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Thymoma with ganglioneuroblastomatous component: case report

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Abstract

A mediastinal tumor in a 49-year-old woman with myasthenia gravis is reported. The tumor was well-demarcated and located in the supero-anterior mediastinum. Microscopically, the tumor consisted of thymic and neuroblastic tumor components, the latter of which consisted of immature and maturing neuronal cells, abundant neuropils, and Schwannian stroma. The two components intermingled with each other inside the tumor capsule. The tumor was diagnosed as thymoma with a ganglioneuroblastomatous component. The coexistence of epithelial and neuronal tissues in the thymic neoplasm is extremely rare.

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Acknowledgements

The authors thank Miss Kaori Satoh (Department of Pathology, Gunma University Hospital) for her technical and clerical assistance.

Conflict of interest statement

We declare that we have no conflicts of interest.

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Authors and Affiliations

  1. Department of Clinical Pathology, Saiseikai Maebashi Hospital, 564-1 Kamishinden-machi, Maebashi, Gunma, 371-0821, Japan

    Kenji Kashiwabara

  2. Department of Clinical Pathology, Fukaya Red Cross Hospital, Fukaya, Japan

    Hayato Ikota

  3. Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan

    Shigebumi Tanaka, Chie Ohta, Toshiki Yajima, Hideki Endoh, Ei Yamaki & Hiroyuki Kuwano

  4. Department of Pathology, Gunma University Hospital, Maebashi, Japan

    Takashi Nakajima

Authors
  1. Kenji Kashiwabara
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  2. Hayato Ikota
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  3. Shigebumi Tanaka
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  4. Chie Ohta
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  5. Toshiki Yajima
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  6. Hideki Endoh
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  7. Ei Yamaki
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  8. Hiroyuki Kuwano
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  9. Takashi Nakajima
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Correspondence to Kenji Kashiwabara.

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Kashiwabara, K., Ikota, H., Tanaka, S. et al. Thymoma with ganglioneuroblastomatous component: case report. Virchows Arch 452, 319–324 (2008). https://doi.org/10.1007/s00428-007-0544-y

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  • DOI: https://doi.org/10.1007/s00428-007-0544-y

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