Abstract
Purpose
The aim of this study was to examine the effects of persulphate on the nasal mucosa and on the immune cells in hairdressers suffering from bleaching powder associated rhinitis (BAR) versus subjects with rhinitis not previously exposed to bleaching powder.
Methods
Fifteen hairdressers (S) with BAR, 14 without symptoms (WS) and 12 atopics (A) with rhinitis but without exposure to bleaching powder were studied. Each performed a nasal challenge with persulphates. Effect parameters were symptom score, acoustic rhinometry, albumin in nasal lavage, subpopulations of lymphocytes in blood and specific serum antibodies.
Results
The S group had a post-challenge increase in nasal symptoms and nasal lavage albumin. The A group reacted to a lesser intent. The S and A groups showed an increase in Th1 cells. An HLA class II cell expression was noticed in both groups of hairdressers. No evidence of a type 1 reaction (immediate type) to persulphate was noticed.
Conclusions
Persulphate challenge affects hairdressers with BAR, but also atopics. The reaction may be driven by a Th1 cell activation.
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References
Aalto-Korte K, Mäkinen-Kiljunen S (2003) Specific immunoglobulin E in patients with immediate persulfate hypersensitivity. Contact Dermatitis 49:22–25. doi:10.1111/j.0105-1873.2003.00134.x
Aas K, Belin L (1973) Standardization of diagnostic work in allergy. Int Arch Allergy 45:57–60
Albin M, Rylander L, Mikoczy Z, Lillienberg L, Dahlman Höglund A, Brisman J et al (2002) The incidence of asthma in female Swedish hairdressers. Occup Environ Med 59:119–123. doi:10.1136/oem.59.2.119
Andersson M, Kogerer BV, Andersson P, Pipkorn U (1987) Allergen-induced nasal hyperreactivity appears unrelated to the size of the nasal and dermal immediate allergic reaction. Allergy 42:631–637. doi:10.1111/j.1398-9995.1987.tb00395.x
Banauch GI, Dhala A, Prezant DJ (2005) Pulmonary disease in rescue workers at the World Trade Center site. Curr Opin Pulm Med 11(2):160–168. doi:10.1097/01.mcp.0000151716.96241.0a
Brisman J, Albin M, Rylander L, Mikoczy Z, Lillienberg L, Höglund AD et al (2003) The incidence of respiratory symptoms in female Swedish hairdressers. Am J Ind Med 44(6):673–678. doi:10.1002/ajim.10293
Hilberg O, Pedersen OF (2000) Acoustic rhinometry: recommendations for technical specifications and standard operating procedures. Rhinol Suppl 16:3–17
Hollund BE, Moen BE, Egeland GM, Florvaag E (2002) Occupational exposure to hairdressing chemicals and immunoglobulin E synthesis. Scand J Work Environ Health 28:264–269
Hytönen M, Leino T, Sala E, Kanerva L, Tupasela O, Malmberg H (1997) Nasal provocation test in the diagnosis of hairdressers’ occupational rhinitis. Acta Otolaryngol Suppl 529:133–136. doi:10.3109/00016489709124104
Johannesson G, Rosqvist S, Lindh CH, Welinder H, Jönsson BAG (2001) Serum albumins are the major site for in vivo formation of hapten-carrier protein adducts in plasma from humans and guinea pigs exposed to Type-1 allergy inducing hexahydrophthalic anhydride. Clin Exp Allergy 31(7):1021–1030. doi:10.1046/j.1365-2222.2001.01109.x
Jung T, Schauer U, Heusser C, Neumann C, Rieger C (1993) Detection of intracellular cytokines by flow cytometry. J Immunol Methods 159:197–207. doi:10.1016/0022-1759(93)90158-4
Källström E, Roscher I, Andreasson A, Bäck O, van Hage-Hamsten M (2002) Decreased frequency of intracellular IFN-γ producing T cells in whole blood preparations from patients with atopic dermatitis. Exp Dermatol 11:556–563. doi:10.1034/j.1600-0625.2002.110608.x
