Skip to main content
SpringerLink
Log in

Early results of a randomized multicenter trial comparing Prolene and VyproII mesh in bilateral endoscopic extraperitoneal hernioplast (TEP)

  • Original article
  • Published:
Surgical Endoscopy And Other Interventional Techniques Aims and scope Submit manuscript

Abstract

Background

The use of mesh in inguinal hernia surgery has become increasingly popular despite the potentially harmful effects that foreign material may exert on human tissue. The purpose of this study was to compare the use of a lightweight mesh vs a standard hernia mesh in bilateral endoscopic hernioplasty.

Methods

This single-blinded multicenter trial, 140 men with bilateral inguinal hernias were randomized to undergo totally extraperitoneal endoscopic hernioplasty (TEP) with either Prolene or VyproII. The randomization and all data management were done via the Internet.

Results

A total of 139 patients were operated on as allocated. The follow-up was complete in 94% of the patients. The median (range) operating times were 85 min (45-140) and 73min (35-165) for the Prolene and VyproII groups, respectively. (p = 0.01). The difference was due to uneven distribution of the allocated patients to study groups among individual surgeons. The time to return to work was similar (11 vs 9 days, p = 0.08). The time to return to normal daily activities was 19 days (1-133) in the Prolene group and 12.5 days (0-237) in the VyproII group (p = 0.06). There were no significant differences between the groups in their scores on the Visual Analogue Scale or SF-36 Health Scores during the 8-week follow-up.

Conclusions

The use of Prolene and VyproII meshes in bilateral endoscopic repair of inguinal hernia seems to result in similar short-term outcome and quality of life. However, there was a tendency toward faster return to normal activity among VyproII patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1
Figure 2

Similar content being viewed by others

References

  1. M Bay-Nielsen H Kehlet L Strand J Malmstrom FH Andersen P Wara P Juul et al. (2001) ArticleTitleQuality assessment of 26,304 herniorrhaphies in Denmark: a prospective nationwide study Lancet 358 1124–1128 Occurrence Handle10.1016/S0140-6736(01)06251-1 Occurrence Handle1:STN:280:DC%2BD3MrltFOmtQ%3D%3D Occurrence Handle11597665

    Article  CAS  PubMed  Google Scholar 

  2. Bringman S, Heikkinen T, Wollert S, Osterberg J, Smedberg S, Granlund H, Ramel S, et al. (2004) Early results of a single-blinded, randomized, controlled, Internet-based multicenter trial comparing Prolene and VyproII mesh in Lichtenstein hernioplasty. Hernia. Online first 8: 127–134

    Google Scholar 

  3. S Bringman S Wollert T Osterberg S Smedberg H Granlund G Fellander T Heikkinen (2004) ArticleTitleOne year results of a single-blinded, randomised, controlled, Internet-based multi-centre trial comparing Prolene and VyproII-mesh in Lichtenstein hernioplasty Br J Surg . .

    Google Scholar 

  4. T Callesen K Bech J Andersen R Nielsen O Roikjaer H Kehlet (1999) ArticleTitlePain after primary inguinal herniorrhaphy: influence of surgical technique J Am Coll Surg 188 355–359 Occurrence Handle10.1016/S1072-7515(98)00316-0 Occurrence Handle1:STN:280:DyaK1M3htVSqsQ%3D%3D Occurrence Handle10195718

    Article  CAS  PubMed  Google Scholar 

  5. EH Collaboration (2000) ArticleTitleMesh compared with non-mesh methods of open groin hernia repair: systematic review of randomized controlled trials Br J Surg 87 854–859 Occurrence Handle10.1046/j.1365-2168.2000.01539.x Occurrence Handle1:STN:280:DC%2BD3cvgtFynug%3D%3D Occurrence Handle10931018

    Article  CAS  PubMed  Google Scholar 

  6. EH Collaboration (2000) ArticleTitleLaparoscopic compared with open methods of groin hernia repair: systematic review of randomized controlled trials Br J Surg 87 860–867 Occurrence Handle10.1046/j.1365-2168.2000.01540.x Occurrence Handle1:STN:280:DC%2BD3cvgtFynuw%3D%3D Occurrence Handle10931019

    Article  CAS  PubMed  Google Scholar 

  7. AM Grant (2002) ArticleTitleLaparoscopic versus open groin hernia repair: meta-analysis of randomised trials based on individual patient data Hernia 6 2–10 Occurrence Handle1:STN:280:DC%2BD38zks12isA%3D%3D Occurrence Handle12090575

    CAS  PubMed  Google Scholar 

  8. CP Heise JR Starling (1998) ArticleTitleMesh inguinodynia: a new clinical syndrome after inguinal herniorrhaphy? J Am Coll Surg 187 514–518 Occurrence Handle10.1016/S1072-7515(98)00215-4 Occurrence Handle1:STN:280:DyaK1M%2FisFChsA%3D%3D Occurrence Handle9809568

