Abstract
Four children under 16 months of age presented within an 18-month period with severe, rapidly progressive Panton–Valentine leukocidin-associated ST93 Staphylococcus aureus necrotizing pneumonia. Two of the cases that required extracorporeal membranous oxygenation and proved fatal had poor prognostic features of leukopaenia, rash and pulmonary haemorrhage. All four cases had recent contact with S. aureus infection in a family member. Reported cases of S. aureus necrotizing pneumonia in infants are reviewed, and approach to management is discussed.
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Acknowledgements
We would like to thank the paediatric and intensive care teams for their tremendous work and dedication in managing these cases, as well as the families of these patients for generously sharing their details.
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The authors have no conflicts of interest and did not receive any funding for this study.
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Schwartz, K.L., Nourse, C. Panton–Valentine leukocidin-associated Staphylococcus aureus necrotizing pneumonia in infants: a report of four cases and review of the literature. Eur J Pediatr 171, 711–717 (2012). https://doi.org/10.1007/s00431-011-1651-y
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DOI: https://doi.org/10.1007/s00431-011-1651-y