Leino T, Tammilehto L, Luukkonen R, Nordman H (1997) Self reported respiratory symptoms and diseases among hairdressers. Occup Environ Med 54(7):452–455
Leino T, Tammilehto L, Hytonen M, Sala E, Pakkulainen H, Kanerva L (1998) Occupational skin and respiratory diseases among hairdressers. Scand J Work Environ Health 24(5):398–406
Leroyer C, Malo JL, Girard D, Dufour JG, Gautrin D (1999) Chronic rhinitis in workers at risk of reactive airways dysfunction syndrome due to exposure to chlorine. Occup Environ Med 56:334–338
Macchioni P, Kotopulos C, Talini D, De Santis M, Masino E, Paggiaro PL (1999) Asthma in hairdressers: a report of 5 cases. Med Lav 90:776–785
Malm L, Wihl JÅ, Lamm CJ, Lindqvist N (1981) Reduction of metacholine-induced nasal secretion by treatment with a new topical steroid in perennial non-allergic rhinitis. Allergy 36:209–214. doi:10.1111/j.1398-9995.1981.tb01836.x
Melillo G, Bonini S, Cocco G, Davies RJ, de Monchy JG, Frolund L et al (1997) EAACI provocation tests with allergens. Report prepared by the European Academy of Allergology and Clinical Immunology Subcommittee on provocation tests with allergens. Allergy 52(Suppl 35):1–35. doi:10.1111/j.1398-9995.1997.tb02538.x
Moscato G, Pignatti P, Yacoub MR, Romano C, Spezia S, Perfetti L (2005) Occupational asthma and occupational rhinitis in hairdressers. Chest 128:3590–3598. doi:10.1378/chest.128.5.3590
Mũnoz X, Cruz MJ, Orriols R, Bravo C, Espuga M, Morell F (2003) Occupational asthma due to persulfate salts. Chest 123:2124–2129. doi:10.1378/chest.123.6.2124
Mũnoz X, Cruz MJ, Orriols R, Torres F, Espuga M, Morell F (2004) Validation of specific inhalation challenge for diagnosis of occupational asthma due to persulphate salts. Occup Environ Med 61:861–866. doi:10.1136/oem.2004.013177
Pang S, Fiume MZ (2001) Final report of the safety assessment of ammonium, potassium and sodium persulfate. Int J Toxicol 20(Suppl 3):7–21. doi:10.1080/10915810152630710
Parra FM, Igea JM, Quirce S, Ferrando MC, Martin JA, Losada E (1992) Occupational asthma in a hairdresser caused by persulphate salts. Allergy 47:656–660. doi:10.1111/j.1398-9995.1992.tb02391.x
Picker LJ, Singh MK, Zdraveski Z, Treer JR, Waldrop SL, Bergstresser PR et al (1995) Direct demonstration of cytokine synthesis heterogeneity among human memory/effector T cells by flow cytometry. Blood 86:1408–1419
Rom WN (1992) Environmental and occupational medicine, 2nd edn. Little, Brown and Company, Boston
Syk I, Andreasson A, Truedsson L, Brunkwall J, Risberg B (1999) Postoperative downregulation of MHC class II antigen on monocytes does not differ between open and endovascular repair of aortic aneurysms. Eur J Surg 165:1035–1042. doi:10.1080/110241599750007856
van Loveren H, Steerenberg AP, Garssen J, van Bree L (1996) Interaction of environmental chemicals with respiratory sensitization. Toxicol Lett 86:163–167. doi:10.1016/0378-4274(96)03686-7
Acknowledgments
We thank I. Bensryd RN, P. Aprea BT and E. Assarsson RN for assistance with the challenges; B. Björk BT, G. Johannesson Med. Lic., K. Paulsson BT, A. Andreasson BT and S. Jönsson BT for laboratory analysis and Anna Axmon, associate professor, for statistical assistance. Financial support was obtained from the Swedish Council for Working Life and Social Research (No. 2001-0217).
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Diab, K.K., Truedsson, L., Albin, M. et al. Persulphate challenge in female hairdressers with nasal hyperreactivity suggests immune cell, but no IgE reaction. Int Arch Occup Environ Health 82, 771–777 (2009). https://doi.org/10.1007/s00420-008-0392-3
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DOI: https://doi.org/10.1007/s00420-008-0392-3