguese)

    Article  Google Scholar 

  8. Pieniowski EHA, Palmer GJ, Juul T, Lagergren P, Johar A, Emmertsen KJ, Nordenvall C, Abraham-Nordling M (2019) Low anterior resection syndrome and quality of life after sphincter-sparing rectal cancer surgery: a long-term longitudinal follow-up. Dis Colon Rectum 62(1):14–20. https://doi.org/10.1097/DCR.0000000000001228

    Article  PubMed  Google Scholar 

  9. Saegrov S (2005) Health, Quality of Life and Cancer. Int Nurs Rev 52:233–240

    Article  CAS  Google Scholar 

  10. Greimel ER, Padilla G, Grant MM (1998) Gender Differences in Outcomes Among Patients with Cancer. Psychooncology 1998(7):197–206

    Article  Google Scholar 

  11. Arraras JI, Suárez J, Arias-de-la-Vega F, Vera R, Ibáñez B, Asin G, Viudez A, Zarandona U, Rico M, Hernández I (2013) Quality of life assessment by applying EORTC questionnaires to rectal cancer patients after surgery and neoadjuvant and adjuvant treatment. Rev Esp Enferm Dig 105(5):255–61

    Article  Google Scholar 

  12. Wang L, Wang X, Lo A, Raval M, Brown C, Karimuddin A, Phang PT (2018) Effects of radiation and surgery on function and quality of life (QOL) in rectal cancer patients. Am J Surg 215(5):863–866. https://doi.org/10.1016/j.amjsurg.2018.01.014

    Article  PubMed  Google Scholar 

  13. Pucciarelli S, Giandomenico F, De Paoli A, Gavaruzzi T, Lotto L, Mantello G, Barba C, Zotti P, Flora S, Del Bianco P (2017) Bowel function and quality of life after local excision or total mesorectal excision following chemoradiotherapy for rectal cancer. Br J Surg 104(1):138–147. https://doi.org/10.1002/bjs.10318

    Article  CAS  PubMed  Google Scholar 

  14. Güzelant A, Göksel T, Özkök S et al (2004) The European Organization for Research and Treatment of Cancer QLQ-C30: an examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. Eur J Cancer Care 13:135–144

    Article  Google Scholar 

  15. Rustoen T, Moum T, Wiklund I, Hanestad BR (1999) Quality of Life in Newly Diagnosed Cancer Patients. J Adv Nurs 29(2):490–498

    Article  CAS  Google Scholar 

  16. Ferrell B, Cullinane CA, Ervin K, Melancon C, Uman GC, Juarez G (2005) Perspectives on the Impact of Ovarian Cancer: Women’s Views of Quality of Life. Oncol Nurs Forum 32(6):1143–1149

    Article  Google Scholar 

  17. Mrabti H, Amziren M, ElGhissassi I, Bensouda Y, Berrada N, Abahssain H, Boutayeb S, El Fakir S, Nejjari C, Benider A, Mellas N, El Mesbahi O, Bennani M, Bekkali R, Zidouh A, Errihani H (2016) Quality of life of early stage colorectal cancer patients in Morocco. BMC Gastroenterol 16(1):131

    Article  Google Scholar 

  18. Couwenberg AM, Burbach JPM, van Grevenstein WMU, Smits AB, Consten ECJ, Schiphorst AHW, Wijffels NAT, Heikens JT, Intven MPW, Verkooijen HM (2018) Effect of Neoadjuvant Therapy and Rectal Surgery on Health-related Quality of Life in Patients With Rectal Cancer During the First 2 Years After Diagnosis. Clin Colorectal Cancer 17(3):e499–e512. https://doi.org/10.1016/j.clcc.2018.03.009

    Article  PubMed  Google Scholar 

  19. Wilson TR, Alexander DJ (2008) Clinical and non-clinical factors influencing postoperative health-related quality of life in patients with colorectal cancer. Br J Surg 2008(95):1408–1415

    Article  Google Scholar 

  20. Wiltink LM, Nout RA, van der Voort van Zyp JR, Ceha HM, Fiocco M, Meershoek-Klein Kranenbarg E, Marinelli AW, van de Velde CJ, Marijnen CA. Long-Term Health-Related Quality of Life in Patients With Rectal Cancer After Preoperative Short-Course and Long-Course (Chemo) Radiotherapy. Clin Colorectal Cancer. 2016 Sep;15(3):e93-9. https://doi.org/10.1016/j.clcc.2016.02.012. Epub 2016 Feb 13

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Authors and Affiliations

  1. Department of Radiation Oncology, Kayseri City Education and Research Hospital, Muhsinyazıcıoğlu Boulevard, No: 77, 38080, Şeker District, Kocasinan/Kayseri, Turkey

    Yasemin Benderli Cihan

  2. Department of Biostatistics, Erciyes University Faculty of Medicine, Kayseri, Turkey

    Ahmet Ozturk

Authors
  1. Yasemin Benderli Cihan
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  2. Ahmet Ozturk
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Correspondence to Yasemin Benderli Cihan.

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The study was approved by Erciyes University Medical Research Ethics.

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Cihan, Y.B., Ozturk, A. The effect of demographic, clinical, and pathological data on quality of life in rectum cancer. Support Care Cancer 29, 7411–7420 (2021). https://doi.org/10.1007/s00520-021-06300-y

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