Skip to main content

Advertisement

SpringerLink
Log in

Outcomes of cataract surgery with/without vitrectomy in patients with pars planitis and immunosuppressive therapy

  • Inflammatory Disorders
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Background

The purpose of this study was to evaluate the characteristics and outcomes of cataract surgery with/without vitrectomy in patients with pars planitis who received immunosuppressive therapy.

Methods

This was a retrospective case series, single-center study. Twenty-two patients with pars planitis who received immunosuppressive therapy were included, with a median age at presentation of 9.5 years, having had cataract surgery. The following data was collected: age at presentation and at cataract surgery, time of follow-up, best-corrected visual acuity (BCVA) before the surgery and at 1 week, 1 and 6 months after the procedure, immunosuppressive therapy, complications and causes for failed visual improvement. The variables associated with an improvement in visual acuity were evaluated.

Results

All patients had phacoemulsification with intraocular lens implantation. The most common immunosuppressive therapy used for the patients was methotrexate in nine patients (40.9%). The BCVA improved from a median of 20/400 to 20/100 after 6 months of follow-up (p = 0.0005); 14 patients (63.6%) improved two lines of vision or more. No significant risk factors were found for the association with improvement in visual acuity after the surgery. No improvement in visual acuity was attributed to posterior segment manifestations or amblyopia; the most common complication was posterior capsule opacification in 11 eyes (50%). The median follow-up after the surgery was 32 months.

Conclusion

Phacoemulsification was the procedure for all the patients. Visual acuity improved in patients with pars planitis treated with immunosuppressive drugs who underwent cataract surgery, except for the patients with posterior segment complications or amblyopia.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Jabs DA, Nussenblatt RB, Rosenbaum JT (2005) Standardization of uveitis nomenclature for reporting clinical data. Results of the first international workshop. Am J Ophthalmol 140(3):509–516

    Article  PubMed  Google Scholar 

  2. Donaldson MJ, Pulido JS, Herman DC et al (2007) Pars planitis: a 20-year study of incidence, clinical features, and outcomes. Am J Ophthalmol 144:812–817

    Article  PubMed  Google Scholar 

  3. Agrawal R, Murthy S, Ganesh SK et al (2012) Cataract surgery in uveitis. Int J Inflam 2012:548453. doi:10.1155/2012/548453

  4. Bodaghi B, Terrada C, LeHoang P (2008) Cataract surgery in childhood uveitis. Int Ophthalmol Clin 48(3):173–187

    Article  PubMed  Google Scholar 

  5. Serna-Ojeda JC, Pedroza-Seres M (2014) Treatment with immunosuppressive therapy in patients with pars planitis: experience of a reference centre in Mexico. Br J Ophthalmol 98(11):1503–1507

    Article  PubMed  Google Scholar 

  6. Jabs DA, Rosenbaum JT, Foster CS et al (2000) Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol 130(4):492–513

    Article  CAS  PubMed  Google Scholar 

  7. Kaufman AH, Foster CS (1993) Cataract extraction in patients with pars planitis. Ophthalmology 100(8):1210–1217

    Article  CAS  PubMed  Google Scholar 

  8. Rosenberg KD, Feuer WJ, Davis JL (2004) Ocular complications of pediatric uveitis. Ophthalmology 111(12):2299–2306

    Article  PubMed  Google Scholar 

  9. Quiñones K, Cervantes-Castañeda RA, Hynes AY (2009) Outcomes of cataract surgery in children with chronic uveitis. J Cataract Refract Surg 35:725–731

    Article  PubMed  Google Scholar 

  10. Walker J, Rao NA, Ober RR et al (1993) A combined anterior and posterior approach to cataract surgery in patients with chronic uveitis. Int Ophthalmol 17(2):63–69

    Article  CAS  PubMed  Google Scholar 

  11. Ganesh SK, Babu K, Biswas J (2004) Phacoemulsification with intraocular lens implantation in cases of pars planitis. J Cataract Refract Surg 30(10):2072–2076

    Article  PubMed  Google Scholar 

  12. Foster CS, Fong LP, Singh G (1989) Cataract surgery and intraocular lens implantation in patients with uveitis. Ophthalmology 96(3):281–288