    Article  CAS  PubMed  Google Scholar 

  9. K Junge U Klinge A Prescher P Giboni M Niewiera V Schumpelick (2001) ArticleTitleElasticity of the anterior abdominal wall and impact for reparation of incisional hernias using mesh implants Hernia 5 113–118 Occurrence Handle10.1007/s100290100019 Occurrence Handle1:STN:280:DC%2BD38%2Fjt1ehtA%3D%3D Occurrence Handle11759794

    Article  CAS  PubMed  Google Scholar 

  10. K Junge U Klinge R Rosch B Klosterhalfen V Schumpelick (2002) ArticleTitleFunctional and morphologic properties of a modified mesh for inguinal hernia repair World J Surg 26 1472–1480 Occurrence Handle10.1007/s00268-002-6444-z Occurrence Handle12297937

    Article  PubMed  Google Scholar 

  11. U Klinge B Klosterhalfen M Muller M Anurov A Ottinger V Schumpelick (1999) ArticleTitleInfluence of polyglactin-coating on functional and morphological parameters of polypropylene-mesh modifications for abdominal wall repair Biomaterials 20 613–623 Occurrence Handle10.1016/S0142-9612(98)00211-7 Occurrence Handle1:STN:280:DyaK1M3itlSrtg%3D%3D Occurrence Handle10208403

    Article  CAS  PubMed  Google Scholar 

  12. U Klinge B Klosterhalfen M Muller V Schumpelick (1999) ArticleTitleForeign body reaction to meshes used for the repair of abdominal wall hernias Eur J Surg 165 665–673 Occurrence Handle10.1080/11024159950189726 Occurrence Handle1:STN:280:DyaK1MznvFegsg%3D%3D Occurrence Handle10452261

    Article  CAS  PubMed  Google Scholar 

  13. BF Matlaga TN Salthouse (1983) ArticleTitleUltrastructural observations of cells at the interface of a biodegradable polymer: Polyglactin 910 J Biomed Mater Res 17 185–197 Occurrence Handle10.1002/jbm.820170115 Occurrence Handle1:CAS:528:DyaL3sXhtFeltLY%3D Occurrence Handle6826574

    Article  CAS  PubMed  Google Scholar 

  14. AS Poobalan J Bruce WC Smith PM King ZH Krukowski WA Chambers (2003) ArticleTitleA review of chronic pain after inguinal herniorrhaphy Clin J Pain 19 48–54 Occurrence Handle10.1097/00002508-200301000-00006 Occurrence Handle12514456

    Article  PubMed  Google Scholar 

  15. S Post B Weiss M Wilier T Neufang D Lorenz (2004) ArticleTitleRandomized clinical trial of lightweight composite mesh for Lichtenstein inguinal hernia repair Br J Surg 91 44–48 Occurrence Handle10.1002/bjs.4387 Occurrence Handle1:STN:280:DC%2BD2c%2FhvVWiug%3D%3D Occurrence Handle14716792

    Article  CAS  PubMed  Google Scholar 

  16. Sullivan, M, Karlsson, J (1994) SF-36 Halsoenkat Manual och tolkningsguide, Sektionen for vardforskning, Sahlgrenska sjukhuset, Goteborg, Sweden

  17. M Sullivan J Karlsson (1998) ArticleTitleThe Swedish SF-36 Health Survey III. Evaluation of criterion-based validity: results from normative population J Clin Epidemiol 51 1105–1113 Occurrence Handle10.1016/S0895-4356(98)00102-4 Occurrence Handle1:STN:280:DyaK1M%2Fjt1Siug%3D%3D Occurrence Handle9817128

    Article  CAS  PubMed  Google Scholar 

  18. G Welty U Klinge B Klosterhalfen R Kasperk V Schumpelick (2001) ArticleTitleFunctional impairment and complaints following incisional hernia repair with different polypropylene meshes Hernia 5 142–147 Occurrence Handle10.1007/s100290100017 Occurrence Handle1:STN:280:DC%2BD38%2Fjt1egsA%3D%3D Occurrence Handle11759800

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgment

The study was supported by grants from Ethicon Scandinavia, Ethicon Europe, and the County Council of Stockholm. We are grateful to Cajsa Barthelsson, R.N.; Christina Lindblom, R.N.; and Sirpa Jamsa, R.N. as well as secretary. Lise-Lotte Lindh, for their skillful work.

Author information

Authors and Affiliations

  1. Center for Surgical Sciences, Karolinska Institutet, Sodertalje Hospital, SE-15286, Sodertalje, Sweden

    S. Bringman

  2. Department of Surgery, Uppsala University Hospital, 75185 Uppsala, Sweden

    S. Wollert

  3. Department of Surgery, Mora Hospital, 79285 Mora, Sweden

    J. Osterberg

  4. Department of Surgery, Oulu University Hospital, 90021 OYS Oulu, PL21 Finland

    T. Heikkinen

Authors
  1. S. Bringman
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Wollert
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. Osterberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. T. Heikkinen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. Bringman.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bringman, S., Wollert, S., Osterberg, J. et al. Early results of a randomized multicenter trial comparing Prolene and VyproII mesh in bilateral endoscopic extraperitoneal hernioplast (TEP). Surg Endosc 19, 536–540 (2005). https://doi.org/10.1007/s00464-004-9100-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00464-004-9100-x

Keywords

Search

Navigation