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Traction with dental floss and endoscopic clip improves trainee success in performing gastric endoscopic submucosal dissection (ESD): a live porcine study (with video)

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Abstract

Background and aims

Endoscopic submucosal dissection (ESD) is a prolonged procedure with serious adverse events. The clip with line traction method was reported to improve ESD. However, there was no comparison with conventional ESD especially for trainees. We report here on the feasibility and efficacy of traction using dental floss with endoscopic clip to facilitate ESD versus conventional method for ESD trainees.

Methods

Twenty simulated gastric lesions, paired with location and size, were created in porcine stomachs using a standard template. After a circular incision was made, submucosal dissection (control, n = 10) was performed with standard ESD, while the study (clip, n = 10) was performed with traction using dental floss and endoclip. Primary outcome was speed of submucosal dissection. Secondary outcome included frequency of submucosal injection and adverse event.

Results

Compared with controls, median procedure time was significantly shorter in the clip group (5.6 ± 1.1 vs. 13.6 ± 2.5 min, P = 0.003), with a significantly faster submucosal dissection time (1.8 ± 0.3 vs. 0.6 ± 0.1 cm2/min, P = 0.001) and less frequent submucosal injection (5.7 ± 0.6 vs. 8.5 ± 1.0 times, P = 0.024). There were no perforations in either group, but less adverse events (bleeding and injury to muscularis propria) in the clip group (1 vs. 7, P = 0.068, α = 0.1).

Conclusions

Traction provided by dental floss and endoclip improves visualization of the submucosal layer during ESD. It allows a faster and safer gastric ESD especially among trainees in the early learning phase.

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Acknowledgments

This work was supported by the Special Research Found for Health Care of PLA, China (Grant No. 12BJZ04).

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Authors and Affiliations

  1. Department of Gastroenterology, Beijing Military General Hospital, Nanmenchang 5#, Dongcheng District, Beijing, 100700, China

    Yuqi He, Kuangi Fu, Peng Jin, Yang Yu, Dongliang Yu, Xin Wang & Jianqiu Sheng

  2. Section of Gastroenterology, Sacramento VA Medical Center, Sacramento, CA, USA

    Joseph Leung

  3. Department of Science, Tianjin University of Commerce, Tianjin, 300134, China

    Yongqiang Du

  4. Institute for Translational Medicine, College of Medicine, Qingdao University, Qingdao, 266021, China

    Jianxun Wang

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  1. Yuqi He
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  2. Kuangi Fu
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  3. Joseph Leung
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  5. Jianxun Wang
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  7. Yang Yu
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  9. Xin Wang
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  10. Jianqiu Sheng
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Correspondence to Jianqiu Sheng.

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Disclosures

Drs. Yuqi He, Kuangi Fu, Joseph Leung, Yongqiang Du, Jianxun Wang, Peng Jin, Yang Yu, Dongliang Yu, Xin Wang, Hui Xie, and Jianqiu Sheng have no conflict of interests or financial ties to disclose.

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He, Y., Fu, K., Leung, J. et al. Traction with dental floss and endoscopic clip improves trainee success in performing gastric endoscopic submucosal dissection (ESD): a live porcine study (with video). Surg Endosc 30, 3138–3144 (2016). https://doi.org/10.1007/s00464-015-4598-7

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  • DOI: https://doi.org/10.1007/s00464-015-4598-7

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