    Article  CAS  PubMed  Google Scholar 

  13. Hooper PL, Rao NA, Smith RE (1990) Cataract extraction in uveitis patients. Surv Ophthalmol 35(2):120–144

    Article  CAS  PubMed  Google Scholar 

  14. Suresh PS, Jones NP (2001) Phacoemulsification with intraocular lens implantation in patients with uveitis. Eye 15:621–628

    Article  CAS  PubMed  Google Scholar 

  15. Tessler HH, Farber MD (1993) Intraocular lens implantation versus no intraocular lens implantation in patients with chronic iridocyclitis and pars planitis. A randomized prospective study. Ophthalmology 100(8):1206–1209

    Article  CAS  PubMed  Google Scholar 

  16. Michelson JB, Friedlaender MH, Nozik RA (1990) Lens implant surgery in pars planitis. Ophthalmology 97(8):1023–1026

    Article  CAS  PubMed  Google Scholar 

  17. Nemet AY, Raz J, Sachs D et al (2007) Primary intraocular lens implantation in pediatric uveitis: a comparison of 2 populations. Arch Ophthalmol 125(3):354–360

    Article  PubMed  Google Scholar 

  18. Terrada C, Julian K, Cassoux N et al (2011) Cataract surgery with primary intraocular lens implantation in children with uveitis: long-term outcomes. J Cataract Refract Surg 37(11):1977–1983

    Article  PubMed  Google Scholar 

  19. Suelves AM, Siddique SS, Schurko B et al (2014) Anterior chamber intraocular lens implantation in patients with a history of chronic uveitis: five-year follow-up. J Cataract Refract Surg 40(1):77–81

    Article  PubMed  Google Scholar 

  20. Estefanous MFG, Lowder C, Meisler DM (2001) Phacoemulsification cataract extraction and posterior chamber lens implantation in patient with uveitis. Am J Ophthalmol 131(5):620–625

    Article  Google Scholar 

  21. Leung TG, Lindsley K, Kuo IC (2014) Types of intraocular lenses for cataract surgery in eyes with uveitis. Cochrane Database Syst Rev (3):CD007284

  22. Rauz S, Stavrou P, Murray PI (2000) Evaluation of foldable intraocular lenses in patients with uveitis. Ophthalmology 107(5):909–919

    Article  CAS  PubMed  Google Scholar 

  23. Baheti U, Siddique SS, Foster CS (2012) Cataract surgery in patients with history of uveitis. Saudi J Ophthalmol 26(1):55–60

    Article  PubMed  Google Scholar 

  24. Mehta S, Linton MM, Kempen JH (2014) Outcomes of cataract surgery in patients with uveitis: a systematic review and meta-analysis. Am J Ophthalmol 158(4):676–692

    Article  PubMed  Google Scholar 

  25. Fogla R, Biswas J, Ganesh SK et al (1999) Evaluation of cataract surgery in intermediate uveitis. Ophthalmic Surg Lasers 30(3):191–198

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Uveitis and Ocular Immunology, Instituto de Oftalmologia “Conde de Valenciana”, Mexico City, Mexico

    Tania Albavera-Giles, Juan Carlos Serna-Ojeda, Aida Jimenez-Corona & Miguel Pedroza-Seres

  2. Instituto de Oftalmologia “Conde de Valenciana”, Chimalpopoca 14, Cuauhtémoc, 06800, Mexico City, Mexico

    Miguel Pedroza-Seres

Authors
  1. Tania Albavera-Giles
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Juan Carlos Serna-Ojeda
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Aida Jimenez-Corona
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Miguel Pedroza-Seres
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

Design of the study: TAG, JCSO and MPS. Conduct of the study: TAG. Collection and management of the data: TAG, JCSO and AJC. Analysis and interpretation of the data: TAG, JCSO, AJC and MPS. Preparation of the manuscript: TAG, JCSO, AJC and MPS. Review and approval of the manuscript: TAG, JCSO, AJC and MPS.

Corresponding author

Correspondence to Miguel Pedroza-Seres.

Ethics declarations

Funding

No funding was received for this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Albavera-Giles, T., Serna-Ojeda, J.C., Jimenez-Corona, A. et al. Outcomes of cataract surgery with/without vitrectomy in patients with pars planitis and immunosuppressive therapy. Graefes Arch Clin Exp Ophthalmol 255, 1213–1219 (2017). https://doi.org/10.1007/s00417-017-3658-1

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-017-3658-1

Keywords

Search

Navigation