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Accuracy of 8 intraocular lens power calculation formulas in pediatric cataract patients

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Abstract

Purpose

To compare the accuracy of the eight formulas for intraocular lens (IOL) power calculation in pediatric cataract patients.

Methods

A retrospective study. A total of 68 eyes (68 patients) that underwent uneventful cataract surgery and posterior chamber IOL implantation in the capsular bag were enrolled. We compared the calculation accuracy of the 8 formulas at 1 month postoperatively and performed subgroup analysis according to age or axial length (AL).

Results

The mean age at surgery was 34.07 ± 24.60 months and mean AL was 21.12 ± 1.42 mm. The mean prediction errors (PE) of eight formulas for all patients were as follows: SRK II (− 0.66), SRK/T (− 0.44), Holladay 1 (− 0.36), Hoffer Q (− 0.09), Olsen (0.71), Barrett (0.37), Holladay 2 (− 0.70), and Haigis (0.50). There was significant difference among the 8 formulas (p < 0.0001), while no significant difference of absolute PE was found among the 8 formulas in all patients (p = 0.053). Moreover, in patients younger than 2 years old or with AL ≤ 21 mm, SRK/T formula was relatively accurate in 34% and 39% of eyes, respectively. While in patients older than 2 or with AL > 21 mm, Barrett and Haigis formulas were better (58% and 47% for Barrett, 52% and 53% for Haigis).

Conclusion

Overall, in patients younger than 2 years old or with AL ≤ 21 mm, SRK/T formulas were relatively accurate, while Barrett and Haigis formulas were better in patients older than 2 or with AL > 21 mm.

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Acknowledgments

The authors thank Linqi Xu for his helpful revisions to the manuscript.

Funding

This study was funded by research grants from the National Natural Science Foundation of China (Grant No. 81870680), Zhejiang Provincial Natural Science Foundation of China (Grant No. LY18H120008), Zhejiang Provincial Key Research and Development Program (2018C03012), and the Innovation Discipline of Zhejiang Province (lens disease in children). The funding organization had no role in the design or conduct of this research.

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Authors and Affiliations

  1. School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou Xueyuan Road, Wenzhou, 325102, Zhejiang, China

    Pingjun Chang, Lei Lin, Zhangliang Li, Jinhai Huang & Yun-e Zhao

  2. Key Laboratory of Vision Science, Ministry of Health, Wenzhou, Zhejiang, China

    Pingjun Chang, Lei Lin, Zhangliang Li, Jinhai Huang & Yun-e Zhao

  3. Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA

    Li Wang

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  1. Pingjun Chang
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  2. Lei Lin
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  4. Li Wang
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Correspondence to Yun-e Zhao.

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The authors declare that they have no conflict of interest.

Ethical approval

This study obtained the ethical approval from the Institutional Review Board of the Eye Hospital of Wenzhou Medical University. All the procedures performed were consistent with the tenets of the Declaration of Helsinki.

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Informed consent was obtained from all individual participants included in the study.

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Chang, P., Lin, L., Li, Z. et al. Accuracy of 8 intraocular lens power calculation formulas in pediatric cataract patients. Graefes Arch Clin Exp Ophthalmol 258, 1123–1131 (2020). https://doi.org/10.1007/s00417-020-04617-8

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  • DOI: https://doi.org/10.1007/s00417-020-04617-8

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