Abstract
The aim of this study was to examine the occurrence of end-stage renal disease (ESRD) in Slovak children, to compare it with earlier Slovak data and with data from other European countries, and to explore etiology. Over the years 2003–2009, data on the incidence and prevalence of all cases of ESRD in children from all four Slovak tertiary pediatric centers were collected. The data were compared with two earlier Slovak studies and with European data from the European Society of Paediatric Nephrology. The median annual incidence rate of ESRD in Slovak children under 15 years of age was 6.6 per million age-related population (pmarp). The prevalence rate on 31 December 2009 was 24.1 pmarp. Compared with the last study (18.6 pmarp), the differences were not statistically significant. The comparison with neighboring countries and with the European average shows no significant difference in incidence, while prevalence is significantly lower compared to neighboring Austria and some other (mostly western) European countries as well as the European average. In conclusion, during the past decade, the incidence and prevalence rates of ESRD in Slovak children have remained stable. Compared to the European average, the prevalence in Slovak children is significantly lower.
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Ardissino G, Dacco V, Testa S, Bonaudo R, Claris-Appiani A, Taioli E, Marra G, Edefonti A, Sereni F, ItalKid Project (2003) Epidemiology of chronic renal failure in children: data from the ItalKid project. Pediatrics 111:e382–e387
Briggs JD (2000) The ERA-EDTA Registry returns to Amsterdam. Nephrol Dial Transplant 15:1326–1327
British Association for Paediatric Nephrology (2005) Report from the paediatric renal registry. In: Ansell D, Feest TG (eds) The UK Renal Registry 8th Annual Report, pp 269–291
ERA-EDTA Registry (2008) ERA-EDTA Registry 2006 annual report. Academic Medical Center, Department of Medical Informatics, Amsterdam
ESPN/ERA-EDTA Registry (2009) ESPN/ERA-EDTA Registry 2007 annual report. Academic Medical Center, Department of Medical Informatics, Amsterdam
ESPN/ERA-EDTA Registry (2010) ESPN/ERA-EDTA Registry 2008 annual report. Academic Medical Center, Department of Medical Informatics, Amsterdam
Lewis MA, Shaw J, Sinha MD, Adalat S, Hussain F, Castledine C, van Schalkwyk D, Inward C (2010) UK Renal Registry 12th annual report (December 2009): chapter 14: demography of the UK paediatric renal replacement therapy population in 2008. Nephron Clin Pract 115(Suppl 1):c279–c288
Mehls O, Rigden S, Ehrich JH, Berthoux F, Jones EH, Valderrabano F (1996) Report on management of renal failure in Europe, XXV, 1994. The child-adult interface. The EDTA-ERA Registry. European Dialysis and Transplant Association-European Renal Association. Nephrol Dial Transplant 11(Suppl 1):22–36
NAPRTCS (2007) North American Pediatric Renal Trials and Collaborative Studies 2007. http://www.emmes.com/study/ped/annlrept/annlrept2007.pdf. Accessed 2 Nov 2011
Podracka L, Kovacs L (2004) Epidemiologia chronickej renalnej insuficiencie u deti na Slovensku. (Epidemiology of chronic renal insufficiency in children in Slovakia). Cesk Pediatr 7:331
Reiss U, Wingen AM, Scharer K (1996) Mortality trends in pediatric patients with chronic renal failure. Pediatr Nephrol 10:41–45
U.S. Renal Data System (2005) USRDS 2005 Annual Data Report: Atlas of End-stage renal disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda
van der Heijden BJ, van Dijk PC, Verrier-Jones K, Jager KJ, Briggs JD (2004) Renal replacement therapy in children: data from 12 registries in Europe. Pediatr Nephrol 19:213–221
van Stralen KJ, Tizard EJ, Verrina E, Schaefer F, Jager KJ, European Society for Paediatric Nephrology/European Renal Association-European Dialysis and Transplant Association (ESPN/ERA-EDTA) registry study group (2010) Demographics of paediatric renal replacement therapy in Europe: 2007 annual report of the ESPN/ERA-EDTA registry. Pediatr Nephrol 25:1379–1382
Warady BA, Chadha V (2007) Chronic kidney disease in children: the global perspective. Pediatr Nephrol 22:1999–2009
Zurowska A, Zagozdzon I, Balasz I, Boguszewska A, Prokurat C, Pietrzyk J, Drozdz D, Szczepanska M, Stefaniak E, Jander A, Roszkowska-Blaim D, Ziolkowska H, Makulska I, Kollataj B, Jarmolinski T, Siten G, Stankiewicz R, Wiercinski R (2006) Congenital and genetic related causes of end-stage renal disease—data from Polish Registry of Renal Replacement Therapy in Children 2000–2004. Przegl Lek 63(Suppl 3):57–59
Zvara V, Sasinka M, Pribylincova V, Kaiserova E, Borosova E, Reznicek J (1978) Epidemiology of chronic renal insufficiency in children in Slovakia. Cesk Pediatr 33:321–325
Acknowledgments
The authors would like to thank all participating centers for their invaluable contribution to the data collection: Z. Kizekova MD, Bratislava; M. Dluholucky MD, Banska Bystrica; and M. Antonyova MD, Martin. This work was supported by the Slovak Research and Development Agency under contract no. APVV-20-038305. This work was also supported by the project “Centre for Excellent Research of Atherosclerosis and its Complications—Myocardial Infarction and Stroke,” Operational Program of Research and Development financed by the European Fund for Regional Development.
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A list of the participating centers is provided in the Acknowledgements.
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Kolvek, G., Reijneveld, S.A., Podracka, L. et al. End-stage renal disease in Slovak children: epidemiology from a European perspective. Eur J Pediatr 170, 1445–1451 (2011). https://doi.org/10.1007/s00431-011-1462-1
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DOI: https://doi.org/10.1007/s00431-011-1462-1